Detailed information NTG0452822

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: I6H76_RS06125
• Genome accession: NZ_CP065994
• Coordinates: 1178778..1181345 (+)
• Length: 855 a.a.
• NCBI ID: WP_006531421.1
• Uniprot ID: A0ABM9XFU2
• Organism: Streptococcus infantarius strain FDAARGOS_1019
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1173778..1186345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H76_RS06100 (I6H76_06100)	-	1174263..1175681 (+)	1419	WP_006531427.1	prolyl oligopeptidase family serine peptidase	-
I6H76_RS10090	-	1175710..1175901 (-)	192	WP_006531426.1	bacteriocin immunity protein	-
I6H76_RS06110 (I6H76_06110)	argS	1176123..1177814 (-)	1692	WP_006531424.1	arginine--tRNA ligase	-
I6H76_RS06115 (I6H76_06115)	argR	1178004..1178441 (+)	438	WP_006531423.1	arginine repressor	-
I6H76_RS06120 (I6H76_06120)	-	1178438..1178791 (+)	354	WP_006531422.1	YlbF family regulator	-
I6H76_RS06125 (I6H76_06125)	hexA	1178778..1181345 (+)	2568	WP_006531421.1	DNA mismatch repair protein MutS	Machinery gene
I6H76_RS06130 (I6H76_06130)	hexB	1181465..1183405 (+)	1941	WP_006531420.1	DNA mismatch repair endonuclease MutL	Machinery gene
I6H76_RS06135 (I6H76_06135)	ruvA	1183406..1183999 (+)	594	WP_006531419.1	Holliday junction branch migration protein RuvA	Machinery gene
I6H76_RS06140 (I6H76_06140)	-	1184029..1184586 (+)	558	WP_043878298.1	DNA-3-methyladenine glycosylase I	-
I6H76_RS06145 (I6H76_06145)	-	1184709..1185911 (+)	1203	WP_006531417.1	MFS transporter	-

Sequence

Protein

• Length: 855 a.a.
• Molecular weight: 96033.19 Da
• Isoelectric Point: 4.8914

>NTDB_id=452822 I6H76_RS06125 WP_006531421.1 1178778..1181345(+) (hexA) [Streptococcus infantarius strain FDAARGOS_1019]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKNFGLAYMDVSTGEFYATSLSDFTS
LKSEILNLKAREIVVGYDLSEDEQHSLVKQLNLLLSFEQERYEDVHLIDLNLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQEQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFDSPYLDKLVNSIDTLPELESLISSAIDP
DAQAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPSFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASEKSLILFDELGRGTATYDGMALAQSIIEYIHDHIRAKTMFATHYHEL
TSLSTALTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRANSILTNLESGAAQLHLTAETEEK
TQVKTEAAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2568 bp

