Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I6G44_RS10720 Genome accession   NZ_CP065702
Coordinates   2125910..2127352 (-) Length   480 a.a.
NCBI ID   WP_197932575.1    Uniprot ID   -
Organism   Lactococcus lactis strain FDAARGOS_887     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2120910..2132352
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6G44_RS10695 (I6G44_10695) nox 2120942..2122282 (+) 1341 WP_021214845.1 H2O-forming NADH oxidase -
  I6G44_RS10700 (I6G44_10700) - 2122372..2122761 (+) 390 WP_010905314.1 single-stranded DNA-binding protein -
  I6G44_RS10705 (I6G44_10705) groES 2122881..2123165 (+) 285 WP_197932640.1 co-chaperone GroES -
  I6G44_RS10710 (I6G44_10710) groL 2123253..2124881 (+) 1629 WP_197932574.1 chaperonin GroEL -
  I6G44_RS10715 (I6G44_10715) vicX 2124927..2125739 (-) 813 WP_003131583.1 MBL fold metallo-hydrolase Regulator
  I6G44_RS10720 (I6G44_10720) vicK 2125910..2127352 (-) 1443 WP_197932575.1 sensor histidine kinase Regulator
  I6G44_RS10725 (I6G44_10725) yycF 2127345..2128046 (-) 702 WP_003131580.1 response regulator YycF -
  I6G44_RS10730 (I6G44_10730) tmk 2128224..2128859 (+) 636 WP_003131575.1 dTMP kinase -
  I6G44_RS10735 (I6G44_10735) - 2128992..2129852 (+) 861 WP_003131573.1 DNA polymerase III subunit delta' -
  I6G44_RS10740 (I6G44_10740) yaaT 2129904..2130686 (+) 783 WP_010905316.1 stage 0 sporulation family protein Regulator
  I6G44_RS10745 (I6G44_10745) yabA 2130679..2131005 (+) 327 WP_010905317.1 DNA replication initiation control protein YabA -
  I6G44_RS10750 (I6G44_10750) rsmI 2131005..2131880 (+) 876 WP_197932576.1 16S rRNA (cytidine(1402)-2'-O)-methyltransferase -
  I6G44_RS10755 (I6G44_10755) - 2131957..2132148 (-) 192 WP_003131566.1 hypothetical protein -

Sequence

Protein


Download         Length: 480 a.a.        Molecular weight: 54743.19 Da        Isoelectric Point: 4.5889

>NTDB_id=450647 I6G44_RS10720 WP_197932575.1 2125910..2127352(-) (vicK) [Lactococcus lactis strain FDAARGOS_887]
MIKFFNSMIFKGVVAHLLLFVILFMSSFDYNFAHLSTFIGYYLFSLVFVLVFLNQQHRMIVNVSKQMNDIKNGYLNRDKI
PKGTSEINELYDEILKLGEDIVRTQNNLENQRNQLDSILAYMVDGVIATDRRGNIIMANKSALHYLNTDNDLLMQKNIVE
VLKITDQYNFYDLLEKEPEITIETHDSGNESISLHIKFALFRRESGFISGIIAVLHDMTEQDKAERERRLFVSNVSHELR
TPLTSVKAYLEALEDGAIEDKETASSFINVSLTETNRMIRMISDLLTLSRMDQDRIVLNKEMINLIAFLDYQINRLDQIL
ETESNDLISSNFTLVRKYSEQPIWVEIDTDKIAQVIDNIIGNAIKYSPKGGTITISVEKRESDVLISISDQGMGIPKSDL
LKIFDRFYRVDNASRNSKVGGTGLGLSIVHDIFKIHGGTIFASSEGEGKGTTFSFTLPYSLEAADDWDDGTDEFEFEDNE

Nucleotide


Download         Length: 1443 bp        

>NTDB_id=450647 I6G44_RS10720 WP_197932575.1 2125910..2127352(-) (vicK) [Lactococcus lactis strain FDAARGOS_887]
ATGATTAAATTTTTTAATTCAATGATTTTTAAAGGAGTAGTTGCACACCTACTTCTTTTTGTCATCCTTTTTATGAGCAG
TTTTGATTACAATTTTGCTCATTTAAGTACTTTTATTGGTTATTACTTATTTTCACTCGTCTTTGTTTTAGTCTTTCTCA
ATCAGCAACATCGCATGATTGTGAATGTTTCTAAACAGATGAATGACATAAAAAATGGCTATTTAAATCGCGATAAAATC
CCAAAAGGGACGAGTGAAATCAATGAATTATATGATGAAATTTTAAAACTTGGTGAAGATATTGTTCGCACGCAGAACAA
TCTTGAAAATCAGCGTAATCAATTAGATAGTATTCTCGCATATATGGTTGATGGCGTCATTGCCACCGATCGTCGTGGAA
ATATTATTATGGCCAATAAATCAGCTTTGCACTATTTGAATACAGATAATGATCTCTTGATGCAAAAAAATATTGTTGAA
GTTTTAAAAATTACTGACCAATATAATTTTTATGATTTATTAGAAAAAGAACCTGAAATAACTATTGAGACACATGATTC
TGGGAATGAATCCATTTCGCTCCACATTAAATTTGCCCTCTTTCGTCGTGAATCTGGTTTCATCTCAGGAATTATTGCCG
TCTTACATGATATGACTGAACAAGACAAGGCCGAACGAGAGCGCCGTCTCTTTGTTTCCAATGTTTCTCATGAACTCCGA
ACTCCGCTCACCTCAGTAAAAGCCTACTTGGAAGCACTAGAAGACGGAGCCATTGAGGATAAAGAAACAGCTTCATCCTT
TATTAATGTTTCACTTACTGAAACTAATCGGATGATTCGAATGATTTCCGACCTTTTGACTTTATCAAGAATGGATCAAG
ACCGAATCGTTCTTAATAAAGAAATGATTAATTTAATTGCCTTCTTAGACTATCAAATTAACCGTTTAGACCAAATTTTA
GAAACCGAATCAAACGATTTAATCTCTTCTAATTTCACTCTAGTCAGAAAATACTCTGAACAGCCCATCTGGGTCGAAAT
TGATACCGATAAAATTGCTCAAGTCATTGACAATATCATCGGAAATGCAATTAAGTATTCACCTAAAGGTGGAACTATTA
CAATTTCCGTTGAAAAACGTGAAAGTGATGTTCTAATCTCCATCAGTGACCAAGGAATGGGGATTCCAAAATCTGATTTA
CTTAAGATTTTTGACCGTTTCTACCGAGTTGATAATGCTTCAAGAAATTCAAAAGTTGGGGGGACAGGTTTAGGCCTCTC
TATTGTCCATGATATTTTTAAAATACATGGCGGAACAATTTTTGCAAGTTCTGAAGGAGAAGGAAAAGGAACGACCTTTA
GTTTCACTCTTCCATATTCTTTAGAAGCCGCAGATGACTGGGATGATGGCACTGATGAGTTTGAATTTGAGGATAATGAA
TAA

Domains

Predicted by InterProScan.

PAS domain (PAS_9)

(124-220)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(348-459)

His Kinase A (phospho-acceptor) domain (HisKA)

(228-293)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

51.319

86.875

0.446
  micB Streptococcus pneumoniae Cp1015

47.748

92.5

0.442