Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6H78_RS03660 Genome accession   NZ_CP066059
Coordinates   761087..761719 (-) Length   210 a.a.
NCBI ID   WP_198460105.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 756087..766719
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS03645 (I6H78_03645) recD/recD2/recDB 756639..759008 (+) 2370 WP_198460103.1 ATP-dependent RecD-like DNA helicase Machinery gene
  I6H78_RS03650 (I6H78_03650) tig 759056..760339 (-) 1284 WP_000116504.1 trigger factor -
  I6H78_RS03655 (I6H78_03655) - 760430..761086 (-) 657 WP_198460104.1 DNA alkylation repair protein -
  I6H78_RS03660 (I6H78_03660) vraR 761087..761719 (-) 633 WP_198460105.1 response regulator transcription factor Regulator
  I6H78_RS03665 (I6H78_03665) - 761730..762728 (-) 999 WP_198460106.1 sensor histidine kinase -
  I6H78_RS03670 (I6H78_03670) liaF 762725..763423 (-) 699 WP_198460107.1 cell wall-active antibiotics response protein LiaF -
  I6H78_RS03675 (I6H78_03675) fni 763590..764591 (-) 1002 WP_198460108.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  I6H78_RS03680 (I6H78_03680) - 764575..765582 (-) 1008 WP_198460109.1 phosphomevalonate kinase -
  I6H78_RS03685 (I6H78_03685) mvaD 765569..766522 (-) 954 WP_198460110.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23603.18 Da        Isoelectric Point: 4.7229

>NTDB_id=453425 I6H78_RS03660 WP_198460105.1 761087..761719(-) (vraR) [Streptococcus oralis strain FDAARGOS_1021]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=453425 I6H78_RS03660 WP_198460105.1 761087..761719(-) (vraR) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAATTTTACTGGTAGACGACCATGAAATGGTTCGATTGGGCTTGAAAAGCTATTTTGATCTCCAAGACGATGTGGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGACTTGGCCTTGGAACTGCGCCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGATGCTACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAAATCTTGATTGTG
ACCTCTTACTTGGACAATGAAAAAATCATGCCAGTCTTGAATGCTGGTGCCAAAGGCTATATGCTTAAGACTTCAAGTGC
AGATGAATTGCTCCATGCTGTCCGTAAGGTGGCTGCTGGCGAGCTGGCCATTGAACAAGAGGTCAGCAAGAAAGTCGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAACGAGACGTACTTCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGGATTGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAACATCCTAGCCAAACT
TGAGGTCAGTGATCGGACTCAGGCAGCGGTCTATGCCTTCCAGCACCACTTGGTCGGGCAGGAGGAATTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.632

99.524

0.524
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41