Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   IIE09_RS09995 Genome accession   NZ_CP064825
Coordinates   2018450..2019106 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli UTI89     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013450..2024106
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IIE09_RS09965 yecA 2014702..2015367 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  IIE09_RS09985 pgsA 2016016..2016564 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  IIE09_RS09990 uvrC 2016621..2018453 (-) 1833 WP_001283418.1 excinuclease ABC subunit UvrC Machinery gene
  IIE09_RS09995 letA 2018450..2019106 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  IIE09_RS10000 yecU 2019402..2019578 (+) 177 WP_001307856.1 protein YecU -
  IIE09_RS10005 yecF 2019565..2019789 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  IIE09_RS10010 sdiA 2019857..2020579 (-) 723 WP_001154255.1 transcriptional regulator SdiA -
  IIE09_RS10015 tcyN 2020809..2021561 (-) 753 WP_001273001.1 L-cystine ABC transporter ATP-binding protein TcyN -
  IIE09_RS10020 tcyL 2021558..2022226 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  IIE09_RS10025 dcyD 2022241..2023227 (-) 987 WP_001128237.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=445101 IIE09_RS09995 WP_000611328.1 2018450..2019106(-) (letA) [Escherichia coli UTI89]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=445101 IIE09_RS09995 WP_000611328.1 2018450..2019106(-) (letA) [Escherichia coli UTI89]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482