Detailed information NTG0450197

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FOC62_RS05295
• Genome accession: NZ_CP054017
• Coordinates: 1029911..1030954 (-)
• Length: 347 a.a.
• NCBI ID: WP_002452288.1
• Uniprot ID: A0A2T4Q1J8
• Organism: Staphylococcus warneri strain FDAARGOS_754
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1024911..1035954

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FOC62_RS05265 (FOC62_05270)	-	1025411..1026652 (-)	1242	WP_002452294.1	aminopeptidase	-
FOC62_RS05270 (FOC62_05275)	-	1026665..1026868 (-)	204	WP_002452293.1	DUF1128 domain-containing protein	-
FOC62_RS05275 (FOC62_05280)	-	1027015..1027479 (+)	465	WP_002452292.1	low molecular weight protein-tyrosine-phosphatase	-
FOC62_RS05280 (FOC62_05285)	-	1027486..1027770 (+)	285	WP_002452291.1	hypothetical protein	-
FOC62_RS05285 (FOC62_05290)	-	1027999..1029234 (+)	1236	WP_002452290.1	YihY/virulence factor BrkB family protein	-
FOC62_RS05290 (FOC62_05295)	vraR	1029292..1029921 (-)	630	WP_002452289.1	two-component system response regulator VraR	Regulator
FOC62_RS05295 (FOC62_05300)	vraS	1029911..1030954 (-)	1044	WP_002452288.1	sensor histidine kinase	Regulator
FOC62_RS05300 (FOC62_05305)	liaF	1030951..1031652 (-)	702	WP_002452287.1	cell wall-active antibiotics response protein LiaF	-
FOC62_RS05305 (FOC62_05310)	-	1031667..1032053 (-)	387	WP_002452286.1	DUF2543 family protein	-
FOC62_RS05310 (FOC62_05315)	map	1032197..1032952 (-)	756	WP_002452285.1	type I methionyl aminopeptidase	-
FOC62_RS05315 (FOC62_05320)	-	1033116..1034105 (+)	990	WP_002452284.1	aromatic acid exporter family protein	-
FOC62_RS05320 (FOC62_05325)	-	1034160..1034885 (-)	726	WP_002452283.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40101.60 Da
• Isoelectric Point: 6.2449

>NTDB_id=450197 FOC62_RS05295 WP_002452288.1 1029911..1030954(-) (vraS) [Staphylococcus warneri strain FDAARGOS_754]
MNHYIRAIGSMLILIYSMLTAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNIIVILLCIIVGSVLAYKINQQNDWIKT
QIERSIEGETVGINDQNIELYSETLEIYHTLVPLNQELHRLRMKTQNLTNENYNMNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETQLEPPLDQQIPVLEKMIQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QEFKVPKGIEDHLFRITQEAISNTLRHSNGTRVTVELFNKQDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYGD

Nucleotide

• Length: 1044 bp

>NTDB_id=450197 FOC62_RS05295 WP_002452288.1 1029911..1030954(-) (vraS) [Staphylococcus warneri strain FDAARGOS_754]
ATGAATCACTATATAAGAGCCATTGGGTCAATGCTGATATTGATATATAGTATGTTAACGGCATTCTTATTTATTGATAA
AGTTTTTGTTAACATCATTTACTTTCAAGGCATGTTTTATACACAAATTTTCGGTATTCCAGTGTTCTTATTCTTAAATA
TTATAGTTATATTATTATGTATTATAGTCGGATCAGTTCTAGCATATAAAATTAATCAACAGAATGATTGGATTAAAACT
CAAATTGAGCGATCAATTGAAGGGGAAACAGTTGGTATTAATGACCAAAATATTGAATTGTATAGTGAGACTTTAGAAAT
ATATCATACACTCGTTCCATTAAATCAAGAGTTACATCGATTAAGAATGAAAACACAAAATTTAACTAACGAAAATTACA
ATATGAATGATGTTAAAGTTAAAAAAATTATTGAAGACGAGCGACAACGTTTAGCAAGAGAATTACACGATTCTGTAAGT
CAACAACTATTCGCTGCAAGTATGATGTTATCAGCAATTAAAGAAACACAGTTAGAACCACCATTAGATCAACAAATACC
TGTACTCGAAAAAATGATTCAAGATTCTCAACTTGAAATGAGAGCGTTGTTACTTCATTTAAGACCGCTAGGATTAAAAG
ATAAATCATTAGGTGAAGGAATTAAAGATTTAGTCATTGACCTTCAAAAGAAAGTTCCAATGAAAGTAGTACATGAGATT
CAAGAATTTAAAGTACCAAAAGGAATAGAGGATCATTTATTCAGAATTACACAAGAAGCAATTTCAAATACTTTGAGACA
TTCTAATGGTACAAGAGTAACGGTTGAATTATTTAATAAACAAGATTATTTATTGTTACGTATACAAGATAATGGTAAAG
GTTTTAATGTAGACGAGAAACTTGAGCAAAGTTATGGATTAAAGAATATGCGTGAACGTGCACTAGAAATTGGTGCTACT
TTCCATATCGTTTCATTACCAGATTCTGGTACACGTATTGAAGTTAAAGCACCATTAAACAAGGAGGATTCGTATGGCGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A2T4Q1J8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	94.524	100	0.945