Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FOC62_RS05290 Genome accession   NZ_CP054017
Coordinates   1029292..1029921 (-) Length   209 a.a.
NCBI ID   WP_002452289.1    Uniprot ID   A0A2T4Q1G3
Organism   Staphylococcus warneri strain FDAARGOS_754     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1024292..1034921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC62_RS05260 (FOC62_05265) - 1024822..1025352 (-) 531 WP_002452295.1 acyl-CoA thioesterase -
  FOC62_RS05265 (FOC62_05270) - 1025411..1026652 (-) 1242 WP_002452294.1 aminopeptidase -
  FOC62_RS05270 (FOC62_05275) - 1026665..1026868 (-) 204 WP_002452293.1 DUF1128 domain-containing protein -
  FOC62_RS05275 (FOC62_05280) - 1027015..1027479 (+) 465 WP_002452292.1 low molecular weight protein-tyrosine-phosphatase -
  FOC62_RS05280 (FOC62_05285) - 1027486..1027770 (+) 285 WP_002452291.1 hypothetical protein -
  FOC62_RS05285 (FOC62_05290) - 1027999..1029234 (+) 1236 WP_002452290.1 YihY/virulence factor BrkB family protein -
  FOC62_RS05290 (FOC62_05295) vraR 1029292..1029921 (-) 630 WP_002452289.1 two-component system response regulator VraR Regulator
  FOC62_RS05295 (FOC62_05300) vraS 1029911..1030954 (-) 1044 WP_002452288.1 sensor histidine kinase Regulator
  FOC62_RS05300 (FOC62_05305) liaF 1030951..1031652 (-) 702 WP_002452287.1 cell wall-active antibiotics response protein LiaF -
  FOC62_RS05305 (FOC62_05310) - 1031667..1032053 (-) 387 WP_002452286.1 DUF2543 family protein -
  FOC62_RS05310 (FOC62_05315) map 1032197..1032952 (-) 756 WP_002452285.1 type I methionyl aminopeptidase -
  FOC62_RS05315 (FOC62_05320) - 1033116..1034105 (+) 990 WP_002452284.1 aromatic acid exporter family protein -
  FOC62_RS05320 (FOC62_05325) - 1034160..1034885 (-) 726 WP_002452283.1 type 1 glutamine amidotransferase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23571.16 Da        Isoelectric Point: 4.8917

>NTDB_id=450196 FOC62_RS05290 WP_002452289.1 1029292..1029921(-) (vraR) [Staphylococcus warneri strain FDAARGOS_754]
MAIKVLFVDDHEMVRIGISSYLSTQSDIEVVGEGESGKDAIAKAHELQPDLILMDLLMDDMDGVEATTEIKKDLPHIKVV
MLTSFIEDKEVYRALDAGVDSYILKTTSASDIAEAVRKTYHGESVFEPEVLVKMRNRMKKRAELYEMLTDREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=450196 FOC62_RS05290 WP_002452289.1 1029292..1029921(-) (vraR) [Staphylococcus warneri strain FDAARGOS_754]
ATGGCGATTAAAGTATTATTTGTAGACGACCATGAGATGGTTAGAATAGGTATTTCAAGTTACTTATCAACACAATCTGA
CATTGAAGTAGTGGGAGAAGGTGAGTCTGGGAAAGATGCAATTGCAAAGGCACATGAGTTACAACCAGATTTGATTCTAA
TGGATTTACTTATGGATGATATGGATGGTGTAGAAGCGACAACAGAAATTAAAAAGGATTTACCACACATTAAAGTTGTG
ATGCTTACAAGTTTCATTGAAGATAAAGAAGTGTATCGAGCTCTAGATGCTGGTGTAGATAGTTATATCTTAAAGACCAC
AAGTGCTAGTGATATCGCAGAAGCGGTTCGTAAAACATATCATGGTGAATCGGTATTTGAACCAGAAGTATTAGTTAAAA
TGCGTAACAGAATGAAAAAACGTGCTGAGCTATACGAAATGTTAACAGATAGAGAAATGGAAATTTTATTGTTAATTGCT
AAAGGTTATTCTAATCAAGAGATTGCTAGTGCATCTCATATTACAATAAAAACAGTAAAAACTCATGTAAGTAATATTCT
AAGTAAATTAGAAGTTCAAGATAGAACACAGGCAGTCATTTATGCATTCCAACATAACTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2T4Q1G3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

93.78

100

0.938
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368