Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6I02_RS10060 Genome accession   NZ_CP066093
Coordinates   2171024..2172967 (-) Length   647 a.a.
NCBI ID   WP_198463551.1    Uniprot ID   -
Organism   Streptococcus salivarius strain FDAARGOS_1045     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2166024..2177967
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I02_RS10030 (I6I02_10030) spx 2166252..2166650 (-) 399 WP_002886328.1 transcriptional regulator Spx -
  I6I02_RS10035 (I6I02_10035) recA 2166819..2167958 (-) 1140 WP_002889600.1 recombinase RecA Machinery gene
  I6I02_RS10040 (I6I02_10040) cinA 2167999..2169264 (-) 1266 WP_060972115.1 competence/damage-inducible protein A Machinery gene
  I6I02_RS10045 (I6I02_10045) - 2169361..2169915 (-) 555 WP_013989916.1 DNA-3-methyladenine glycosylase I -
  I6I02_RS10050 (I6I02_10050) ruvA 2169924..2170514 (-) 591 WP_013989915.1 Holliday junction branch migration protein RuvA Machinery gene
  I6I02_RS10055 (I6I02_10055) - 2170672..2170893 (-) 222 WP_013989914.1 hypothetical protein -
  I6I02_RS10060 (I6I02_10060) hexB 2171024..2172967 (-) 1944 WP_198463551.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6I02_RS10065 (I6I02_10065) - 2173018..2173323 (-) 306 WP_037603797.1 hypothetical protein -
  I6I02_RS10070 (I6I02_10070) brsR 2173502..2173939 (+) 438 WP_198463552.1 LytTR family DNA-binding domain-containing protein Regulator
  I6I02_RS10075 (I6I02_10075) - 2173936..2174391 (+) 456 WP_002889588.1 DUF3021 domain-containing protein -
  I6I02_RS10080 (I6I02_10080) hexA 2174425..2176983 (-) 2559 WP_198463553.1 DNA mismatch repair protein MutS Machinery gene
  I6I02_RS10085 (I6I02_10085) - 2176976..2177335 (-) 360 WP_198463554.1 YlbF family regulator -
  I6I02_RS10090 (I6I02_10090) argR 2177335..2177763 (-) 429 WP_171963598.1 arginine repressor -

Sequence

Protein


Download         Length: 647 a.a.        Molecular weight: 72660.79 Da        Isoelectric Point: 5.2029

>NTDB_id=453822 I6I02_RS10060 WP_198463551.1 2171024..2172967(-) (hexB) [Streptococcus salivarius strain FDAARGOS_1045]
MPKIIELPEVLANQIAAGEVVERPASVVKELVENAIDAGSTQITIEVEESGLSKIQITDNGEGMAQSDVAMSLRRHATSK
IKNQGDLFRIRTLGFRGEALPSIASISHLTIVTAADGEAYGTKLVAKGGEIESQDPISTPVGTKITVENLFYNTPARLKY
MKSLQAELAHIVDVVNRLSLAHPEVAFTLLNDGRQLTQTSGTGDLRQAIAGIYGLTTAKKMVEISNSDLDFEVSGYVSLP
ELTRANRNYITILINGRYIKNFLLNRAIFDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMALISS
AIAQSLREQDLIPDALENLAKSSTRCATKPVQTSLPLKQTNLYYDSSRNDFFVKPETVQEDIKPLVSELESPVSSVENKP
QPSVKQAQRSVDESDDKHEKLDYKNKSKMKRMLETLDNEETSTFPELEFFGQMHGTYLFAQGQGGLYIIDQHAAQERVKY
EYYRENIGEVDSSLQQLLVPYLFEFSGSDYISLQEKMPLLNQVGIYLEPYGNNTFILREHPIWMKEEEIESAVYEMCDML
LLTNEVSVKTYRAELAIMMSCKRSIKANHALDDYSARDLLVQLAQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTS
LRDLGKY

