Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   FOC71_RS04395 Genome accession   NZ_CP053999
Coordinates   841893..842948 (+) Length   351 a.a.
NCBI ID   WP_003073620.1    Uniprot ID   A0AAD1FJ17
Organism   Streptococcus intermedius strain FDAARGOS_769     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 836893..847948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC71_RS04365 (FOC71_04365) - 837411..838046 (-) 636 WP_003073631.1 YigZ family protein -
  FOC71_RS04370 (FOC71_04370) comFA/cflA 838103..839404 (+) 1302 WP_003073629.1 DEAD/DEAH box helicase Machinery gene
  FOC71_RS04375 (FOC71_04375) - 839401..840066 (+) 666 WP_003073628.1 ComF family protein -
  FOC71_RS04380 (FOC71_04380) raiA 840145..840687 (+) 543 WP_003073626.1 ribosome-associated translation inhibitor RaiA -
  FOC71_RS04385 (FOC71_04385) rsmD 840886..841425 (+) 540 WP_003073624.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  FOC71_RS04390 (FOC71_04390) coaD 841415..841912 (+) 498 WP_003073622.1 pantetheine-phosphate adenylyltransferase -
  FOC71_RS04395 (FOC71_04395) sepM 841893..842948 (+) 1056 WP_003073620.1 SepM family pheromone-processing serine protease Regulator
  FOC71_RS04400 (FOC71_04400) - 843230..843793 (+) 564 WP_003073618.1 YutD family protein -
  FOC71_RS04405 (FOC71_04405) rlmN 843827..844909 (+) 1083 WP_003073615.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  FOC71_RS04410 (FOC71_04410) - 844902..845420 (+) 519 WP_003073612.1 VanZ family protein -
  FOC71_RS04415 (FOC71_04415) cclA/cilC 845406..846089 (-) 684 WP_003073610.1 A24 family peptidase Machinery gene
  FOC71_RS04420 (FOC71_04420) - 846240..846767 (+) 528 WP_003073607.1 Dps family protein -
  FOC71_RS04425 (FOC71_04425) - 847029..847253 (+) 225 WP_003073604.1 YqgQ family protein -
  FOC71_RS04430 (FOC71_04430) - 847247..847627 (+) 381 WP_003073602.1 rhodanese-like domain-containing protein -

Sequence

Protein


Download         Length: 351 a.a.        Molecular weight: 38477.49 Da        Isoelectric Point: 10.2603

>NTDB_id=450010 FOC71_RS04395 WP_003073620.1 841893..842948(+) (sepM) [Streptococcus intermedius strain FDAARGOS_769]
MKKTRNKFKKWPIVFVVGLVLLFISFVVPLPYYIEVPGSAADVRQVLRVDNKEDKEKGSYNFVTVGIQHATFAHLVYAWL
TPFTDIYSAKDLTGGTSDKEYMRINQFYMETSQNLAKYQGLKKAGKDISLKYLGVYVLQVTKNSTFKGILNIADTVTGVN
DKTFSSSKDLIDYVGSQKIGSKVKVNYVEDGQKKSAIGKIIKLENGKNGIGISLIDRTEVTSSIPIEFSTAGIGGPSAGL
MFSLAIYTQIAEPTLRDGRNIAGTGSIDREGKVGDIGGIDKKVVSAAKNGAEIFFAPNNPVTKEAKKANSKAKTNYETAL
EAAKKIKTKMKIVPVKNLQDAIDYLKRTKKS

Nucleotide


Download         Length: 1056 bp        

>NTDB_id=450010 FOC71_RS04395 WP_003073620.1 841893..842948(+) (sepM) [Streptococcus intermedius strain FDAARGOS_769]
ATGAAAAAAACAAGAAATAAATTTAAAAAATGGCCGATAGTATTTGTGGTAGGGTTGGTCCTTCTTTTTATCTCTTTTGT
AGTTCCTCTGCCTTATTATATTGAAGTACCAGGTAGTGCAGCAGACGTCCGTCAGGTTTTGCGTGTGGATAACAAAGAAG
ATAAGGAAAAAGGTTCTTACAATTTTGTGACAGTTGGGATTCAGCATGCTACCTTTGCTCATTTAGTTTATGCTTGGCTG
ACCCCTTTTACAGATATTTATTCAGCGAAAGATTTGACTGGCGGAACTTCCGATAAAGAATATATGCGAATCAATCAATT
TTATATGGAAACATCACAAAACTTAGCCAAATATCAAGGGTTAAAAAAAGCAGGAAAGGATATCAGCCTGAAATATTTGG
GCGTCTATGTGTTACAAGTTACCAAAAACTCAACCTTTAAGGGCATTTTAAATATTGCAGATACTGTGACAGGTGTGAAT
GATAAGACTTTTAGTAGTTCAAAAGACTTGATTGATTATGTAGGTTCACAGAAGATTGGTAGTAAGGTAAAAGTAAATTA
TGTTGAAGATGGTCAGAAAAAATCTGCTATAGGTAAAATCATCAAACTTGAAAATGGGAAAAATGGAATTGGTATTAGCT
TGATTGACCGGACAGAGGTTACGAGTAGTATACCGATTGAATTCTCAACTGCGGGAATTGGCGGACCAAGTGCGGGCTTG
ATGTTTAGTTTGGCAATTTATACACAGATTGCTGAACCAACATTAAGAGACGGTAGAAATATTGCTGGTACGGGCTCAAT
TGACCGTGAAGGAAAAGTTGGCGATATTGGAGGTATTGATAAAAAGGTGGTCTCAGCAGCCAAAAATGGTGCAGAAATTT
TCTTTGCACCAAATAATCCAGTCACCAAAGAAGCTAAAAAAGCCAATTCTAAAGCGAAAACAAATTATGAAACAGCTTTG
GAAGCTGCTAAAAAAATTAAAACCAAAATGAAAATTGTACCTGTCAAGAACTTGCAAGATGCTATTGATTACCTCAAACG
TACCAAGAAATCTTAA

Domains

Predicted by InterproScan.

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(234-300)

PDZ domain (PDZ_2)

(133-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

63.478

98.291

0.624