Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6I32_RS03585 Genome accession   NZ_CP066041
Coordinates   736983..737615 (-) Length   210 a.a.
NCBI ID   WP_000698402.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1075     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 731983..742615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I32_RS03570 (I6I32_03570) recD/recD2/recDB 732538..734904 (+) 2367 WP_198464939.1 ATP-dependent RecD-like DNA helicase Machinery gene
  I6I32_RS03575 (I6I32_03575) tig 734952..736235 (-) 1284 WP_198464940.1 trigger factor -
  I6I32_RS03580 (I6I32_03580) - 736326..736982 (-) 657 WP_198464941.1 DNA alkylation repair protein -
  I6I32_RS03585 (I6I32_03585) vraR 736983..737615 (-) 633 WP_000698402.1 response regulator Regulator
  I6I32_RS03590 (I6I32_03590) - 737626..738624 (-) 999 WP_198464942.1 sensor histidine kinase -
  I6I32_RS03595 (I6I32_03595) liaF 738621..739319 (-) 699 WP_198464943.1 cell wall-active antibiotics response protein LiaF -
  I6I32_RS03600 (I6I32_03600) fni 739438..740439 (-) 1002 WP_198464944.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  I6I32_RS03605 (I6I32_03605) - 740423..741430 (-) 1008 WP_198464945.1 phosphomevalonate kinase -
  I6I32_RS03610 (I6I32_03610) mvaD 741417..742370 (-) 954 WP_198464946.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23603.18 Da        Isoelectric Point: 4.7177

>NTDB_id=453202 I6I32_RS03585 WP_000698402.1 736983..737615(-) (vraR) [Streptococcus oralis strain FDAARGOS_1075]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIDLALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHALRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=453202 I6I32_RS03585 WP_000698402.1 736983..737615(-) (vraR) [Streptococcus oralis strain FDAARGOS_1075]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTATTTTGATCTCCAAGACGATGTGGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGACTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TCGTCATGCCTGAGATGAATGGGATTGATGCAACCTTGGCCATCCTCAAAGAATGGCCTGAAGCCAAGATATTAATTGTC
ACCTCTTACTTGGACAATGAAAAAATCATGCCAGTCTTGAATGCGGGTGCCAAAGGCTATATGCTTAAGACTTCAAGTGC
AGATGAATTGCTCCATGCTCTCCGTAAGGTGGCTGCTGGCGAGCTGGCTATTGAACAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGTAATCATATGGAGCTTCATGAGGAGCTGACTGCGCGTGAGCGAGACGTACTTCAACTCATCGCCAAGGGCTAC
GAAAATCAGCGGATTGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCATGTGTCCAATATCCTTGCTAAACT
TGAGGTCAGCGATCGCACCCAGGCGGCGGTCTATGCCTTCCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.153

99.524

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405