Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   GE023_RS04295 Genome accession   NZ_CP053789
Coordinates   872688..873998 (+) Length   436 a.a.
NCBI ID   WP_159305891.1    Uniprot ID   -
Organism   Streptococcus canis strain HL_98_2     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 867688..878998
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GE023_RS04280 (GE023_004275) phoU 868422..869075 (+) 654 WP_003048299.1 phosphate signaling complex protein PhoU -
  GE023_RS04285 (GE023_004280) - 869281..871818 (+) 2538 WP_159305890.1 M1 family metallopeptidase -
  GE023_RS04290 (GE023_004285) ciaR 872021..872695 (+) 675 WP_003048303.1 response regulator transcription factor Regulator
  GE023_RS04295 (GE023_004290) ciaH 872688..873998 (+) 1311 WP_159305891.1 cell wall metabolism sensor histidine kinase WalK Regulator
  GE023_RS04300 (GE023_004295) rpsT 874444..874692 (-) 249 WP_009881183.1 30S ribosomal protein S20 -
  GE023_RS04305 (GE023_004300) coaA 874746..875666 (-) 921 WP_159304996.1 type I pantothenate kinase -
  GE023_RS04310 (GE023_004305) - 875934..876533 (+) 600 WP_003048308.1 class I SAM-dependent methyltransferase -
  GE023_RS04315 (GE023_004310) - 876520..877797 (+) 1278 WP_159304997.1 pyrimidine-nucleoside phosphorylase -
  GE023_RS04320 (GE023_004315) deoC 877813..878475 (+) 663 WP_003048312.1 deoxyribose-phosphate aldolase -
  GE023_RS04325 (GE023_004320) - 878462..878851 (+) 390 WP_159304998.1 cytidine deaminase -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49748.27 Da        Isoelectric Point: 9.3067

>NTDB_id=447157 GE023_RS04295 WP_159305891.1 872688..873998(+) (ciaH) [Streptococcus canis strain HL_98_2]
MSKLKKEILSDQYTHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLISVSNNASSYANRTMARISSFYFDAENNII
KALPDSDSSKLLGSPAANTDIILFSANGTILNSFNAFSNYQNFHLDERRLGTIVTTSLVNFYGQEEKYHTITVRVHIKNY
PAVAYMMAIVNVDQLDSANERYEQIIIIVMVIFWLISILASIYLSKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTDLDAQFFDTIFKNYQLVVEESGKVFRSDN
QVNRILKMDKALLKQLMTILVDNAIKYTDKNGVVEINVKTTDKTLLISVIDNGPGIKDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVTSLKGSITVKDNFPKGSIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=447157 GE023_RS04295 WP_159305891.1 872688..873998(+) (ciaH) [Streptococcus canis strain HL_98_2]
ATGAGTAAATTAAAAAAAGAGATTCTGTCAGATCAGTACACTCACTTTTTCCATTTTTTTGCGGTCTTTACAGGTATTTT
TGTCATTATGACCATTATTATTTTACAGATTATGAGGTTTGGGGTTTATTCGTCTGTTGATAGTAGCCTGATTTCTGTTA
GTAATAATGCTAGTAGTTATGCCAATCGAACCATGGCTAGAATATCCTCCTTCTACTTTGATGCTGAAAATAATATTATT
AAGGCGCTACCTGACTCTGATAGTTCAAAATTACTAGGCTCCCCTGCAGCTAATACAGATATTATTTTGTTCAGTGCTAA
TGGGACGATTTTAAATTCCTTCAATGCCTTCTCCAATTACCAAAATTTTCATCTGGACGAACGACGGTTAGGAACTATTG
TGACAACTAGTCTCGTGAATTTTTATGGTCAAGAAGAAAAGTACCATACGATAACTGTTAGGGTTCATATCAAAAATTAC
CCTGCTGTCGCTTATATGATGGCTATTGTCAATGTGGATCAATTGGATAGCGCTAATGAACGCTATGAGCAAATCATCAT
CATTGTGATGGTTATCTTTTGGCTGATTTCCATTTTAGCTAGTATTTATTTATCTAAGTGGAGTCGAAAACCGATTTTGG
AAAGTTATGAAAAGCAAAAGATGTTTGTGGAAAATGCCAGCCATGAATTAAGAACCCCTCTAGCTGTTTTACAAAACCGC
TTGGAATCCCTCTTTCGAAAACCTAACGAAACTATTTTGGAAAATAGTGAGCACCTTGCCTCTAGTTTGGACGAAGTCCG
AAACATGCGTATTCTAACGACCAATCTATTGAATTTGGCCAGGCGAGATGACGGTATCAATCCGCAATGGACAGATTTGG
ATGCTCAATTCTTTGATACCATTTTTAAGAACTATCAATTAGTTGTTGAAGAATCTGGCAAAGTCTTTCGCTCCGATAAT
CAAGTCAATCGTATCTTGAAAATGGACAAGGCATTATTAAAACAACTCATGACGATTTTAGTCGATAATGCCATCAAATA
CACCGATAAAAATGGAGTAGTTGAGATAAATGTCAAAACAACCGATAAAACCTTGCTCATTTCGGTTATTGATAATGGGC
CAGGGATAAAAGACGAAGAGAAGAAAAAGATTTTTGATCGATTCTATCGGGTTGATAAAGCTAGAACACGCCAGACAGGT
GGCTTTGGCTTAGGATTAGCATTAGCCCAACAGATTGTGACGTCATTAAAAGGAAGTATCACAGTAAAAGATAACTTCCC
TAAAGGTAGTATTTTTGAAGTCAAATTATAA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

50.913

100

0.511
  ciaH Streptococcus pneumoniae D39

50.913

100

0.511
  ciaH Streptococcus pneumoniae R6

50.913

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

50.913

100

0.511