Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   HSZ50_RS04615 Genome accession   NZ_CP054575
Coordinates   946166..946795 (+) Length   209 a.a.
NCBI ID   WP_069794961.1    Uniprot ID   -
Organism   Staphylococcus saprophyticus strain UTI-050     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 941166..951795
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ50_RS04590 (HSZ50_04590) - 942015..943001 (-) 987 WP_174604982.1 aromatic acid exporter family protein -
  HSZ50_RS04595 (HSZ50_04595) map 943176..943928 (+) 753 WP_011302778.1 type I methionyl aminopeptidase -
  HSZ50_RS04600 (HSZ50_04600) - 944032..944418 (+) 387 WP_011302779.1 hypothetical protein -
  HSZ50_RS04605 (HSZ50_04605) liaF 944435..945136 (+) 702 WP_069794963.1 cell wall-active antibiotics response protein LiaF -
  HSZ50_RS04610 (HSZ50_04610) vraS 945133..946176 (+) 1044 WP_069794962.1 sensor histidine kinase Regulator
  HSZ50_RS04615 (HSZ50_04615) vraR 946166..946795 (+) 630 WP_069794961.1 response regulator transcription factor Regulator
  HSZ50_RS04620 (HSZ50_04620) - 946952..948124 (-) 1173 WP_069794960.1 YihY/virulence factor BrkB family protein -
  HSZ50_RS04625 (HSZ50_04625) - 948536..948820 (-) 285 WP_002482848.1 hypothetical protein -
  HSZ50_RS04630 (HSZ50_04630) - 948827..949291 (-) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  HSZ50_RS04635 (HSZ50_04635) - 949426..949629 (+) 204 WP_069794959.1 DUF1128 family protein -
  HSZ50_RS04640 (HSZ50_04640) - 949643..950881 (+) 1239 WP_069794958.1 aminopeptidase -
  HSZ50_RS04645 (HSZ50_04645) - 951095..951616 (+) 522 WP_011302785.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23670.16 Da        Isoelectric Point: 4.6997

>NTDB_id=453594 HSZ50_RS04615 WP_069794961.1 946166..946795(+) (vraR) [Staphylococcus saprophyticus strain UTI-050]
MPVKVLFVDDHEMVRIGISSYLSTQSDIDVVGEGKSGKDAIEKAHELKPDLILMDLLMDDMDGVEATEQVKKDLPNIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSASDIAEAIRKTYNNESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=453594 HSZ50_RS04615 WP_069794961.1 946166..946795(+) (vraR) [Staphylococcus saprophyticus strain UTI-050]
ATGCCGGTTAAAGTATTATTTGTTGATGATCATGAAATGGTTCGAATAGGTATTTCTAGTTATTTATCCACACAATCAGA
TATAGATGTCGTAGGGGAAGGTAAGTCAGGAAAAGATGCAATCGAAAAAGCACATGAACTGAAACCGGACCTAATTTTAA
TGGATTTACTTATGGACGATATGGATGGTGTCGAAGCAACTGAACAAGTTAAAAAAGACTTGCCAAATATTAAAGTTGTC
ATGCTTACGAGTTATATTGAAGATAACGAAGTCTATCGTGCACTTGATTCCGGTGTAGATAGCTATATATTGAAAACAAC
AAGTGCTAGTGATATTGCTGAAGCGATTCGTAAGACTTACAATAATGAGTCAGTATTTGAAGCAGAAGTCCTAGTTAAAA
TGAGAAATAGGATGAAACAACGAGCTGAATTGTATGAAATGCTCACAGAACGTGAAATGGAGATTTTATTACTGATTGCT
AAAGGTTACTCTAACCAAGAGATTGCCAGCGCTTCACATATTACGATTAAAACAGTGAAAACGCATGTAAGTAATATCCT
AAGTAAATTAGAAGTTCAAGATAGAACTCAAGCCGTCATATATGCATTCCAGCACAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, luxR family (GerE)

(147-202)

Response regulator receiver domain (Response_reg)

(5-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.474

100

0.895
  degU Bacillus subtilis subsp. subtilis str. 168

33.929

100

0.364