Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   FOC68_RS05845 Genome accession   NZ_CP054006
Coordinates   1137649..1138365 (+) Length   238 a.a.
NCBI ID   WP_002448266.1    Uniprot ID   -
Organism   Staphylococcus hominis strain FDAARGOS_762     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1132649..1143365
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC68_RS05820 (FOC68_05825) - 1133374..1133997 (+) 624 WP_002448275.1 nitroreductase family protein -
  FOC68_RS05825 (FOC68_05830) - 1134128..1134913 (+) 786 WP_002448273.1 carbon-nitrogen family hydrolase -
  FOC68_RS05830 (FOC68_05835) - 1135613..1136179 (+) 567 WP_049437391.1 accessory gene regulator AgrB -
  FOC68_RS05835 (FOC68_05840) agrD 1136182..1136322 (+) 141 WP_002448265.1 cyclic lactone autoinducer peptide AgrD -
  FOC68_RS05840 (FOC68_05845) agrC 1136347..1137636 (+) 1290 WP_002448283.1 quorum-sensing sensor histidine kinase AgrC -
  FOC68_RS05845 (FOC68_05850) agrA 1137649..1138365 (+) 717 WP_002448266.1 quorum-sensing response regulator AgrA Regulator
  FOC68_RS05850 (FOC68_05855) - 1138404..1139375 (-) 972 WP_002448269.1 carbohydrate kinase family protein -
  FOC68_RS05855 (FOC68_05860) - 1139376..1140863 (-) 1488 WP_002448284.1 sucrose-6-phosphate hydrolase -
  FOC68_RS11410 - 1140945..1141012 (-) 68 Protein_1100 LacI family DNA-binding transcriptional regulator -
  FOC68_RS05860 (FOC68_05865) - 1141118..1142362 (-) 1245 WP_002448259.1 ammonium transporter -
  FOC68_RS05865 (FOC68_05870) - 1142473..1142697 (-) 225 WP_002448268.1 sulfurtransferase TusA family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27831.68 Da        Isoelectric Point: 5.0583

>NTDB_id=450079 FOC68_RS05845 WP_002448266.1 1137649..1138365(+) (agrA) [Staphylococcus hominis strain FDAARGOS_762]
MKIFICEDDAKQRENMVSIINNYIMIEEKPMEIALATDDPYEIIEQSKEMNDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPNQLKTRIIDCIETAHTRLTLLSKESNVETIELKRGSNSIYVQYDDVM
FFESSTKSHRLIVHLDNRQIEFYGNLKELAQLDDRFFRCHNSFVVNRHNIDSVDSKERIVTFRNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=450079 FOC68_RS05845 WP_002448266.1 1137649..1138365(+) (agrA) [Staphylococcus hominis strain FDAARGOS_762]
ATGAAAATATTCATTTGTGAAGACGATGCGAAACAACGTGAAAATATGGTTTCAATTATTAACAACTATATAATGATTGA
AGAAAAACCGATGGAAATAGCGTTAGCGACAGATGATCCTTATGAAATTATTGAACAGTCAAAAGAAATGAATGATGTTG
GATGTTATTTTTTAGATATACAATTGGAAGCTGATATTAACGGTATTAAACTTGGAAGTGAAATTCGAAAGTATGATCCT
ATTGGGAATATCATCTTTGTTACAAGTCATAGTGAACTCACTTACCTAACATTTGTCTATAAGGTATCTGCAATGGATTT
TATTTTTAAAGATGATCCTAACCAACTTAAAACGAGAATAATAGATTGCATTGAAACTGCTCATACACGTTTAACATTAC
TTTCAAAAGAAAGTAATGTTGAAACAATTGAATTAAAGCGTGGTAGCAATTCAATATATGTACAATATGATGATGTCATG
TTCTTTGAATCGTCTACAAAATCCCATCGTTTAATTGTGCATCTTGATAACCGTCAGATTGAATTCTACGGAAATCTTAA
AGAATTAGCGCAACTCGATGATCGTTTTTTCAGATGTCACAATAGTTTTGTTGTAAATCGTCATAATATCGATTCAGTCG
ATTCTAAAGAACGAATTGTAACTTTCAGAAATGGTGAGCATTGCTATGCCTCTGTACGTAATGTTAAAAAGATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.975

100

0.87
  comE/comE2 Streptococcus gordonii strain NCTC7865

34.263

100

0.361
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

34.263

100

0.361