Detailed information NTG0453824

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6I02_RS10080
• Genome accession: NZ_CP066093
• Coordinates: 2174425..2176983 (-)
• Length: 852 a.a.
• NCBI ID: WP_198463553.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain FDAARGOS_1045
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2169425..2181983

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6I02_RS10050 (I6I02_10050)	ruvA	2169924..2170514 (-)	591	WP_013989915.1	Holliday junction branch migration protein RuvA	Machinery gene
I6I02_RS10055 (I6I02_10055)	-	2170672..2170893 (-)	222	WP_013989914.1	hypothetical protein	-
I6I02_RS10060 (I6I02_10060)	hexB	2171024..2172967 (-)	1944	WP_198463551.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6I02_RS10065 (I6I02_10065)	-	2173018..2173323 (-)	306	WP_037603797.1	hypothetical protein	-
I6I02_RS10070 (I6I02_10070)	brsR	2173502..2173939 (+)	438	WP_198463552.1	LytTR family DNA-binding domain-containing protein	Regulator
I6I02_RS10075 (I6I02_10075)	-	2173936..2174391 (+)	456	WP_002889588.1	DUF3021 domain-containing protein	-
I6I02_RS10080 (I6I02_10080)	hexA	2174425..2176983 (-)	2559	WP_198463553.1	DNA mismatch repair protein MutS	Machinery gene
I6I02_RS10085 (I6I02_10085)	-	2176976..2177335 (-)	360	WP_198463554.1	YlbF family regulator	-
I6I02_RS10090 (I6I02_10090)	argR	2177335..2177763 (-)	429	WP_171963598.1	arginine repressor	-
I6I02_RS10095 (I6I02_10095)	argS	2177918..2179609 (+)	1692	WP_198463555.1	arginine--tRNA ligase	-
I6I02_RS10100 (I6I02_10100)	purB	2180486..2181784 (-)	1299	WP_002886310.1	adenylosuccinate lyase	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 95547.76 Da
• Isoelectric Point: 4.6556

>NTDB_id=453824 I6I02_RS10080 WP_198463553.1 2174425..2176983(-) (hexA) [Streptococcus salivarius strain FDAARGOS_1045]
MAKEKISPGMQQYLDIKENYPDAFLLFRMGDFYELFYDDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQAYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTVVDSSKPDNANNFLVAIDKVGSRFGLAYMDVSTGEFFATELDDFSS
VCSEIQNLKAREVVVGYDLPEADEQVLVKQLNLLLSKETEVYDDVHLIDISLTDLESSVAGKLLQYVHRTQMRELSHLQK
VQHYEIKDYLQMSYATKSSLDLLENARTGKKHGSLFWLLDETKTAMGMRLLRTWIDRPLVNQATITERQNIIQVFLDNFF
ERSDLTESLKGVYDIERLASRVSFGKANPKDLIQLGHTLAQVPVIKAILDSFNDDALSRLLQELDALPELESLIRSAIDP
DAPATITEGGIIRAGFDETLDKYRKVMSEGTSWIADIEAKEREASGITTLKIDYNRKDGYYFHVTNSNLSLVPDHFFRKA
TLKNSERFGTAELAKIEGEMLEAREKSSTLEYDIFMRVREQVERYIDRLQSLAKAIATVDVLQSLAVVAETNHYVRPIFN
DEHRIVIDQGRHAVVEKVMGVQEYIPNTITFDSQTNIQLITGPNMSGKSTYMRQLALSVVVAQMGSYVPADSIDLPVFDA
IYTRIGAADDLISGQSTFMVEMMEANQAIKRATPNSLIIFDELGRGTATYDGMALAQSIIEFIHDKVGAKTMFATHYHEL
TALSNTLTHLVNVHVATLEKDGEVTFLHKIVDGPADKSYGIHVAKIAGLPADLLERADTILTQLEGDTVTIQPQEKVSSQ
EKPATETHVNEQISLFDDFTENPVLQELRDLDIYNMTPMQVMMAVADLKQKL

