Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   ST4067_RS08755 Genome accession   NZ_CP065496
Coordinates   1682867..1683160 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus strain 4067     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1677867..1688160
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4067_RS08720 (ST4067_08735) - 1678270..1678713 (-) 444 WP_011681680.1 hypothetical protein -
  ST4067_RS08725 - 1678787..1679212 (-) 426 WP_263604536.1 CPBP family intramembrane glutamic endopeptidase -
  ST4067_RS08730 (ST4067_08745) - 1679455..1679652 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  ST4067_RS08735 (ST4067_08750) - 1679901..1681094 (-) 1194 WP_014608740.1 acetate kinase -
  ST4067_RS08740 (ST4067_08755) comGH 1681150..1682106 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  ST4067_RS08745 (ST4067_08760) comGG 1682151..1682468 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  ST4067_RS08750 (ST4067_08765) comGF 1682446..1682883 (-) 438 WP_263604537.1 competence type IV pilus minor pilin ComGF Machinery gene
  ST4067_RS08755 (ST4067_08770) comGE 1682867..1683160 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  ST4067_RS08760 (ST4067_08775) comGD 1683132..1683560 (-) 429 WP_263604538.1 competence type IV pilus minor pilin ComGD Machinery gene
  ST4067_RS08765 (ST4067_08780) comGC 1683520..1683846 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  ST4067_RS08770 (ST4067_08785) comGB 1683843..1684943 (-) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  ST4067_RS08775 (ST4067_08790) comGA/cglA/cilD 1684825..1685766 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  ST4067_RS08780 (ST4067_08795) - 1685847..1686209 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=449298 ST4067_RS08755 WP_011226625.1 1682867..1683160(-) (comGE) [Streptococcus thermophilus strain 4067]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=449298 ST4067_RS08755 WP_011226625.1 1682867..1683160(-) (comGE) [Streptococcus thermophilus strain 4067]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361