Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   I6H76_RS06130 Genome accession   NZ_CP065994
Coordinates   1181465..1183405 (+) Length   646 a.a.
NCBI ID   WP_006531420.1    Uniprot ID   A0ABM9XFV7
Organism   Streptococcus infantarius strain FDAARGOS_1019     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1176465..1188405
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H76_RS06115 (I6H76_06115) argR 1178004..1178441 (+) 438 WP_006531423.1 arginine repressor -
  I6H76_RS06120 (I6H76_06120) - 1178438..1178791 (+) 354 WP_006531422.1 YlbF family regulator -
  I6H76_RS06125 (I6H76_06125) hexA 1178778..1181345 (+) 2568 WP_006531421.1 DNA mismatch repair protein MutS Machinery gene
  I6H76_RS06130 (I6H76_06130) hexB 1181465..1183405 (+) 1941 WP_006531420.1 DNA mismatch repair endonuclease MutL Machinery gene
  I6H76_RS06135 (I6H76_06135) ruvA 1183406..1183999 (+) 594 WP_006531419.1 Holliday junction branch migration protein RuvA Machinery gene
  I6H76_RS06140 (I6H76_06140) - 1184029..1184586 (+) 558 WP_043878298.1 DNA-3-methyladenine glycosylase I -
  I6H76_RS06145 (I6H76_06145) - 1184709..1185911 (+) 1203 WP_006531417.1 MFS transporter -
  I6H76_RS06150 (I6H76_06150) cinA 1186025..1187284 (+) 1260 WP_006531416.1 competence/damage-inducible protein A Machinery gene

Sequence

Protein


Download         Length: 646 a.a.        Molecular weight: 73062.23 Da        Isoelectric Point: 5.5682

>NTDB_id=452823 I6H76_RS06130 WP_006531420.1 1181465..1183405(+) (hexB) [Streptococcus infantarius strain FDAARGOS_1019]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKNIQVTDNGEGISQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADEHYGTLLVAKGGEIERQEAISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMGLISS
AIAESLREQDLIPDALENLAKSSTRGFSKPQQTSLPLKQTNLYYDKERHDFFVKSDTVEEEPAQLFNEVDKAVKQVDKQS
SVRYAQRSLAGQAYDEHDDLDFKNKTKINRMIESLDKEEVSTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERVKYE
YYRDKIGEVDDSLQQLLMPYLFEFSGADFIKIQEKMELLKQVGINLEPYGNNTFILREHPIWMKEEEIETAVYEMCDMLL
LTNGVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLIVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSL
RELGKY

Nucleotide


Download         Length: 1941 bp        

>NTDB_id=452823 I6H76_RS06130 WP_006531420.1 1181465..1183405(+) (hexB) [Streptococcus infantarius strain FDAARGOS_1019]
ATGAGCAAAATTATTGAGTTGCCAGAGGTTTTGGCCAACCAGATTGCTGCAGGTGAAGTGATTGAACGACCGGCCAGTGT
GGTTAAAGAATTGGTTGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACCATCGAGATTGAAGAATCAGGTCTTAAGA
ATATTCAAGTCACTGATAATGGTGAGGGAATTTCTCAAGAGGATGTGGCTTTAAGTTTGCATCGCCATGCTACAAGTAAG
ATTAAAAGCCAAGCTGACCTTTTTCGTATCAGAACTTTGGGATTCCGCGGTGAGGCCATTCCTTCCATTGCCTCAATTAG
CCACTTTACAGTGAAAACAGCGACTGCTGATGAACACTATGGAACGCTTTTAGTGGCAAAGGGGGGCGAGATTGAGCGAC
AAGAAGCAATTTCAACACCTGTCGGGACAAAAATTACCGTTGAAAATCTTTTTTACAACACTCCTGCTCGTCTCAAATAT
ATGAAGAGCTTGCAATCAGAGTTGGCTCATATCGTTGATGTGGTTAATCGCTTGAGCCTAGCTCACCCAGAAATTGCCTT
TACTTTGATTAATGATGGTCGTCAAATGACAACGACTTCTGGGACAGGTGATTTGCGTCAAGCCATCGCTGGTATTTACG
GTTTAAATACAGCTAAGAAAATGATTGAAATCTCAAATGCTGACCTTGATTTTGAAGTCTCAGGTTATATTAGTTTACCA
GAATTGACGCGTGCAAATCGCAATTACATTACCATTTTAATTAATGGTCGCTACATCAAAAACTTCTTGCTCAACCGTGC
GATTTTGGATGGTTATGGATCAAAATTGATGGTTGGTCGTTTCCCAATTGCGGTCATTGACATTCAAATCGACCCTTATC
TTGCCGATGTCAATGTTCACCCAACTAAACAAGAAGTTCGTATCTCAAAAGAAAAAGAACTCATGGGCTTAATTAGCTCA
GCTATTGCAGAGAGTTTGCGTGAGCAAGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGTACTCGAGGTTT
TTCAAAACCTCAGCAAACGAGTCTGCCTTTAAAACAAACCAACCTTTACTATGATAAGGAACGTCACGATTTCTTTGTGA
AATCAGATACGGTTGAAGAAGAGCCAGCGCAGTTATTTAATGAGGTTGACAAAGCTGTCAAGCAAGTTGACAAGCAATCT
TCAGTTAGGTATGCACAGCGTTCATTGGCAGGTCAAGCGTATGATGAGCATGATGATCTTGATTTTAAAAATAAAACGAA
AATCAATCGCATGATTGAAAGTCTTGATAAGGAGGAAGTTTCTACTTTCCCTGAGTTAGAGTACTTTGGGCAAATGCACG
GCACTTATCTTTTTGCGCAAGGCAATGGTGGGCTTTATATCATTGACCAGCATGCGGCTCAGGAACGTGTCAAGTATGAG
TATTATCGTGACAAAATTGGCGAAGTTGATGATTCATTACAACAGTTGCTGATGCCATATCTATTTGAGTTTTCTGGGGC
AGATTTCATCAAAATTCAAGAAAAAATGGAGCTTCTAAAGCAAGTTGGCATTAATTTAGAACCATACGGCAATAATACTT
TTATCCTTCGCGAGCATCCTATTTGGATGAAGGAAGAGGAGATTGAGACAGCTGTTTATGAAATGTGCGACATGTTGCTG
TTGACCAATGGAGTTTCTGTCAAGAAATACCGCGCTGAGTTAGCGATTATGATGTCATGTAAACGATCAATCAAGGCTAA
CCATACACTTGATGACTATTCAGCCCGACAACTCATTGTTCAATTATCTCAATGTAAGAACCCTTATAACTGCCCACACG
GACGTCCAGTACTTGTTAATTTTACCAAGTCAGACATGGAAAAAATGTTCCGTCGTATTCAAGAAAATCACACAAGTTTA
AGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(448-590)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.771

100

0.707