Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraS   Type   Regulator
Locus tag   HSZ50_RS04610 Genome accession   NZ_CP054575
Coordinates   945133..946176 (+) Length   347 a.a.
NCBI ID   WP_069794962.1    Uniprot ID   -
Organism   Staphylococcus saprophyticus strain UTI-050     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 940133..951176
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HSZ50_RS04575 (HSZ50_04575) - 940527..940742 (+) 216 WP_103301910.1 helix-turn-helix domain-containing protein -
  HSZ50_RS04580 (HSZ50_04580) - 940760..941065 (+) 306 WP_174604981.1 helix-turn-helix domain-containing protein -
  HSZ50_RS04585 (HSZ50_04585) - 941071..941937 (+) 867 WP_256107237.1 IS3 family transposase -
  HSZ50_RS04590 (HSZ50_04590) - 942015..943001 (-) 987 WP_174604982.1 aromatic acid exporter family protein -
  HSZ50_RS04595 (HSZ50_04595) map 943176..943928 (+) 753 WP_011302778.1 type I methionyl aminopeptidase -
  HSZ50_RS04600 (HSZ50_04600) - 944032..944418 (+) 387 WP_011302779.1 hypothetical protein -
  HSZ50_RS04605 (HSZ50_04605) liaF 944435..945136 (+) 702 WP_069794963.1 cell wall-active antibiotics response protein LiaF -
  HSZ50_RS04610 (HSZ50_04610) vraS 945133..946176 (+) 1044 WP_069794962.1 sensor histidine kinase Regulator
  HSZ50_RS04615 (HSZ50_04615) vraR 946166..946795 (+) 630 WP_069794961.1 response regulator transcription factor Regulator
  HSZ50_RS04620 (HSZ50_04620) - 946952..948124 (-) 1173 WP_069794960.1 YihY/virulence factor BrkB family protein -
  HSZ50_RS04625 (HSZ50_04625) - 948536..948820 (-) 285 WP_002482848.1 hypothetical protein -
  HSZ50_RS04630 (HSZ50_04630) - 948827..949291 (-) 465 WP_011302783.1 low molecular weight protein-tyrosine-phosphatase -
  HSZ50_RS04635 (HSZ50_04635) - 949426..949629 (+) 204 WP_069794959.1 DUF1128 family protein -
  HSZ50_RS04640 (HSZ50_04640) - 949643..950881 (+) 1239 WP_069794958.1 aminopeptidase -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39992.51 Da        Isoelectric Point: 6.5959

>NTDB_id=453593 HSZ50_RS04610 WP_069794962.1 945133..946176(+) (vraS) [Staphylococcus saprophyticus strain UTI-050]
MNHYFRAIGSMLILVYSTFFAIFFIDKVFVNIMYFQGMFYTQIFGIPVLLFLNLMVILLCIIVGSVLAYKINQQNHWLKD
QIERSIEGQTVGINDQNIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELKAPLDQQIPVLEKMIQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVVHDI
EEFKVPKGIEDHLFRITQEAISNTLRHSKGTKVTIELFNREEYLLLRIQDNGKGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDAGTRIEVKAPLNKEDSNAG

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=453593 HSZ50_RS04610 WP_069794962.1 945133..946176(+) (vraS) [Staphylococcus saprophyticus strain UTI-050]
ATGAATCACTACTTTAGAGCGATCGGGTCCATGTTGATATTAGTATATAGTACGTTTTTTGCCATATTCTTTATTGATAA
AGTATTTGTTAATATAATGTATTTTCAAGGTATGTTTTATACTCAAATATTTGGCATACCTGTACTGCTTTTTTTAAATC
TAATGGTGATTTTACTCTGTATTATTGTAGGTTCTGTCTTAGCATATAAAATCAATCAGCAAAATCATTGGTTAAAAGAT
CAAATTGAACGTTCAATAGAAGGTCAAACAGTGGGTATCAATGATCAAAATATTGAATTATACAACGAAACAATCGAACT
ATATCAAACGCTTGTGCCTTTAAATCAAGAAGTACATAAATTAAGAATGAAAACACAGAACCTGACGAATGAATCTTATA
ATATCAATGATGTTAAAGTTAAGAAAATTATAGAAGACGAACGCCAACGTTTAGCGCGTGAATTACATGATTCAGTTAGT
CAACAATTATTCGCAGCAAGTATGATGTTATCAGCAATTAAAGAGACAGAATTGAAGGCCCCATTGGACCAACAAATACC
AGTATTAGAAAAAATGATTCAAGATTCCCAATTAGAAATGAGAGCACTACTATTACACTTAAGACCTATTGGTTTGAAAG
ATAAATCTTTAGGTGAGGGTATTAAAGATTTAGTCGTTGATTTACAGAAAAAAGTACCAATGAAAGTGGTACATGATATT
GAAGAATTCAAAGTACCAAAAGGTATCGAGGACCATTTATTCCGTATTACGCAAGAAGCCATTTCTAATACGCTAAGACA
TTCTAAAGGAACGAAGGTCACAATTGAATTATTTAATAGGGAAGAATATTTGTTATTGCGTATACAAGATAATGGTAAAG
GGTTTAATGTAGATGATAAGGTAGAACAAAGTTATGGATTAAAAAATATGCGCGAACGTGCACTAGAAATAGGTGCAACA
TTTCATATCGTTTCTTTGCCTGATGCAGGTACGAGAATTGAAGTGAAGGCACCATTAAATAAGGAGGATTCAAATGCCGG
TTAA

Domains

Predicted by InterproScan.

Histidine kinase (HisKA_3)

(147-210)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(249-340)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraS Staphylococcus aureus N315

87.791

99.135

0.87