Detailed information NTG0453440

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: I6H78_RS04400
• Genome accession: NZ_CP066059
• Coordinates: 917215..918126 (-)
• Length: 303 a.a.
• NCBI ID: WP_198460185.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 912215..923126

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS04360 (I6H78_04360)	-	912328..912894 (-)	567	Protein_854	ABC transporter permease	-
I6H78_RS04365 (I6H78_04365)	-	913364..913864 (-)	501	WP_198460181.1	TlpA family protein disulfide reductase	-
I6H78_RS04370 (I6H78_04370)	-	913854..914228 (-)	375	WP_050235542.1	metalloprotease family protein	-
I6H78_RS04375 (I6H78_04375)	-	914225..914491 (-)	267	WP_050235541.1	hypothetical protein	-
I6H78_RS04380 (I6H78_04380)	-	914478..915833 (-)	1356	WP_198460182.1	hypothetical protein	-
I6H78_RS04385 (I6H78_04385)	-	915790..916506 (-)	717	WP_050235539.1	ATP-binding cassette domain-containing protein	-
I6H78_RS04390 (I6H78_04390)	-	916539..916745 (-)	207	WP_198460183.1	hypothetical protein	-
I6H78_RS04395 (I6H78_04395)	-	916771..917061 (-)	291	WP_198460184.1	hypothetical protein	-
I6H78_RS04400 (I6H78_04400)	comR	917215..918126 (-)	912	WP_198460185.1	helix-turn-helix domain-containing protein	Regulator
I6H78_RS04405 (I6H78_04405)	adhE	918260..920911 (-)	2652	WP_084944770.1	bifunctional acetaldehyde-CoA/alcohol dehydrogenase	-
I6H78_RS04410 (I6H78_04410)	-	921207..921620 (-)	414	WP_198460186.1	MORN repeat-containing protein	-
I6H78_RS04415 (I6H78_04415)	-	921607..922050 (-)	444	WP_198460187.1	low molecular weight protein-tyrosine-phosphatase	-
I6H78_RS04420 (I6H78_04420)	yajC	922098..922418 (-)	321	WP_049501161.1	preprotein translocase subunit YajC	-

Sequence

Protein

• Length: 303 a.a.
• Molecular weight: 35865.06 Da
• Isoelectric Point: 4.7527

>NTDB_id=453440 I6H78_RS04400 WP_198460185.1 917215..918126(-) (comR) [Streptococcus oralis strain FDAARGOS_1021]
MNDLGEKVRLLREEKGLSRPVFCGDESELSVRQLVRIEKGEFRPTIKTLEYIADRLGIPSYVLMPDYKELPKRYQELKYF
LLHHPDYGDKELQEQKEKYFDEIFECFYDDLPRDEKVVVDCLQAIDEVRATSNSLYGSSVIEGGLQDLLSRDVYKAEDLL
KLRLYFNCQLMDGLNVGEIKESEHENILYFHDKLSSQVDKIKFDCLDLLRDSLLASLACIEIMGLFHYFKRAIDTLNKIG
QKTRDFQKQPIVLMVEWKYYIQTDYETAKQKYEEAKMMARMFGNEKLVVSLDNEWTEDLERYR

Nucleotide

• Length: 912 bp

>NTDB_id=453440 I6H78_RS04400 WP_198460185.1 917215..918126(-) (comR) [Streptococcus oralis strain FDAARGOS_1021]
ATGAATGATTTAGGGGAAAAGGTAAGACTCCTTAGAGAGGAGAAAGGTCTTAGTCGTCCAGTTTTTTGTGGAGATGAGTC
AGAGTTATCCGTTCGTCAGTTGGTACGCATTGAAAAAGGAGAATTTCGTCCTACGATAAAAACACTAGAATACATTGCAG
ATAGGCTAGGCATTCCATCCTATGTCTTGATGCCAGACTACAAGGAGTTACCCAAGCGTTACCAAGAATTAAAATACTTT
CTTCTTCATCATCCTGACTATGGAGACAAAGAGTTGCAGGAACAAAAGGAAAAATATTTTGATGAGATTTTTGAGTGTTT
TTATGATGATTTGCCACGTGATGAGAAAGTGGTAGTGGATTGTCTTCAAGCCATAGATGAGGTGAGAGCGACTAGTAATT
CCTTATACGGGAGCAGTGTGATTGAGGGCGGTCTTCAAGACTTACTATCCAGAGATGTATATAAAGCCGAGGACTTGTTG
AAATTGAGACTGTATTTCAACTGTCAGTTAATGGATGGTTTAAATGTGGGTGAGATAAAAGAATCTGAGCATGAAAACAT
TCTTTATTTTCATGATAAACTAAGTTCTCAGGTTGATAAGATAAAGTTCGATTGTTTGGACTTGCTTAGAGATTCCTTGT
TAGCTTCTTTAGCTTGTATAGAAATTATGGGGCTGTTTCATTATTTTAAGAGAGCAATTGACACCTTAAATAAAATAGGG
CAGAAAACACGCGATTTTCAAAAACAACCAATTGTCTTGATGGTGGAGTGGAAATATTATATTCAGACGGATTATGAAAC
AGCAAAACAAAAGTATGAAGAAGCAAAAATGATGGCGAGAATGTTTGGCAATGAGAAATTAGTCGTTAGTTTAGACAATG
AATGGACCGAGGATCTAGAAAGATATCGTTAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (71-295)

• Helix-turn-helix (HTH_3) (9-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.542	99.34	0.373
comR	Streptococcus suis D9	37.049	100	0.373
comR	Streptococcus pyogenes MGAS315	36.013	100	0.37