Detailed information NTG0453636

Bioinformatically predicted

Overview

• Name: vicK
• Type: Regulator
• Locus tag: I6H73_RS02435
• Genome accession: NZ_CP066073
• Coordinates: 470174..471526 (+)
• Length: 450 a.a.
• NCBI ID: WP_003057196.1
• Uniprot ID: A0ABU0A534
• Organism: Streptococcus dysgalactiae strain FDAARGOS_1016
• Function: repress comCDE expression; repress comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 465174..476526

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H73_RS02410 (I6H73_02410)	-	466241..466888 (-)	648	WP_003057245.1	amino acid ABC transporter permease	-
I6H73_RS02415 (I6H73_02415)	-	466903..467604 (-)	702	WP_003057191.1	amino acid ABC transporter permease	-
I6H73_RS02420 (I6H73_02420)	-	467618..468418 (-)	801	WP_003057243.1	transporter substrate-binding domain-containing protein	-
I6H73_RS02425 (I6H73_02425)	-	468418..469212 (-)	795	WP_003057217.1	amino acid ABC transporter ATP-binding protein	-
I6H73_RS02430 (I6H73_02430)	yycF	469471..470181 (+)	711	WP_003057225.1	response regulator YycF	-
I6H73_RS02435 (I6H73_02435)	vicK	470174..471526 (+)	1353	WP_003057196.1	cell wall metabolism sensor histidine kinase VicK	Regulator
I6H73_RS02440 (I6H73_02440)	vicX	471530..472339 (+)	810	WP_003057211.1	MBL fold metallo-hydrolase	Regulator
I6H73_RS02445 (I6H73_02445)	rnc	473097..473789 (+)	693	WP_003057240.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51490.13 Da
• Isoelectric Point: 5.9423

>NTDB_id=453636 I6H73_RS02435 WP_003057196.1 470174..471526(+) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1016]
MTRDIIGNLSAFELAILLLLVFVAFYFIHLAVRDYRNARIIRMMSHKIRDLINGRYTDMINEKADIELMELADQLNDLSD
VFRLTHENLAQEKKRLASILAYMSDGVLATDRSGKIIMINETARKQLNLTKEKALEKNITDLLEGDTPYTYRELVSKTPV
VTVNSRNDMGEFVTLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGAIK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNQVTQLSVEMTNFTAFMTSILNRFDLVKNQHTGTGKVYEIVRDYPITS
VWLEIDNDKMTQVIENILNNAIKYSPDGGKITVRMKTTDTQLIISISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHHGFIWAKSDYGKGSTFTIVLPYEKDAAIYEEWEDDID

Nucleotide

• Length: 1353 bp

>NTDB_id=453636 I6H73_RS02435 WP_003057196.1 470174..471526(+) (vicK) [Streptococcus dysgalactiae strain FDAARGOS_1016]
ATGACTAGAGATATCATTGGAAACTTATCCGCTTTTGAATTAGCGATTCTCTTATTACTTGTTTTTGTTGCCTTTTATTT
TATTCACTTAGCGGTGCGTGATTACCGAAATGCCCGTATTATTCGAATGATGAGCCATAAAATCAGAGACCTGATTAATG
GCCGTTATACCGACATGATTAACGAAAAGGCTGACATTGAATTGATGGAACTGGCAGATCAGTTAAACGATCTCTCAGAC
GTGTTTCGCTTAACCCATGAGAATCTTGCCCAGGAAAAAAAACGCTTGGCCAGCATTCTGGCCTATATGTCAGATGGCGT
ACTTGCCACAGACCGGTCTGGTAAAATCATCATGATTAACGAGACAGCTCGCAAGCAGCTCAATCTGACCAAGGAGAAGG
CCCTTGAAAAGAACATTACCGATTTGTTGGAGGGAGATACCCCCTATACCTATCGTGAATTGGTTTCCAAAACGCCTGTT
GTGACGGTCAATAGTCGCAATGACATGGGTGAGTTTGTTACATTACGTTTACGCTTCGCCTTAAACAGACGAGAAAGTGG
TTTTATTTCTGGTTTGGTTGTGGTGCTCCATGACACTACAGAACAGGAAAAGGAAGAACGTGAACGCCGGTTGTTTGTTT
CTAATGTGAGTCATGAGTTGAGAACACCTTTGACATCGGTGAAATCCTACTTGGAGGCTCTTGACGAAGGTGCCATCAAG
GAAGATATTGCTCCAAGTTTCATAAAAGTTTCTCTTGATGAAACCAATCGGATGATGCGTATGATTTCCGATCTTTTAAA
CTTGTCTCGCATTGATAACCAAGTAACTCAGTTATCTGTCGAGATGACCAATTTTACAGCTTTTATGACATCTATCCTGA
ACCGATTTGACCTAGTTAAAAACCAGCACACCGGTACTGGCAAGGTTTATGAAATTGTGAGAGACTATCCGATTACCTCT
GTTTGGCTGGAAATTGATAATGATAAGATGACGCAGGTTATTGAAAATATCCTAAACAACGCGATTAAATACTCTCCTGA
TGGTGGGAAAATCACTGTTCGCATGAAAACAACCGACACGCAATTGATTATTTCCATCTCAGACCAAGGCTTAGGCATTC
CGAAGAAGGATCTGCCCCTTATTTTTGACCGTTTTTACCGTGTGGACAAGGCAAGAAGCCGTGCTCAAGGTGGAACTGGT
CTAGGGCTTGCCATTGCCAAAGAAATTATTAAGCAGCATCACGGGTTTATTTGGGCGAAGAGTGATTATGGCAAAGGATC
AACCTTTACCATCGTCTTGCCATATGAAAAAGATGCTGCCATTTACGAAGAGTGGGAGGATGACATAGATTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (95-165)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vicK	Streptococcus mutans UA159	72.947	92	0.671
micB	Streptococcus pneumoniae Cp1015	66.824	94.444	0.631