>NTDB_id=452822 I6H76_RS06125 WP_006531421.1 1178778..1181345(+) (hexA) [Streptococcus infantarius strain FDAARGOS_1019]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTCAAAAAAGACTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTACGAACTATTTTATGAGGATGCTGTTAAGGCGGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCTATTCCAATGGCTGGTGTTCCTTATCATTCAGCCCAACAATACATTGATGTCTTAGTT
GAGATGGGGTATAAGGTTGCCATTGCTGAGCAGATGGAAGATCCGAAGCAGGCAGTTGGTGTGGTTAAGCGTGAAGTCGT
TCAGGTGATTACACCAGGGACAGCGGTTGATTCTTCTAAGCCAGATAATGCTAATAATTTCTTGGTAGCTATTGATTCTG
ATGGCAAAAACTTTGGTTTGGCTTATATGGATGTGTCAACGGGTGAGTTTTACGCGACAAGTTTGTCTGATTTTACAAGC
CTAAAAAGTGAGATTTTAAACCTCAAGGCTCGTGAAATCGTGGTTGGTTATGACCTTTCTGAAGATGAGCAACACAGCTT
GGTTAAACAACTCAATCTCTTATTATCGTTTGAGCAAGAGCGCTATGAAGATGTGCATTTGATTGACCTGAATTTAACAG
CGTTAGAGATTTCTGCTGCTGAAAAATTACTTCAATACGTTCATACGACACAAAAACGTGAACTCAGTCACCTGCAAAAG
CTGGTTCACTATGAAATCAAAGACTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTACTAGAAAATGCCCG
CACAAGCAAGAAGCACGGTAGTCTTTACTGGTTGCTTGATGAAACTAAGACGGCTATGGGGATGCGTTTGTTGCGTAACT
GGATTGATCGTCCATTGGTTAATCAAGAACAAATTGAGGAACGCCAAAATATTGTCCAAGTTTTCTTAGACAACTTCTTT
GAACGTAGTGATTTGACGGACAGTCTAAAAGGCGTTTATGATATTGAGCGTTTGGCTAGTCGTGTGTCATTTGGAAAAGC
CAATCCAAAAGATTTGCTTCAACTTGGTCACACTTTGGGACAAGTGCCAACTATTAAAGCTATCTTGGAATCTTTTGATA
GTCCTTACCTTGACAAGCTTGTCAACAGCATTGACACTTTACCAGAGCTAGAGTCATTGATTAGCTCTGCTATTGACCCA
GATGCTCAAGCAGTGATTACGGAAGGAAGTATTATCAGAACTGGTTTTGATGAGACTTTGGACAAATATCGTAAAGTCAT
GCGCGAAGGGACAAGCTGGATTGCTGAGATTGAAGCCAAAGAACGTGCGGCAAGTGGTATTACAAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTACTATTTCCATGTAACAAATTCTAACCTTTCTTTGGTGCCAGATTACTTCTTCCGTAAAGCA
ACTTTGAAGAATTCAGAGCGTTTTGGTACGGCAGAATTAGCTAAAATTGAAGGTGAAATGCTTGAGGCGCGTGAGCAATC
AGCGAGTCTGGAATACGATATTTTCATGCGCGTTCGCGCACAGGTGGAACGTTATATTTCACGTCTGCAAGATTTGGCAA
AAGCTATTTCTACAGTCGATGTTCTGCAAAGTTTGGCAGTGGTTGCGGAAAACAACCATTATGTTCGTCCAAGCTTTAAT
GATAGCCATGAAATAAAGATTGAAAAAGGTCGCCATGCGGTTGTTGAAAAAGTCATGGGTACGCAAGAATATATCCCAAA
TACCATCACATTTGGCAGAAATACTAATATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAGTCAACTTATATGCGTC
AGTTAGCTTTGACGGTTATCATGGCGCAGATGGGGTCATACGTTGCTGCTGAGAGTGTCAGTCTTCCCGTTTTTGATGCG
ATTTTCACACGTATTGGTGCGGCGGATGATTTGATTTCAGGTCAATCAACCTTTATGGTGGAAATGATGGAAGCCAACCA
AGCCATCAAACGAGCCAGTGAAAAATCTTTGATTCTCTTTGATGAATTGGGACGCGGGACAGCAACTTACGATGGAATGG
CTTTAGCACAATCTATTATTGAGTATATCCACGATCACATTCGTGCTAAGACCATGTTTGCGACCCATTATCATGAGTTG
ACATCGCTGTCAACTGCCTTGACACACCTTGTCAACGTCCATGTTGCAACGCTTGAACGTAATGGTGATGTGACTTTCCT
TCATAAAATCGCAGAAGGACCAGCTGACAAATCTTATGGTATTCACGTTGCGAAAATTGCAGGTTTGCCAGAAGATTTGT
TGCAACGAGCAAATAGTATTTTAACCAATCTCGAATCAGGTGCTGCGCAGCTTCATTTGACAGCAGAAACTGAAGAGAAA
ACTCAAGTGAAGACAGAAGCGGCAGAACCTGTTGCAGAGCAGCTTAGCTTATTTGCAGATGACTCAAGTAACCAAGAAGT
GATTGAAGCTCTTAAAAAAGTGGACTTGATGAATCTAACACCAATGCAAGCTATGAATGTCATTTATGAATTGAAAAACA
TGTTATAA

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (256-546)

• MutS domain I (MutS_I) (8-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	72.982	100	0.73
mutS	Pseudomonas stutzeri strain ATCC 17587	37.14	100	0.377