Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   FOC72_RS01590 Genome accession   NZ_CP054570
Coordinates   326162..327460 (+) Length   432 a.a.
NCBI ID   WP_002893483.1    Uniprot ID   A0A859ELX9
Organism   Streptococcus sanguinis strain FDAARGOS_770     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 321162..332460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC72_RS01565 (FOC72_01565) - 321908..322540 (+) 633 WP_002893493.1 response regulator transcription factor -
  FOC72_RS01570 (FOC72_01570) - 322580..323980 (+) 1401 WP_002893492.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  FOC72_RS01575 (FOC72_01575) - 323980..324339 (+) 360 WP_002893490.1 S1 RNA-binding domain-containing protein -
  FOC72_RS01580 (FOC72_01580) cysK 324444..325373 (-) 930 WP_002893488.1 cysteine synthase A -
  FOC72_RS01585 (FOC72_01585) - 325474..326106 (-) 633 WP_002893485.1 YigZ family protein -
  FOC72_RS01590 (FOC72_01590) comFA/cflA 326162..327460 (+) 1299 WP_002893483.1 DEAD/DEAH box helicase Machinery gene
  FOC72_RS01595 (FOC72_01595) comFC/cflB 327457..328122 (+) 666 WP_002893482.1 ComF family protein Machinery gene
  FOC72_RS01600 (FOC72_01600) raiA 328204..328746 (+) 543 WP_002893481.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49555.29 Da        Isoelectric Point: 8.2891

>NTDB_id=453484 FOC72_RS01590 WP_002893483.1 326162..327460(+) (comFA/cflA) [Streptococcus sanguinis strain FDAARGOS_770]
MLELQDCLGRIFTENQLEPSLRAQAKEIPSIREEKGKLHCGRCNSLIERENQLPVGAYYCRECLILGRVRSDQKLYYFPQ
EDFPKKQVLKWQGQLTEFQGKVSKGLLDALEKRQNTLVHAVTGAGKTEMIYQVIARVIDRGGSVCLASPRIDVCLELYRR
LKEDFSCEIALLHGESEAYFRSSLVIATTHQLLKFYRAFDLLIVDEVDAFPYVDNPILYHAVERSVKEDATTIFLTATST
DELDKRVQKGELKRLSLPRRFHGNPLTIPQKIWLSDFQKHLQKKKIAPKLLNYIEKQRETQFPLLIFAAEIQRGEDFAHA
LQIALPDEKLAFVASTTENRLEIVEQFRRKEITILVTTTILERGVTFPGVDVFVLEANHRLFSRSALVQISGRVGRSMDR
PTGQLLFFHDGTTLAMEKAIREMRDMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=453484 FOC72_RS01590 WP_002893483.1 326162..327460(+) (comFA/cflA) [Streptococcus sanguinis strain FDAARGOS_770]
ATGTTAGAGTTACAAGATTGTTTAGGACGGATATTTACAGAAAATCAGTTAGAGCCTAGCTTGCGAGCACAAGCAAAAGA
AATTCCCAGTATCCGAGAAGAAAAAGGCAAGCTCCACTGTGGACGCTGCAACAGCTTGATTGAACGAGAAAATCAGCTAC
CTGTTGGAGCTTATTATTGTAGAGAATGCTTAATATTGGGCCGGGTACGGAGTGACCAAAAACTTTACTATTTTCCTCAA
GAGGATTTTCCTAAAAAACAGGTGCTTAAATGGCAGGGGCAACTGACAGAGTTTCAGGGGAAGGTCTCCAAAGGCTTACT
GGATGCGCTAGAGAAAAGACAGAATACGTTAGTGCATGCTGTTACTGGCGCTGGAAAAACAGAAATGATTTACCAAGTGA
TTGCAAGAGTTATTGATAGAGGAGGGTCTGTTTGCTTGGCCAGTCCGCGGATTGATGTTTGTTTAGAACTTTATCGGCGC
CTAAAAGAAGACTTTTCTTGTGAAATAGCCCTTCTGCATGGGGAGTCAGAAGCTTATTTTCGCAGCTCCTTGGTAATTGC
GACCACCCACCAGCTCTTAAAATTTTATCGGGCTTTTGATTTGTTGATTGTGGACGAGGTAGACGCCTTTCCTTATGTGG
ATAATCCCATACTGTATCACGCTGTAGAGCGTTCAGTTAAAGAGGATGCTACAACTATTTTTCTGACAGCCACTTCCACA
GATGAACTGGATAAAAGAGTTCAAAAAGGTGAGTTGAAACGCCTGAGTCTTCCCAGAAGATTTCATGGTAATCCCTTGAC
CATCCCTCAGAAAATTTGGTTATCTGATTTTCAAAAACATCTTCAGAAGAAGAAAATAGCACCTAAACTTTTGAACTATA
TAGAAAAACAGAGGGAGACCCAATTTCCTCTCTTAATATTTGCTGCAGAAATTCAAAGAGGAGAGGATTTTGCTCATGCT
TTGCAGATAGCTCTGCCTGATGAAAAACTGGCTTTTGTCGCCTCCACAACAGAAAATCGCCTAGAGATTGTCGAGCAGTT
TCGTCGCAAGGAGATCACTATTTTGGTGACAACGACTATCTTAGAGCGTGGAGTAACCTTTCCTGGTGTAGATGTTTTTG
TCTTGGAAGCCAATCATCGCCTGTTCAGTCGTAGTGCTCTGGTTCAGATTTCAGGCCGAGTTGGCCGTAGTATGGATAGA
CCGACTGGACAGTTGCTATTTTTTCATGATGGGACTACCCTTGCTATGGAAAAGGCAATTCGGGAAATGAGAGATATGAA
TAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

DEAD/DEAH box helicase (DEAD)

(109-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A859ELX9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

71.194

98.843

0.704
  comFA/cflA Streptococcus pneumoniae D39

71.194

98.843

0.704
  comFA/cflA Streptococcus pneumoniae R6

71.194

98.843

0.704
  comFA/cflA Streptococcus pneumoniae TIGR4

70.96

98.843

0.701
  comFA/cflA Streptococcus mitis NCTC 12261

70.588

98.38

0.694
  comFA/cflA Streptococcus mitis SK321

69.412

98.38

0.683
  comFA Lactococcus lactis subsp. cremoris KW2

55.025

92.13

0.507
  comFA Latilactobacillus sakei subsp. sakei 23K

38.426

100

0.384