Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   I6I15_RS14750 Genome accession   NZ_CP065970
Coordinates   2990623..2991279 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain FDAARGOS_1058     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2985623..2996279
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6I15_RS14720 (I6I15_14720) dcyD 2986502..2987488 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  I6I15_RS14725 (I6I15_14725) tcyL 2987503..2988171 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  I6I15_RS14730 (I6I15_14730) tcyN 2988168..2988920 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  I6I15_RS14735 (I6I15_14735) sdiA 2989150..2989872 (+) 723 WP_001152713.1 transcriptional regulator SdiA -
  I6I15_RS14740 (I6I15_14740) yecF 2989940..2990164 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  I6I15_RS14745 (I6I15_14745) yecU 2990151..2990327 (-) 177 WP_000590344.1 protein YecU -
  I6I15_RS26585 - 2990365..2990481 (-) 117 Protein_2781 transcriptional regulator -
  I6I15_RS14750 (I6I15_14750) letA 2990623..2991279 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  I6I15_RS14755 (I6I15_14755) uvrC 2991276..2993108 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  I6I15_RS14760 (I6I15_14760) pgsA 2993165..2993713 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  I6I15_RS14780 (I6I15_14780) yecA 2994363..2995028 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=452579 I6I15_RS14750 WP_000611335.1 2990623..2991279(+) (letA) [Escherichia coli strain FDAARGOS_1058]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=452579 I6I15_RS14750 WP_000611335.1 2990623..2991279(+) (letA) [Escherichia coli strain FDAARGOS_1058]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486