Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   IPT86_RS19735 Genome accession   NZ_CP064847
Coordinates   4095628..4096287 (+) Length   219 a.a.
NCBI ID   WP_033560344.1    Uniprot ID   -
Organism   Escherichia coli strain 20     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 4090628..4101287
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IPT86_RS19720 (IPT86_19720) ygiS 4092833..4094440 (-) 1608 WP_075862117.1 ABC transporter substrate-binding protein -
  IPT86_RS19725 (IPT86_19725) ygiV 4094549..4095031 (-) 483 WP_000183492.1 GyrI-like domain-containing protein -
  IPT86_RS19730 (IPT86_19730) ygiW 4095084..4095476 (-) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  IPT86_RS19735 (IPT86_19735) ciaR 4095628..4096287 (+) 660 WP_033560344.1 quorum sensing response regulator transcription factor QseB Regulator
  IPT86_RS19740 (IPT86_19740) qseC 4096284..4097633 (+) 1350 WP_106106772.1 quorum sensing histidine kinase QseC -
  IPT86_RS19745 (IPT86_19745) mdaB 4097743..4098324 (+) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  IPT86_RS19750 (IPT86_19750) ygiN 4098355..4098669 (+) 315 WP_000633738.1 putative quinol monooxygenase -
  IPT86_RS19755 (IPT86_19755) - 4098714..4099601 (-) 888 WP_075862116.1 MurR/RpiR family transcriptional regulator -
  IPT86_RS19760 (IPT86_19760) - 4099598..4100545 (-) 948 WP_001296418.1 iron-siderophore ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24673.60 Da        Isoelectric Point: 6.9850

>NTDB_id=445313 IPT86_RS19735 WP_033560344.1 4095628..4096287(+) (ciaR) [Escherichia coli strain 20]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVVLDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=445313 IPT86_RS19735 WP_033560344.1 4095628..4096287(+) (ciaR) [Escherichia coli strain 20]
ATGCGAATTTTACTGATCGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTATATAGCGCACCTTATGATGCGGTGGTCCTGGATTTAACCT
TACCGGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTTTTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGCAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACGCTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGCAGTGATTTTATTCGTACCGTTCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

35.874

100

0.365