Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6I32_RS06135 Genome accession   NZ_CP066041
Coordinates   1262258..1264207 (+) Length   649 a.a.
NCBI ID   WP_198464307.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1257258..1269207
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS06115 (I6I32_06115) argR 1257977..1258423 (+) 447 WP_001231483.1 arginine repressor -
  I6I32_RS06120 (I6I32_06120) hexA 1258474..1261008 (+) 2535 WP_198464304.1 DNA mismatch repair protein MutS Machinery gene
  I6I32_RS06125 (I6I32_06125) - 1261049..1261507 (-) 459 WP_198464305.1 DUF3021 domain-containing protein -
  I6I32_RS06130 (I6I32_06130) - 1261504..1261944 (-) 441 WP_198464306.1 LytTR family DNA-binding domain-containing protein -
  I6I32_RS06135 (I6I32_06135) hexB 1262258..1264207 (+) 1950 WP_198464307.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6I32_RS06140 (I6I32_06140) - 1264361..1264858 (-) 498 WP_198464308.1 helix-turn-helix domain-containing protein -
  I6I32_RS06145 (I6I32_06145) - 1265031..1266263 (+) 1233 WP_000657470.1 MFS transporter -
  I6I32_RS06150 (I6I32_06150) ruvA 1266276..1266869 (+) 594 WP_000273401.1 Holliday junction branch migration protein RuvA Machinery gene
  I6I32_RS06155 (I6I32_06155) - 1266879..1267445 (+) 567 WP_001126061.1 DNA-3-methyladenine glycosylase I -
  I6I32_RS06160 (I6I32_06160) - 1267526..1267789 (-) 264 WP_000166112.1 SemiSWEET family transporter -
  I6I32_RS06165 (I6I32_06165) - 1267895..1268929 (-) 1035 WP_198464309.1 S66 peptidase family protein -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73277.77 Da        Isoelectric Point: 5.6215

>NTDB_id=453247 I6I32_RS06135 WP_198464307.1 1262258..1264207(+) (hexB) [Streptococcus oralis strain FDAARGOS_1075]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSSQIIIEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEAITPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLASAKKMIAIENSDLDFEITGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMALVSE
AISNSLKEQALIPDALENLAKSTVRNRQKVEQTILPLKENTLYYEKTELSRPCQAEVADHQVELTEEGRDLTLFAKETLD
QLTKPAKLHFAERKPANYDQLDHPELDLASLDKAYDKLEREEASSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLRERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=453247 I6I32_RS06135 WP_198464307.1 1262258..1264207(+) (hexB) [Streptococcus oralis strain FDAARGOS_1075]
ATGTCTCATATTATTGAATTGCCAGAGGTGCTGGCAAACCAGATCGCGGCTGGAGAGGTCATTGAACGTCCTGCCAGTGT
AGTCAAAGAGTTGGTAGAAAATGCCATTGACGCGGGTTCTAGCCAGATTATCATTGAGATTGAGGAAGCTGGTCTTAAGA
AGATTCAAATCACAGATAATGGTCATGGAATTGCCCACGATGAGGTGGAATTGGCCTTGCGTCGTCATGCGACCAGTAAG
ATAAAAAATCAAGCAGACCTCTTTCGGATTCGGACGCTCGGATTTCGAGGTGAAGCCCTGCCCTCTATCGCTTCTGTCAG
TGTTCTGACTCTGTTGACGGCGGTGGATGGTGCGAGTCATGGGACCAAGCTCGTTGCGCGTGGGGGTGAAGTCGAAGCAA
TCACTCCTGCGACAAGTCCAGTGGGGACCAAGGTTTGTGTAGAGGACCTCTTTTTCAACACGCCTGCACGTCTCAAGTAT
ATGAAGAGCCAGCAGGCGGAGCTGTCTCATATCATTGATATTGTCAACCGTCTGGGTTTGGCCCATCCAGAGATTTCTTT
TAGTTTGATTAGTGATGGCAAGGAAATGACACGAACAGCTGGTACGGGTCAACTACGCCAAGCTATTGCTGGAATTTATG
GCTTGGCGAGTGCCAAGAAGATGATAGCCATTGAGAATTCGGATCTAGACTTTGAAATTACAGGTTTTGTGTCCTTGCCT
GAGTTGACTCGGGCTAATCGCAACTATATCAGCCTCTTCATCAATGGGCGATATATCAAGAACTTCTTGCTCAATCGTGC
AATTTTGGATGGCTATGGCAGCAAGCTCATGGTGGGCCGTTTTCCACTGGCTGTCATTCACATCCATATCGACCCTTATC
TAGCGGATGTCAATGTGCATCCGACCAAGCAAGAAGTGCGGATTTCTAAGGAAAAAGAACTGATGGCGTTAGTCTCAGAA
GCTATTTCTAACAGTCTCAAAGAGCAAGCCTTGATCCCTGATGCCTTGGAAAATCTTGCCAAGTCGACCGTGCGCAATCG
TCAAAAGGTAGAACAGACCATTCTCCCACTCAAAGAAAATACGCTCTACTATGAAAAAACAGAACTCTCAAGACCTTGTC
AAGCTGAGGTGGCTGATCATCAGGTTGAATTAACTGAGGAAGGTAGGGACTTAACCCTGTTTGCCAAGGAAACCTTGGAC
CAGCTAACCAAGCCCGCAAAACTGCATTTTGCAGAGAGAAAGCCTGCTAACTACGACCAACTAGACCATCCAGAGTTAGA
TCTTGCTAGCCTCGATAAGGCTTATGACAAGCTGGAGCGAGAAGAAGCATCCAGCTTCCCAGAGTTGGAATTTTTCGGAC
AAATGCACGGCACTTATCTCTTTGCCCAGGGGAGAGATGGGCTCTACATCATAGACCAACATGCGGCTCAGGAACGGGTT
AAATACGAGGAATACCGAGAAAGTATTGGCAATGTTGACCAGAGCCAGCAGCAACTCCTAGTGCCCTACATCTTTGAATT
CCCAGCAGATGATGCCCTTCGTCTCAGGGAAAGAATGCCTCTCTTAGAGGAAGTGGGTGTCTTTTTGGCAGAGTACGGAG
AAAATCAATTTATCCTGCGTGAACATCCTATTTGGATGGCAGAGGAAGAGATTGAATCAGGCATCTATGAAATGTGTGAT
ATGCTACTCTTGACCAAGGAAGTTTCTATCAAGAAATACCGAGCAGAGCTGGCAATCATGATGTCCTGCAAGCGGTCTAT
CAAGGCCAACCATCGTATCGATGACCATTCAGCTAGACAACTCCTCTATCAACTCTCTCAATGTGACAATCCTTACAACT
GTCCACATGGCCGTCCTGTTTTGGTACATTTCACCAAGTCGGATATGGAAAAGATGTTCCGACGTATTCAGGAAAATCAT
ACCAGCCTCCGTGAGTTGGGGAAATATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

96.61

100

0.966