Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GE022_RS04480 Genome accession   NZ_CP053790
Coordinates   911954..913264 (+) Length   436 a.a.
NCBI ID   WP_164228038.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_77_2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 906954..918264
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE022_RS04465 (GE022_004455) phoU 907689..908342 (+) 654 WP_164405320.1 phosphate signaling complex protein PhoU -
  GE022_RS04470 (GE022_004460) - 908547..911084 (+) 2538 WP_164405321.1 M1 family metallopeptidase -
  GE022_RS04475 (GE022_004465) ciaR 911287..911961 (+) 675 WP_003048303.1 response regulator transcription factor Regulator
  GE022_RS04480 (GE022_004470) ciaH 911954..913264 (+) 1311 WP_164228038.1 sensor histidine kinase Regulator
  GE022_RS04485 (GE022_004475) rpsT 913709..913957 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  GE022_RS04490 (GE022_004480) coaA 914011..914931 (-) 921 WP_164228037.1 type I pantothenate kinase -
  GE022_RS04495 (GE022_004485) - 915199..915798 (+) 600 WP_307761754.1 class I SAM-dependent methyltransferase -
  GE022_RS04500 (GE022_004490) - 915785..917062 (+) 1278 WP_164405322.1 pyrimidine-nucleoside phosphorylase -
  GE022_RS04505 (GE022_004495) deoC 917078..917740 (+) 663 WP_003048312.1 deoxyribose-phosphate aldolase -
  GE022_RS04510 (GE022_004500) - 917727..918116 (+) 390 WP_003048314.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49762.34 Da        Isoelectric Point: 9.4415

>NTDB_id=447212 GE022_RS04480 WP_164228038.1 911954..913264(+) (ciaH) [Streptococcus canis strain HL_77_2]
MSKLKKEILSDQYTHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNII
KALPDSDSSKLLGSPAANTDIILFSANGTILNSFNAFSNYQNFHLDERRLGTIVTTSLVNFYGQEEKYHTITVRVHIKNY
PAVAYMMAIVNVDQLDSANERYEQIIIIVMVIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDAQFFDTIFKNYQLVVEESGKVFRSDN
QVNRILKMDKALLKQLMTILVDNAIKYTDKNGVVEIKVKTTDKTLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVTSLKGSITVKDNFPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=447212 GE022_RS04480 WP_164228038.1 911954..913264(+) (ciaH) [Streptococcus canis strain HL_77_2]
ATGAGTAAATTAAAAAAAGAGATTCTGTCAGATCAGTACACTCACTTTTTCCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTCATTATGACCATTATTATTTTACAGATTATGAGGTTTGGGGTTTATTCGTCTGTTGATAGTAGCCTGATTTCTGTTA
GTAATAATGCTAGTAGCTATGCCAATCGAACCATGGCTAGAATATCTTCCTTCTACTTTGATGCTGAAAATAATATTATT
AAGGCGCTACCTGACTCTGATAGTTCAAAATTACTAGGATCCCCTGCAGCTAATACAGATATTATTTTGTTCAGTGCTAA
TGGGACGATTTTAAATTCCTTCAATGCCTTCTCCAATTACCAAAATTTTCATCTGGACGAACGACGGTTAGGAACTATTG
TGACAACTAGTCTCGTGAATTTTTATGGTCAAGAAGAAAAGTACCATACGATAACTGTTAGGGTTCATATCAAAAATTAC
CCTGCTGTCGCTTATATGATGGCTATTGTCAATGTGGATCAATTGGATAGTGCTAATGAACGCTATGAGCAAATCATCAT
CATTGTGATGGTTATCTTTTGGCTGATTTCCATTTTAGCTAGTATTTATTTATCTAAGTGGAGTCGAAAACCGATTTTGG
AAAGTTATGAAAAGCAAAAGATGTTTGTGGAAAATGCCAGCCATGAATTAAGAACCCCTCTAGCTGTTTTACAAAACCGC
TTGGAATCCCTCTTTCGAAAACCTAACGAAACTATTTTGGAAAATAGTGAGCACCTTGCCTCTAGTTTGGACGAAGTCCG
AAACATGCGTATTCTAACGACCAATCTATTGAATTTGGCCAGGCGAGATGACGGTATCAATCCGCAATGGACAGATTTGG
ATGCTCAATTCTTTGATACCATTTTTAAGAACTATCAATTAGTTGTTGAAGAATCTGGCAAAGTCTTTCGCTCCGATAAT
CAAGTCAATCGCATCTTGAAAATGGACAAGGCATTATTAAAACAACTCATGACGATTTTAGTCGATAATGCCATCAAATA
CACCGATAAAAATGGAGTAGTTGAGATAAAGGTCAAAACAACCGATAAAACCTTGCTCATTTCGGTTATTGATAATGGGC
CAGGGATAAAAGACGAAGAGAAGAAAAAGATTTTTGATCGATTCTATCGGGTTGATAAAGCTAGAACACGCCAGACAGGT
GGCTTTGGCTTAGGATTAGCATTAGCCCAACAGATTGTGACGTCATTAAAAGGAAGTATCACAGTAAAAGATAACTTCCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

50.913

100

0.511
  ciaH Streptococcus pneumoniae D39

50.913

100

0.511
  ciaH Streptococcus pneumoniae R6

50.913

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

50.913

100

0.511