Detailed information NTG0452829

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: I6H76_RS06835
• Genome accession: NZ_CP065994
• Coordinates: 1329958..1330647 (+)
• Length: 229 a.a.
• NCBI ID: WP_015695709.1
• Uniprot ID: -
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 1324958..1335647

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS06805 (I6H76_06805)	rpmH	1325339..1325473 (+)	135	WP_002885866.1	50S ribosomal protein L34	-
I6H76_RS06810 (I6H76_06810)	-	1325604..1325813 (+)	210	WP_006531845.1	CsbD family protein	-
I6H76_RS06815 (I6H76_06815)	-	1325962..1326135 (+)	174	WP_006531846.1	hypothetical protein	-
I6H76_RS06820 (I6H76_06820)	-	1326261..1327612 (+)	1352	WP_115283723.1	IS3 family transposase	-
I6H76_RS06825 (I6H76_06825)	bglS	1327967..1328683 (+)	717	WP_006530977.1	beta-glucanase	-
I6H76_RS06830 (I6H76_06830)	-	1328842..1329636 (+)	795	WP_006530976.1	helix-turn-helix domain-containing protein	-
I6H76_RS06835 (I6H76_06835)	ciaR	1329958..1330647 (+)	690	WP_015695709.1	response regulator transcription factor	Regulator
I6H76_RS06840 (I6H76_06840)	-	1330641..1331801 (+)	1161	WP_174221238.1	HAMP domain-containing sensor histidine kinase	-
I6H76_RS06845 (I6H76_06845)	-	1331811..1331933 (+)	123	WP_006530973.1	teichoic acid D-Ala incorporation-associated protein DltX	-
I6H76_RS06850 (I6H76_06850)	dltA	1331949..1333487 (+)	1539	WP_006530972.1	D-alanine--poly(phosphoribitol) ligase subunit DltA	-
I6H76_RS06855 (I6H76_06855)	dltB	1333484..1334746 (+)	1263	WP_006530971.1	D-alanyl-lipoteichoic acid biosynthesis protein DltB	-
I6H76_RS06860 (I6H76_06860)	dltC	1334773..1335012 (+)	240	WP_006530970.1	D-alanine--poly(phosphoribitol) ligase subunit DltC	-

Sequence

Protein

• Length: 229 a.a.
• Molecular weight: 26120.41 Da
• Isoelectric Point: 5.0608

>NTDB_id=452829 I6H76_RS06835 WP_015695709.1 1329958..1330647(+) (ciaR) [Streptococcus infantarius strain FDAARGOS_1019]
MRILVVEDEKGIAEAIQAILENHRYEVDLVFDGESALDYILTGLYDLVLLDIMLPKFDGVSVLKRVRQMGMEVPIIFLTA
KSQLEDRVLGLDLGADDYMIKPFEAEELLARIRLRTRQSSITQVNHLKFGNLILNLDTRELSVAEREVKLSNKEFLLMET
FLRNSKKIIPKNQLILKVWGPLDESDYNQLEVFISFLRKKLRFLAASAVIKTTKGVGYSLEDGEKEGSS

Nucleotide

• Length: 690 bp

>NTDB_id=452829 I6H76_RS06835 WP_015695709.1 1329958..1330647(+) (ciaR) [Streptococcus infantarius strain FDAARGOS_1019]
TTGAGAATTTTAGTGGTCGAGGATGAGAAAGGAATCGCGGAAGCTATTCAAGCCATTCTTGAAAATCACCGTTATGAAGT
GGATTTGGTTTTTGATGGTGAGTCTGCACTGGATTATATATTAACGGGACTTTATGATTTGGTTCTTTTGGATATTATGT
TGCCAAAATTTGATGGTGTCAGTGTGTTGAAGCGCGTGCGCCAAATGGGAATGGAAGTTCCTATCATTTTTTTGACAGCC
AAATCTCAGTTAGAAGACCGTGTTTTGGGACTTGATTTGGGTGCTGATGACTATATGATTAAGCCATTTGAGGCAGAAGA
ATTATTGGCACGAATTCGTTTGCGGACTCGTCAATCGTCTATTACGCAAGTGAATCATCTCAAGTTTGGCAATTTGATTT
TGAATCTGGACACGAGAGAATTAAGCGTGGCAGAGCGCGAAGTTAAGTTGTCTAATAAAGAATTTCTGCTGATGGAAACT
TTCTTGCGAAATTCCAAGAAGATTATCCCCAAAAACCAATTAATTTTGAAGGTCTGGGGACCTTTAGATGAATCCGATTA
TAATCAACTGGAAGTCTTTATCTCCTTTTTACGTAAGAAACTTCGTTTCTTGGCAGCCAGTGCTGTTATTAAAACGACCA
AAGGCGTTGGTTACTCACTAGAAGATGGAGAGAAAGAAGGCTCATCATGA

Domains

Predicted by InterProScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (146-220)

• Response regulator receiver domain (Response_reg) (3-113)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	39.64	96.943	0.384
ciaR	Streptococcus pneumoniae D39	39.64	96.943	0.384
ciaR	Streptococcus pneumoniae R6	39.64	96.943	0.384
ciaR	Streptococcus pneumoniae TIGR4	39.64	96.943	0.384
ciaR	Streptococcus mutans UA159	38.565	97.38	0.376