Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPELS_RS00215 Genome accession   NC_017063
Coordinates   37825..38568 (+) Length   247 a.a.
NCBI ID   WP_001208413.1    Uniprot ID   -
Organism   Helicobacter pylori ELS37     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 32825..43568
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPELS_RS00190 (HPELS_00160) panD 34987..35337 (+) 351 WP_000142295.1 aspartate 1-decarboxylase -
  HPELS_RS00195 (HPELS_00165) - 35348..35641 (+) 294 WP_000347919.1 YbaB/EbfC family nucleoid-associated protein -
  HPELS_RS00200 (HPELS_00170) - 35641..36636 (+) 996 WP_000468496.1 PDZ domain-containing protein -
  HPELS_RS00205 (HPELS_00175) comB6 36644..37699 (+) 1056 WP_000786648.1 P-type conjugative transfer protein TrbL Machinery gene
  HPELS_RS00210 (HPELS_00180) comB7 37715..37828 (+) 114 WP_001217873.1 hypothetical protein Machinery gene
  HPELS_RS00215 (HPELS_00185) comB8 37825..38568 (+) 744 WP_001208413.1 type IV secretion system protein Machinery gene
  HPELS_RS00220 (HPELS_00190) comB9 38568..39542 (+) 975 WP_014419477.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPELS_RS00225 (HPELS_00195) comB10 39535..40665 (+) 1131 WP_001045890.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPELS_RS00230 (HPELS_00200) - 40736..42148 (+) 1413 WP_000694959.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPELS_RS00235 (HPELS_00205) gmd 42189..43334 (+) 1146 WP_000659804.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28722.91 Da        Isoelectric Point: 8.9954

>NTDB_id=44664 HPELS_RS00215 WP_001208413.1 37825..38568(+) (comB8) [Helicobacter pylori ELS37]
MREKPFNSEQLVFLEELLSHQERHLENKLSGFSVNDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISLLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLTNENKLVYEKRYKIVLSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=44664 HPELS_RS00215 WP_001208413.1 37825..38568(+) (comB8) [Helicobacter pylori ELS37]
ATGAGAGAAAAGCCTTTCAACAGCGAGCAATTAGTCTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAGGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAATGATTTGGACATGCAAAGCGTGTTCAGACTGGAGAGAAACCGCTTGAAAATCGCTT
ACAAGCTCTTAGGCTTGATGAGTTTTATCGCTCTTATCTTAGCGATCGTGTTAATCAGTCTTCTACCCTTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCTAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACCGAGAGAGCATTAACCGCATTGACGATAAATCGCGCT
ATGAACTGGTGCGCTTGCAAAGCAGTTCTAAGGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATCTAT
GCACAAAGCCATTTAGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCCATTGCGGCTAAACTAACGAATGAAAACAAGCTTGTGTATGAAAAGCGTTATAAGATCGTATTGAGTTATCTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCTAAAAACCCTACCGGCTTTAAAATCACTCGCTACAGCATCACTGAAATC
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.571

100

0.976

Multiple sequence alignment