Nucleotide

• Length: 2559 bp

>NTDB_id=453824 I6I02_RS10080 WP_198463553.1 2174425..2176983(-) (hexA) [Streptococcus salivarius strain FDAARGOS_1045]
ATGGCTAAGGAAAAAATATCTCCAGGAATGCAGCAGTATTTGGATATCAAGGAAAATTATCCAGATGCTTTTTTGCTGTT
TCGGATGGGGGATTTTTACGAATTATTTTACGATGATGCCGTTAAGGCTGCTCAAATTTTGGAAATTAGCCTAACCAGTC
GTAATAAGAACGCAGATAATCCCATTCCTATGGCAGGTGTTCCTTATCATTCGGCTCAAGCCTATATTGATGTCTTGGTT
GAGATGGGCTACAAAGTAGCCATTGCTGAGCAGATGGAGGACCCTAAACAGGCTGTTGGCGTGGTTAAGCGTGAGGTAGT
TCAGGTTATCACGCCAGGGACAGTGGTTGACAGCTCTAAACCAGATAATGCCAACAATTTCTTAGTAGCCATTGACAAGG
TTGGAAGTCGATTCGGACTGGCCTATATGGATGTGTCAACGGGTGAATTTTTTGCGACAGAGTTGGATGATTTCAGTTCA
GTTTGTAGTGAAATTCAGAATCTTAAGGCACGTGAAGTAGTCGTTGGGTATGATTTACCTGAAGCTGATGAACAAGTTTT
GGTGAAGCAACTCAACCTGCTTCTCTCCAAGGAAACAGAGGTTTACGATGATGTCCACTTGATTGACATTAGTTTGACAG
ATTTGGAAAGCAGTGTGGCGGGTAAACTTCTCCAGTATGTTCATCGTACTCAGATGCGAGAGCTCAGTCATTTACAAAAG
GTTCAGCACTATGAGATTAAAGATTACTTGCAGATGTCCTATGCGACCAAGTCAAGTTTGGATTTACTGGAAAATGCTAG
AACGGGCAAGAAACACGGATCTCTTTTCTGGCTCTTGGATGAAACCAAGACAGCTATGGGAATGCGTCTCTTGCGAACTT
GGATTGATCGTCCTTTAGTGAATCAAGCCACTATCACCGAGCGTCAGAATATTATCCAAGTTTTCTTGGACAATTTCTTT
GAGCGTAGTGACTTGACTGAGAGTCTAAAAGGTGTTTACGATATTGAGCGCCTGGCCAGTCGTGTTTCCTTTGGCAAGGC
TAATCCAAAAGATTTGATTCAACTAGGTCATACTTTGGCTCAAGTACCGGTGATTAAGGCGATTTTGGATTCTTTTAATG
ACGATGCCTTGTCACGTCTTTTACAAGAGTTAGATGCTCTGCCAGAATTAGAGAGTTTGATTCGGTCGGCTATTGATCCA
GATGCTCCTGCAACCATTACAGAAGGTGGCATTATCCGTGCTGGTTTTGATGAGACCTTGGACAAGTATCGCAAGGTGAT
GAGTGAGGGAACGTCATGGATCGCAGATATCGAAGCTAAAGAACGTGAAGCGTCTGGTATTACAACACTAAAAATTGATT
ATAACCGTAAAGATGGTTATTACTTCCATGTGACTAACTCTAACCTTAGCTTGGTTCCTGACCATTTCTTCCGCAAGGCA
ACCCTGAAAAATTCAGAGCGCTTTGGAACTGCTGAGTTGGCTAAGATAGAAGGTGAAATGCTCGAGGCACGTGAAAAGTC
ATCAACGCTAGAGTATGATATTTTCATGCGTGTCCGTGAGCAGGTTGAACGCTATATTGACCGTTTGCAATCTTTGGCTA
AAGCTATTGCGACAGTCGATGTGCTTCAGAGTCTAGCTGTTGTAGCAGAGACCAATCATTATGTTCGCCCTATTTTCAAT
GATGAGCATCGTATTGTTATTGATCAAGGCCGTCATGCAGTGGTTGAGAAGGTTATGGGAGTTCAAGAATACATCCCAAA
CACCATTACCTTTGACAGTCAGACCAATATTCAGCTCATCACAGGACCAAATATGAGTGGTAAATCCACCTATATGCGTC
AGTTAGCCTTGTCAGTAGTTGTGGCTCAGATGGGGTCTTATGTGCCAGCAGATAGTATTGACTTGCCAGTTTTTGACGCC
ATCTATACACGTATTGGTGCTGCAGATGACTTGATTTCAGGGCAGTCGACCTTCATGGTTGAGATGATGGAGGCTAACCA
GGCTATTAAGCGGGCGACACCTAATTCCTTGATTATTTTTGATGAGTTGGGACGTGGGACAGCTACCTATGACGGTATGG
CTCTGGCCCAGTCTATCATTGAGTTTATTCATGACAAGGTGGGGGCTAAAACCATGTTTGCTACCCATTATCATGAGTTG
ACAGCTCTGTCAAATACTTTGACACACCTTGTCAACGTTCATGTGGCGACACTTGAAAAGGATGGTGAGGTGACTTTCCT
TCACAAGATTGTCGATGGCCCAGCCGATAAATCTTATGGTATTCATGTGGCTAAGATTGCAGGTTTACCAGCAGATTTAC
TGGAACGTGCTGACACCATCTTGACACAACTAGAGGGCGATACAGTTACCATCCAACCTCAGGAAAAGGTATCGTCTCAA
GAGAAACCTGCCACTGAAACGCATGTCAACGAGCAAATCTCTCTCTTTGATGATTTTACTGAAAATCCAGTTCTTCAAGA
GTTGCGTGATTTAGATATTTACAACATGACACCTATGCAAGTCATGATGGCTGTAGCAGATTTAAAACAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.061	100	0.741
mutS	Pseudomonas stutzeri strain ATCC 17587	35.954	100	0.365