Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   MGAS1882_RS00605 Genome accession   NC_017053
Coordinates   98744..99178 (+) Length   144 a.a.
NCBI ID   WP_014407215.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS1882     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 93744..104178
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS1882_RS00575 (MGAS1882_0119) - 95427..95792 (+) 366 WP_002986560.1 DUF1033 family protein -
  MGAS1882_RS00580 (MGAS1882_0120) comGA 95885..96809 (+) 925 Protein_81 competence type IV pilus ATPase ComGA -
  MGAS1882_RS00585 (MGAS1882_0121) comYB 96745..97779 (+) 1035 WP_227868709.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGAS1882_RS00590 (MGAS1882_0122) comGC 97781..98107 (+) 327 WP_014407214.1 competence type IV pilus major pilin ComGC Machinery gene
  MGAS1882_RS00595 (MGAS1882_0123) comGD 98082..98510 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  MGAS1882_RS00600 (MGAS1882_0124) comGE 98467..98751 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  MGAS1882_RS00605 (MGAS1882_0125) comYF 98744..99178 (+) 435 WP_014407215.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGAS1882_RS00610 (MGAS1882_0126) comGG 99162..99488 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  MGAS1882_RS00615 (MGAS1882_0127) comYH 99586..100539 (+) 954 WP_014407216.1 class I SAM-dependent methyltransferase Machinery gene
  MGAS1882_RS00620 (MGAS1882_0128) - 100598..101794 (+) 1197 WP_014407217.1 acetate kinase -
  MGAS1882_RS00625 (MGAS1882_0129) - 101981..102289 (+) 309 WP_041174321.1 hypothetical protein -
  MGAS1882_RS00630 (MGAS1882_0130) proC 102372..103142 (-) 771 WP_014407219.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16542.20 Da        Isoelectric Point: 10.0827

>NTDB_id=44509 MGAS1882_RS00605 WP_014407215.1 98744..99178(+) (comYF) [Streptococcus pyogenes MGAS1882]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLALHDQDNWLLFSHQLREELSGARFCKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide


Download         Length: 435 bp        

>NTDB_id=44509 MGAS1882_RS00605 WP_014407215.1 98744..99178(+) (comYF) [Streptococcus pyogenes MGAS1882]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTTGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCTTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGATTTTGCAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGATATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(47-135)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.079

96.528

0.493
  comYF Streptococcus mutans UA159

50.36

96.528

0.486
  comGF Lactococcus lactis subsp. cremoris KW2

46.715

95.139

0.444
  comGF/cglF Streptococcus mitis NCTC 12261

44.776

93.056

0.417
  comGF/cglF Streptococcus pneumoniae Rx1

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae D39

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae R6

43.609

92.361

0.403
  comGF/cglF Streptococcus pneumoniae TIGR4

43.609

92.361

0.403
  comGF/cglF Streptococcus mitis SK321

42.857

92.361

0.396

Multiple sequence alignment