Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   ST4145_RS00345 Genome accession   NZ_CP065492
Coordinates   60720..61310 (+) Length   196 a.a.
NCBI ID   WP_011680603.1    Uniprot ID   Q03MX8
Organism   Streptococcus thermophilus strain 4145     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 55720..66310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ST4145_RS00320 (ST4145_00320) - 56850..57305 (-) 456 Protein_42 DUF3021 domain-containing protein -
  ST4145_RS00325 (ST4145_00325) - 57302..57693 (-) 392 Protein_43 LytTR family DNA-binding domain-containing protein -
  ST4145_RS00330 (ST4145_00330) - 57917..58222 (+) 306 WP_014621013.1 hypothetical protein -
  ST4145_RS00335 (ST4145_00335) hexB 58274..60217 (+) 1944 WP_024009694.1 DNA mismatch repair endonuclease MutL Machinery gene
  ST4145_RS00340 (ST4145_00340) - 60347..60568 (+) 222 WP_011680602.1 hypothetical protein -
  ST4145_RS00345 (ST4145_00345) ruvA 60720..61310 (+) 591 WP_011680603.1 Holliday junction branch migration protein RuvA Machinery gene
  ST4145_RS00350 (ST4145_00350) - 61317..61871 (+) 555 WP_024009695.1 DNA-3-methyladenine glycosylase I -
  ST4145_RS00355 (ST4145_00355) cinA 61967..63238 (+) 1272 WP_011680605.1 competence/damage-inducible protein A Machinery gene
  ST4145_RS00360 (ST4145_00360) recA 63274..64413 (+) 1140 WP_011680606.1 recombinase RecA Machinery gene
  ST4145_RS00365 (ST4145_00365) spx 64590..64988 (+) 399 WP_002949058.1 transcriptional regulator Spx -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21683.98 Da        Isoelectric Point: 5.2834

>NTDB_id=448895 ST4145_RS00345 WP_011680603.1 60720..61310(+) (ruvA) [Streptococcus thermophilus strain 4145]
MYDYIKGTLVKITAKHIVIETNGLGYIVTVANPYSFSDQMNQTIQVYLHQVIRDDAHLLFGFHTEDEKEVFLKLISVSGI
GPTTALAIVAVDDNQGLVAAIDNSDIKYLMKFPKIGKKTAQQMVLDLAGKFAELPAETTNTTANQTAGNQQLDEAMEALL
ALGYKATELKKVKAFFEDTNETAEQYIKSALKMLMK

Nucleotide


Download         Length: 591 bp        

>NTDB_id=448895 ST4145_RS00345 WP_011680603.1 60720..61310(+) (ruvA) [Streptococcus thermophilus strain 4145]
ATGTATGATTATATCAAGGGCACCCTAGTAAAAATCACAGCCAAACACATTGTCATAGAAACAAATGGTCTAGGATATAT
TGTCACTGTGGCTAATCCCTACAGCTTTTCTGATCAAATGAATCAGACTATCCAAGTGTATCTTCATCAAGTTATTAGAG
ATGATGCCCACCTACTTTTTGGTTTTCATACTGAAGATGAGAAAGAAGTTTTTCTTAAGTTGATTTCTGTTTCTGGGATA
GGTCCGACGACTGCTCTAGCCATAGTGGCTGTGGATGATAATCAGGGACTTGTTGCTGCTATTGATAATAGTGACATCAA
ATACCTGATGAAATTTCCAAAGATTGGTAAAAAGACTGCTCAACAAATGGTTCTTGATCTGGCAGGAAAATTTGCAGAGT
TACCAGCAGAAACGACCAATACTACGGCAAATCAGACTGCAGGAAATCAACAGTTGGATGAAGCTATGGAAGCTTTGCTT
GCTCTTGGGTACAAAGCCACAGAGCTTAAGAAAGTGAAAGCCTTCTTTGAGGATACCAATGAAACGGCAGAGCAATATAT
TAAGTCCGCTCTTAAAATGTTGATGAAGTGA

Domains

Predicted by InterProScan.

RuvA, C-terminal domain (RuvA_C)

(151-195)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA N terminal domain (RuvA_N)

(1-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03MX8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.5

100

0.679
  ruvA Streptococcus pneumoniae R6

66.5

100

0.679
  ruvA Streptococcus pneumoniae D39

66.5

100

0.679
  ruvA Bacillus subtilis subsp. subtilis str. 168

42.647

100

0.444