Nucleotide


Download         Length: 1944 bp        

>NTDB_id=453822 I6I02_RS10060 WP_198463551.1 2171024..2172967(-) (hexB) [Streptococcus salivarius strain FDAARGOS_1045]
ATGCCAAAAATCATCGAATTGCCTGAAGTTCTAGCCAATCAGATTGCTGCTGGAGAGGTCGTAGAGCGACCAGCTAGTGT
AGTTAAAGAGCTGGTGGAAAATGCTATTGATGCAGGCAGCACCCAGATTACCATTGAAGTTGAAGAATCAGGCCTCTCAA
AAATTCAAATTACAGACAATGGCGAAGGAATGGCTCAATCTGATGTAGCTATGAGTTTGCGCCGTCATGCAACAAGTAAA
ATCAAAAATCAAGGAGATCTCTTTCGTATTCGAACCCTTGGTTTTCGAGGTGAGGCCCTACCATCAATAGCTTCTATCAG
CCACCTAACTATTGTGACAGCAGCGGATGGAGAAGCCTATGGGACTAAACTGGTTGCCAAGGGTGGGGAAATTGAGAGTC
AGGATCCTATTTCAACACCAGTTGGAACAAAGATTACCGTTGAAAACTTATTTTATAACACCCCAGCTCGTCTCAAGTAT
ATGAAGAGTTTACAGGCCGAGTTGGCTCATATTGTCGATGTTGTCAATCGTCTGAGTCTAGCTCATCCCGAAGTTGCCTT
CACCTTGCTTAATGACGGTCGTCAGTTGACACAGACCTCAGGTACTGGAGACCTCCGTCAAGCTATTGCCGGGATTTATG
GTTTAACAACGGCTAAAAAAATGGTGGAAATTTCAAATTCTGACCTTGATTTTGAAGTTTCTGGCTATGTCAGCCTTCCT
GAATTAACTCGTGCAAATCGTAACTACATCACGATTCTCATTAACGGACGCTATATAAAAAACTTCCTGCTTAACCGTGC
TATTTTTGATGGTTATGGTTCTAAACTCATGGTAGGACGCTTCCCTATTGCAGTTATTGATATTCAAATTGATCCCTACC
TGGCCGATGTCAATGTTCACCCAACCAAGCAGGAAGTACGTATCTCTAAAGAAAAAGAGCTCATGGCCCTTATCAGCTCT
GCCATTGCTCAAAGCCTTAGAGAGCAGGATTTGATTCCTGATGCCCTTGAAAATCTAGCCAAGTCTAGTACCAGATGTGC
AACTAAGCCAGTTCAAACCAGTCTCCCACTCAAACAAACCAATCTTTACTATGATAGTAGTCGTAATGATTTCTTTGTCA
AACCAGAGACAGTCCAAGAAGATATCAAACCTCTTGTATCGGAGTTAGAGTCCCCAGTTTCATCGGTAGAAAACAAACCG
CAACCTTCTGTTAAACAGGCACAACGTTCAGTAGATGAAAGTGATGACAAACACGAAAAACTCGACTATAAAAACAAGTC
GAAAATGAAGCGCATGCTCGAAACTCTAGATAATGAGGAAACATCAACCTTCCCTGAATTGGAGTTTTTTGGTCAAATGC
ATGGAACCTATCTCTTTGCGCAAGGACAAGGCGGACTTTACATCATTGACCAGCATGCTGCCCAAGAACGTGTCAAGTAT
GAGTACTATCGCGAAAATATTGGTGAGGTTGACAGTAGTTTACAACAGCTTTTGGTTCCCTATCTCTTTGAATTTTCAGG
TTCGGATTACATTAGTTTACAAGAAAAAATGCCTCTTCTTAATCAGGTTGGTATCTATTTAGAGCCTTATGGGAATAACA
CCTTCATTCTTCGTGAACATCCTATCTGGATGAAGGAAGAAGAGATTGAATCTGCAGTCTATGAGATGTGCGACATGCTT
CTTTTGACGAATGAAGTGTCTGTCAAGACCTACCGTGCTGAGTTAGCCATCATGATGAGTTGTAAACGTTCAATCAAGGC
CAATCATGCTCTCGATGATTACTCTGCGCGTGACCTTCTAGTACAGCTTGCACAGTGTAAAAACCCCTACAATTGCCCTC
ACGGACGTCCTGTACTTGTCAATTTTACAAAGTCTGATATGGAAAAAATGTTCCGTCGAATTCAAGAAAATCATACTAGT
CTACGTGACTTAGGGAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(448-591)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.637

100

0.713