Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I6G43_RS02415 Genome accession   NZ_CP065706
Coordinates   510731..511363 (+) Length   210 a.a.
NCBI ID   WP_038806398.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_886     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 505731..516363
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G43_RS02390 (I6G43_02390) mvaD 505928..506881 (+) 954 WP_000375371.1 diphosphomevalonate decarboxylase -
  I6G43_RS02395 (I6G43_02395) - 506868..507875 (+) 1008 WP_000562385.1 phosphomevalonate kinase -
  I6G43_RS02400 (I6G43_02400) fni 507859..508860 (+) 1002 WP_000210660.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  I6G43_RS02405 (I6G43_02405) liaF 509027..509725 (+) 699 WP_000714478.1 cell wall-active antibiotics response protein LiaF -
  I6G43_RS02410 (I6G43_02410) - 509722..510720 (+) 999 WP_000744939.1 sensor histidine kinase -
  I6G43_RS02415 (I6G43_02415) vraR 510731..511363 (+) 633 WP_038806398.1 response regulator Regulator
  I6G43_RS02420 (I6G43_02420) - 511364..512020 (+) 657 WP_038806397.1 DNA alkylation repair protein -
  I6G43_RS02425 (I6G43_02425) tig 512113..513396 (+) 1284 WP_038806396.1 trigger factor -
  I6G43_RS02430 (I6G43_02430) recD/recD2/recDB 513444..515810 (-) 2367 WP_038806395.1 ATP-dependent RecD-like DNA helicase Machinery gene

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23545.14 Da        Isoelectric Point: 4.8013

>NTDB_id=450705 I6G43_RS02415 WP_038806398.1 510731..511363(+) (vraR) [Streptococcus oralis strain FDAARGOS_886]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIELALELRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSAGELLHAVRKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=450705 I6G43_RS02415 WP_038806398.1 510731..511363(+) (vraR) [Streptococcus oralis strain FDAARGOS_886]
ATGAAAATTTTACTGGTAGATGACCATGAAATGGTCCGATTGGGCTTGAAAAGCTATTTTGACCTCCAAGACGATGTAGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGAGTTGGCCTTGGAACTGCGTCCAGATGTCATTGTCATGGATA
TTGTCATGCCTGAGATGAATGGGATTGACGCGACCTTGGCTATCCTCAAAGAATGGCCTGAAGCCAAAATCTTGATTGTG
ACCTCTTACTTGGACAATGAAAAAATCATGCCGGTCTTGAACGCTGGTGCCAAAGGTTATATGCTCAAGACTTCTAGTGC
AGGTGAACTACTCCATGCTGTTCGTAAGGTGGCTGCTGGCGAGTTGGCCATTGAGCAAGAGGTCAGCAAGAAGGTCGAAT
ACCACCGCAATCATATGGAACTTCATGAGGAATTGACTGCTCGTGAACGTGACGTGCTTCAACTGATCGCCAAGGGCTAT
GAAAATCAGCGCATCGCAGATGAACTCTTTATCTCTCTCAAGACGGTCAAGACCCACGTGTCCAACATCCTTGCCAAGCT
TGAGGTCAGTGATCGCACCCAGGCTGCGGTCTATGCCTTCCAGCACCACTTGGTCGGGCAGGAGGACTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-114)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.632

99.524

0.524
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405