Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   FOC73_RS00235 Genome accession   NZ_CP053998
Coordinates   50129..51469 (+) Length   446 a.a.
NCBI ID   WP_002885062.1    Uniprot ID   A0A0F3HCD0
Organism   Streptococcus salivarius strain FDAARGOS_771     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 45129..56469
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOC73_RS00205 (FOC73_00205) - 45200..45967 (-) 768 WP_002884172.1 amino acid ABC transporter ATP-binding protein -
  FOC73_RS00210 (FOC73_00210) - 46155..46805 (-) 651 WP_002886253.1 amino acid ABC transporter permease -
  FOC73_RS00215 (FOC73_00215) - 46817..47515 (-) 699 WP_002886251.1 amino acid ABC transporter permease -
  FOC73_RS00220 (FOC73_00220) - 47533..48366 (-) 834 WP_172855705.1 transporter substrate-binding domain-containing protein -
  FOC73_RS00225 (FOC73_00225) - 48376..49143 (-) 768 WP_002885036.1 amino acid ABC transporter ATP-binding protein -
  FOC73_RS00230 (FOC73_00230) vicR 49429..50136 (+) 708 WP_002884978.1 response regulator YycF Regulator
  FOC73_RS00235 (FOC73_00235) vicK 50129..51469 (+) 1341 WP_002885062.1 cell wall metabolism sensor histidine kinase VicK Regulator
  FOC73_RS00240 (FOC73_00240) vicX 51475..52287 (+) 813 WP_002885031.1 MBL fold metallo-hydrolase Regulator
  FOC73_RS00245 (FOC73_00245) - 52346..52705 (+) 360 WP_002885010.1 YbaN family protein -
  FOC73_RS00250 (FOC73_00250) - 52757..53971 (-) 1215 WP_002885109.1 aminoacyltransferase -
  FOC73_RS00255 (FOC73_00255) yidA 53973..54782 (-) 810 WP_002885000.1 sugar-phosphatase -
  FOC73_RS00260 (FOC73_00260) - 54960..55826 (+) 867 WP_002885116.1 GNAT family N-acetyltransferase -
  FOC73_RS00265 (FOC73_00265) - 55908..56294 (+) 387 WP_002884910.1 DUF1934 domain-containing protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50945.21 Da        Isoelectric Point: 5.1606

>NTDB_id=449914 FOC73_RS00235 WP_002885062.1 50129..51469(+) (vicK) [Streptococcus salivarius strain FDAARGOS_771]
MTSIGLNITSFELALLFTLLFVAFYFIFLAYRDYRRVKNIRKLTKRVKSLMAGNYNEELRLKGDPELLELADSLNDLSDV
FRLTHENLAQEKNRLSSVLSYMSDGVIATNRRGQITMINSTAQRLLNLDYETATQMSILDLLDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALDE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLDVEMTNFTAFMTYILNRFDQIKSQETNTGKTYEIIRDYPVNSI
WVEIDTDKMTQVVDNILNNAIKYSPDGGKITVSMKTTDSQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=449914 FOC73_RS00235 WP_002885062.1 50129..51469(+) (vicK) [Streptococcus salivarius strain FDAARGOS_771]
ATGACTAGTATTGGCTTAAACATCACAAGCTTTGAACTAGCCTTACTCTTTACGCTCCTCTTTGTGGCTTTCTACTTTAT
TTTTCTGGCTTATCGTGATTATCGACGAGTCAAAAATATTCGAAAGTTGACCAAGAGGGTCAAGTCCTTAATGGCAGGTA
ACTATAACGAGGAGTTACGCTTAAAGGGTGATCCAGAGCTTTTAGAGCTAGCTGACAGCTTGAATGATTTATCGGATGTC
TTTCGTTTGACGCATGAAAATCTAGCCCAGGAAAAAAACCGCTTATCATCAGTCCTTTCTTACATGAGTGATGGGGTTAT
TGCGACAAATCGTCGTGGTCAAATTACCATGATTAATAGCACAGCTCAGCGTTTGTTGAATCTAGATTATGAAACAGCGA
CACAGATGTCCATTTTAGATTTATTAGATGGCGAAAATCCCTATACTTATAGTGAATTGCTGTCTAAGACTCCTGAAATT
CATTTGTCACGTCGAGATGCCAACGATGAGTTTGTGACCTTACGTGTTAATTTTGCCCTTATTCGTAAAGAATCAGGTTT
TATCTCAGGTCTGGTTGCCGTTCTTCACGATGCCACTGAGCAGGAAAAAGAAGAGCGTGAACGTCGACTCTTCGTCTCAA
ACGTTAGTCATGAGTTGCGTACACCTTTGACTTCTGTAAAATCCTATCTGGAGGCACTTGATGATGGTGCTCTCGACGAA
GAGATTGCTCCTAACTTTATCAAAGTTTCTTTGGATGAGACCAATCGTATGATGCGAATGATTTCTGACCTCTTGGCACT
ATCACGTATTGACAATAAGAGTACCCAACTTGACGTTGAGATGACCAATTTCACGGCCTTCATGACCTATATCTTGAATC
GTTTTGATCAGATTAAAAGTCAAGAAACCAATACAGGTAAAACTTACGAAATCATTCGCGATTATCCGGTAAACTCAATT
TGGGTGGAGATTGATACAGATAAGATGACCCAGGTTGTGGATAATATTCTTAATAATGCTATCAAGTATTCGCCTGATGG
TGGTAAGATTACAGTGTCTATGAAGACAACTGATTCACAGTTGATTGTTTCTATTTCTGACCAAGGTTTGGGTATTCCTA
AGAAAGATTTGCCGTTGATTTTCGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCCCAAGGTGGAACTGGTCTA
GGCTTGTCTATTGCAAAAGAAATTATTAAACAACATAAGGGCTTTATTTGGGCTAAGAGTGAGTATGGTAAGGGTTCAAC
TTTTACAATTGTGCTTCCATATGACAAGGATGCCATGATGGTTGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0F3HCD0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92.825

0.684
  micB Streptococcus pneumoniae Cp1015

67.667

97.085

0.657