Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   C270_RS06905 Genome accession   NC_018673
Coordinates   1408992..1409948 (-) Length   318 a.a.
NCBI ID   WP_014974863.1    Uniprot ID   K0DBK9
Organism   Leuconostoc carnosum JB16     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1403992..1414948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C270_RS06865 (C270_06680) - 1404017..1405273 (-) 1257 WP_014974855.1 acetate kinase -
  C270_RS06870 (C270_06685) - 1405400..1406413 (-) 1014 WP_014974856.1 class I SAM-dependent methyltransferase -
  C270_RS06875 (C270_06690) - 1406445..1406741 (-) 297 WP_014974857.1 hypothetical protein -
  C270_RS06880 (C270_06695) - 1406742..1407158 (-) 417 WP_014974858.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  C270_RS09030 (C270_06700) - 1407142..1407354 (-) 213 WP_014974859.1 hypothetical protein -
  C270_RS06890 (C270_06705) - 1407329..1407721 (-) 393 WP_014974860.1 prepilin-type N-terminal cleavage/methylation domain-containing protein -
  C270_RS06895 (C270_06710) comGC 1407705..1408016 (-) 312 WP_014974861.1 competence type IV pilus major pilin ComGC Machinery gene
  C270_RS06900 (C270_06715) - 1408013..1409050 (-) 1038 WP_014974862.1 type II secretion system F family protein -
  C270_RS06905 (C270_06720) comGA 1408992..1409948 (-) 957 WP_014974863.1 competence type IV pilus ATPase ComGA Machinery gene
  C270_RS06910 (C270_06725) - 1410046..1411398 (-) 1353 WP_014974864.1 glucose-6-phosphate isomerase -
  C270_RS06915 (C270_06730) nagB 1411522..1412223 (-) 702 WP_014974865.1 glucosamine-6-phosphate deaminase -
  C270_RS06920 (C270_06735) - 1412352..1413629 (-) 1278 WP_014974866.1 serine hydrolase -
  C270_RS06925 (C270_06740) - 1413616..1414722 (-) 1107 WP_014974867.1 HAMP domain-containing sensor histidine kinase -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 36314.85 Da        Isoelectric Point: 6.3075

>NTDB_id=44684 C270_RS06905 WP_014974863.1 1408992..1409948(-) (comGA) [Leuconostoc carnosum JB16]
MNDILEAAIEQKVNDIYLLPTEDQQYVIKFHLDGQAVTFKQISEINAQTMISALKYRAKMNISERRRPQLGRFQNDEIWL
RVSTVGDFLNRETVVLRLIYPQRQTQNWLVSQQFEAIQTALPSAGLFLISGPTGSGKTTTLYRLLDQLADDKLVLTIEDP
VEIQQPKFVQLQVNEDAGIYYDELIKVALRHRPEILLVGEIRDKKTAQAAVQAALSGHLVLSTVHAMSARDVIVRLQDLG
VDHMKLMAALAGVVYQRLLPTNNHQQAAIMDMLNDHLLERVMRGDEIPKFSKKWQEVLQHAMDQQIISQETCETYQKL

Nucleotide


Download         Length: 957 bp        

>NTDB_id=44684 C270_RS06905 WP_014974863.1 1408992..1409948(-) (comGA) [Leuconostoc carnosum JB16]
ATGAATGATATTTTAGAGGCAGCTATTGAACAAAAAGTAAATGATATTTATCTTTTACCCACCGAGGATCAACAATATGT
GATTAAGTTTCATCTTGATGGTCAAGCAGTGACATTTAAACAAATATCTGAAATAAATGCGCAAACAATGATTTCAGCGC
TTAAATATCGTGCCAAAATGAATATTTCAGAACGCAGGCGACCACAATTAGGTCGTTTTCAAAATGATGAGATTTGGCTA
CGTGTATCTACTGTTGGTGATTTTTTGAACCGAGAAACAGTTGTTTTGCGACTTATTTATCCGCAAAGGCAGACACAAAA
TTGGCTCGTTTCTCAACAGTTTGAAGCAATACAGACAGCATTGCCGAGTGCAGGTCTATTTTTAATTTCTGGGCCAACAG
GGTCCGGGAAAACAACAACTCTTTATCGTCTATTAGACCAATTAGCAGATGATAAACTCGTATTGACAATTGAAGATCCA
GTTGAAATTCAACAACCAAAATTTGTGCAATTACAAGTTAATGAAGATGCTGGTATTTATTATGATGAGTTAATCAAAGT
AGCACTACGACATCGACCAGAAATCTTATTAGTAGGTGAAATTCGTGATAAGAAAACGGCGCAGGCAGCCGTTCAAGCCG
CACTAAGTGGGCATTTGGTATTAAGTACTGTGCATGCTATGTCAGCACGTGATGTTATTGTACGGTTACAGGATCTAGGC
GTCGATCATATGAAACTAATGGCGGCATTGGCTGGTGTTGTTTATCAACGTTTATTGCCAACTAACAACCATCAACAAGC
AGCCATCATGGATATGCTCAATGATCATCTACTTGAACGTGTTATGCGTGGTGATGAGATTCCTAAATTTTCAAAAAAAT
GGCAGGAGGTGTTACAACATGCAATGGATCAGCAAATTATTTCGCAAGAAACATGTGAAACCTATCAAAAGCTTTAG

Domains

Predicted by InterProScan.

Type II/IV secretion system protein (T2SSE)

(4-260)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0DBK9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Latilactobacillus sakei subsp. sakei 23K

44.28

85.22

0.377
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

41.053

89.623

0.368
  comGA Streptococcus mutans UA140

38.796

94.025

0.365
  comGA Streptococcus mutans UA159

38.796

94.025

0.365

Multiple sequence alignment