Detailed information NTG0453620

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: FX987_RS05510
• Genome accession: NZ_CP054580
• Coordinates: 1234482..1235327 (-)
• Length: 281 a.a.
• NCBI ID: WP_022523593.1
• Uniprot ID: A0A1G8KUI0
• Organism: Vreelandella titanicae strain GPM3
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1229482..1240327

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FX987_RS05480 (FX987_01096)	-	1230564..1230938 (+)	375	WP_022523599.1	histone-like nucleoid-structuring protein, MvaT/MvaU family	-
FX987_RS05485 (FX987_01097)	-	1231027..1231857 (-)	831	WP_022523598.1	helix-turn-helix transcriptional regulator	-
FX987_RS05490 (FX987_01098)	-	1232232..1232591 (+)	360	WP_035537408.1	hypothetical protein	-
FX987_RS05495 (FX987_01099)	-	1232615..1233502 (-)	888	WP_022523596.1	hypothetical protein	-
FX987_RS05500 (FX987_01100)	yacG	1233542..1233775 (-)	234	WP_022523595.1	DNA gyrase inhibitor YacG	-
FX987_RS05505 (FX987_01101)	coaE	1233811..1234413 (-)	603	WP_022523594.1	dephospho-CoA kinase	-
FX987_RS05510 (FX987_01102)	pilD	1234482..1235327 (-)	846	WP_022523593.1	prepilin peptidase	Machinery gene
FX987_RS05515 (FX987_01103)	pilC	1235520..1236752 (-)	1233	WP_022523592.1	type II secretion system F family protein	Machinery gene
FX987_RS05520 (FX987_01104)	pilB	1236756..1238504 (-)	1749	WP_089690942.1	type IV-A pilus assembly ATPase PilB	Machinery gene
FX987_RS05525 (FX987_01105)	-	1238746..1239261 (+)	516	WP_022523590.1	pilin	-
FX987_RS05530 (FX987_01106)	-	1239370..1239804 (+)	435	WP_022523589.1	anti-virulence regulator CigR family protein	-

Sequence

Protein

• Length: 281 a.a.
• Molecular weight: 30767.10 Da
• Isoelectric Point: 7.2769

>NTDB_id=453620 FX987_RS05510 WP_022523593.1 1234482..1235327(-) (pilD) [Vreelandella titanicae strain GPM3]
MHHPPFILWLIVLLIGLCLGSFLNVVITRLPVMLMRGWRNEAREALELSAEHSPRFNLATPGSMCPRCEAPIAWHDNLPL
IGWIKRRGRCAECQTPISVQYPLVEVAGGLLAMAVLALHGLTAESVFVYGACLMLLVLAVIDFRTQLLPDIITLPLLWAG
LLFQLLFQPLMLPSAVIGAMVGYLSLWSFYWLFKLATGKEGMGYGDFKLLAALGAWLGWSFLPLILILSAGLGAIVGLVA
QAYSPNLRGTPLPFGPFLALAGWVALLVGDEIMAMYLNLLM

Nucleotide

• Length: 846 bp

>NTDB_id=453620 FX987_RS05510 WP_022523593.1 1234482..1235327(-) (pilD) [Vreelandella titanicae strain GPM3]
ATGCATCACCCTCCGTTTATCCTGTGGTTAATCGTTTTATTGATTGGGCTATGCCTGGGCAGTTTTCTAAATGTGGTGAT
TACGCGCCTGCCGGTGATGCTGATGCGTGGCTGGCGTAACGAAGCCCGCGAAGCACTTGAGCTTAGCGCGGAACACTCAC
CACGCTTTAATTTGGCCACACCAGGCTCTATGTGTCCACGCTGTGAAGCCCCCATTGCATGGCACGACAACCTGCCACTG
ATTGGCTGGATAAAGCGCCGCGGCCGCTGCGCTGAGTGCCAAACGCCGATTAGCGTTCAATATCCTCTGGTAGAAGTAGC
CGGTGGCTTACTGGCCATGGCGGTGCTAGCGCTCCACGGGCTTACGGCAGAATCAGTCTTCGTTTACGGGGCCTGTCTGA
TGCTGTTAGTGCTCGCCGTGATCGACTTTCGCACCCAGCTTCTCCCTGACATCATCACCCTCCCCTTGCTTTGGGCAGGG
TTACTGTTTCAGCTCCTCTTCCAGCCACTGATGCTGCCAAGTGCCGTTATCGGCGCAATGGTAGGCTATCTTTCACTGTG
GAGCTTTTATTGGCTATTCAAACTGGCCACCGGCAAAGAGGGTATGGGCTATGGCGACTTTAAGCTGCTGGCAGCACTAG
GCGCCTGGTTGGGTTGGAGTTTTTTACCGCTAATATTGATACTTTCCGCAGGGCTTGGGGCCATTGTTGGGCTAGTTGCC
CAGGCCTACTCACCTAACCTACGCGGCACACCGCTTCCCTTCGGCCCTTTTCTCGCCCTCGCCGGCTGGGTGGCGTTGTT
AGTCGGTGATGAAATAATGGCAATGTATCTCAACCTGCTTATGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (14-116)

• Type IV leader peptidase family (Peptidase_A24) (132-238)

3D structure

• AlphaFold DB: A0A1G8KUI0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio cholerae strain A1552	48.929	99.644	0.488
pilD	Acinetobacter baumannii D1279779	46.909	97.865	0.459
pilD	Acinetobacter nosocomialis M2	46.909	97.865	0.459
pilD	Vibrio campbellii strain DS40M4	42.958	100	0.434
pilD	Neisseria gonorrhoeae MS11	44.828	92.883	0.416