Detailed information NTG0450734

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: I6G43_RS05220
• Genome accession: NZ_CP065706
• Coordinates: 1090755..1092104 (+)
• Length: 449 a.a.
• NCBI ID: WP_038806132.1
• Uniprot ID: -
• Organism: Streptococcus oralis strain FDAARGOS_886
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1085755..1097104

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS05195 (I6G43_05195)	-	1086005..1086823 (+)	819	WP_038806136.1	NAD kinase	-
I6G43_RS05200 (I6G43_05200)	-	1086820..1087716 (+)	897	WP_038806135.1	RluA family pseudouridine synthase	-
I6G43_RS05205 (I6G43_05205)	pta	1087760..1088734 (+)	975	WP_038806134.1	phosphate acetyltransferase	-
I6G43_RS05210 (I6G43_05210)	mutY	1088820..1089998 (+)	1179	WP_038806133.1	A/G-specific adenine glycosylase	-
I6G43_RS05215 (I6G43_05215)	yycF	1090055..1090762 (+)	708	WP_000723165.1	response regulator YycF	-
I6G43_RS05220 (I6G43_05220)	micB	1090755..1092104 (+)	1350	WP_038806132.1	cell wall metabolism sensor histidine kinase VicK	Regulator
I6G43_RS05225 (I6G43_05225)	vicX	1092106..1092915 (+)	810	WP_038806131.1	MBL fold metallo-hydrolase	Regulator
I6G43_RS05230 (I6G43_05230)	-	1092953..1093300 (-)	348	WP_038806130.1	thiol reductase thioredoxin	-
I6G43_RS05235 (I6G43_05235)	-	1093411..1095129 (-)	1719	WP_038806129.1	phospho-sugar mutase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51623.14 Da
• Isoelectric Point: 4.6847

>NTDB_id=450734 I6G43_RS05220 WP_038806132.1 1090755..1092104(+) (micB) [Streptococcus oralis strain FDAARGOS_886]
MIEDIRQTILTSDFIFILILLGFILVVTLLLLENRRDNIRLKQVNQKIKDLIAGDYSRVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQETKRLNSILSYMTDGVLATNRRGQITMINDMAKKQLGVVKEEALNKSILELLKIEDEYELRDLITQIPE
LMIDSQNANGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALY
DPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATTQLDVELINFTAFITFILNRFDKMRSQDEEKKYELVRDYPINSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTEDQMILSIKDQGLGIPKQDLPKIFDRFYRVDRARSRAQGGTGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKEEVWEDEVED

Nucleotide

• Length: 1350 bp

>NTDB_id=450734 I6G43_RS05220 WP_038806132.1 1090755..1092104(+) (micB) [Streptococcus oralis strain FDAARGOS_886]
ATGATTGAAGATATTAGACAAACGATTCTGACCAGTGATTTTATCTTTATCCTGATTTTACTTGGCTTTATCTTGGTGGT
AACCTTGTTGTTACTGGAAAATCGTCGGGATAATATTCGTCTAAAGCAGGTTAATCAAAAGATTAAAGATTTGATTGCAG
GGGATTATTCTCGAGTATTGGATATGCAGGGAAGCTCTGAAATCACCAACATCACCAATAATCTTAATGACTTGTCTGAG
GTCATTCGTTTAACGCAGGAGAATTTGGAGCAAGAAACAAAAAGGCTTAACAGTATTCTTTCTTATATGACAGATGGAGT
ACTAGCGACCAATCGCCGTGGTCAAATTACCATGATTAACGATATGGCCAAGAAACAGCTGGGTGTCGTAAAAGAAGAAG
CATTGAACAAAAGCATCCTAGAATTGCTTAAGATAGAGGATGAATATGAACTGCGTGACCTCATTACACAGATTCCTGAA
TTGATGATTGATTCCCAAAATGCTAATGGAGAATATCTTAGTCTTCGTGTGCGTTTTGCACTCATTCGTCGTGAGTCTGG
ATTCATTTCTGGTTTGGTTGCCGTTTTGCACGATACGACTGAACAGGAGAAGGAAGAGCGTGAACGGAGACTCTTCGTGT
CTAATGTTAGCCATGAGTTGCGGACACCTTTGACTAGTGTTAAGTCCTATCTTGAAGCCTTAGACGAGGGAGCCTTGTAT
GATCCTGTTGCTCCTGATTTTATCAAGGTTTCGCTCGATGAAACCAACCGTATGATGCGGATGGTGACAGATCTCTTGCA
TCTCTCTCGTATTGATAATGCGACCACTCAGTTGGATGTGGAATTGATTAATTTTACGGCCTTCATTACCTTTATCCTCA
ACCGCTTTGATAAGATGAGAAGTCAGGATGAGGAGAAAAAATATGAGCTGGTTAGAGATTACCCAATCAACTCAGTTTGG
ATCGAGATTGATACCGATAAAATGACTCAGGTGATTGATAATATTCTTAACAATGCCATCAAGTACTCACCAGATGGTGG
GAAAATTACTGTCAGCATGAAAACCACTGAAGACCAGATGATTTTATCTATCAAAGACCAAGGTCTAGGTATTCCAAAAC
AAGATTTGCCGAAGATTTTTGACCGCTTTTACCGTGTGGATCGTGCAAGAAGTCGTGCTCAAGGTGGAACTGGTCTAGGT
CTGGCTATTGCCAAGGAAATCATCAAACAACACAATGGCTTTATTTGGGCCAAAAGTGAATACGGTAAGGGGTCAACCTT
TACCATTGTGCTCCCTTATGATAAGGAGGCAGTGAAAGAAGAAGTCTGGGAGGATGAAGTAGAAGACTAG

Domains

Predicted by InterProScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• PAS fold (PAS) (95-198)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	89.066	97.773	0.871
vicK	Streptococcus mutans UA159	70.398	89.532	0.63