Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   JF649_RS08500 Genome accession   NZ_CP066541
Coordinates   1728728..1729324 (-) Length   198 a.a.
NCBI ID   WP_011285268.1    Uniprot ID   Q48QW4
Organism   Streptococcus pyogenes strain MGAS270     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1723728..1734324
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JF649_RS08465 (JF649_08450) - 1723789..1724094 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  JF649_RS08470 (JF649_08455) ruvX 1724106..1724525 (-) 420 WP_002982196.1 Holliday junction resolvase RuvX -
  JF649_RS08475 (JF649_08460) - 1724522..1724791 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  JF649_RS08480 (JF649_08465) spx 1724904..1725302 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  JF649_RS08485 (JF649_08470) recA 1725593..1726729 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  JF649_RS08490 (JF649_08475) cinA 1726818..1728089 (-) 1272 WP_129322339.1 competence/damage-inducible protein A Machinery gene
  JF649_RS08495 (JF649_08480) - 1728158..1728718 (-) 561 WP_136069689.1 DNA-3-methyladenine glycosylase I -
  JF649_RS08500 (JF649_08485) ruvA 1728728..1729324 (-) 597 WP_011285268.1 Holliday junction branch migration protein RuvA Machinery gene
  JF649_RS08505 (JF649_08490) - 1729326..1730546 (-) 1221 WP_002991361.1 MFS transporter -
  JF649_RS08510 (JF649_08495) hexB 1730557..1732539 (-) 1983 WP_129322343.1 DNA mismatch repair endonuclease MutL Machinery gene

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21811.12 Da        Isoelectric Point: 6.2537

>NTDB_id=455214 JF649_RS08500 WP_011285268.1 1728728..1729324(-) (ruvA) [Streptococcus pyogenes strain MGAS270]
MYDYIKGQLTKITAKYIVVETNGLGYIINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKAAELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=455214 JF649_RS08500 WP_011285268.1 1728728..1729324(-) (ruvA) [Streptococcus pyogenes strain MGAS270]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAACAAATGGACTAGGCTATAT
TATCAATGTAGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAACTGGTAACTATTTACCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGACGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGCTGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAGCGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAAACGGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q48QW4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae R6

67.005

99.495

0.667
  ruvA Streptococcus pneumoniae D39

67.005

99.495

0.667
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424