Detailed information NTG0443471

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: IUJ37_RS11635
• Genome accession: NZ_CP064387
• Coordinates: 2302589..2303863 (-)
• Length: 424 a.a.
• NCBI ID: WP_000130305.1
• Uniprot ID: P0A6H2
• Organism: Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2297589..2308863

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ37_RS11625 (IUJ37_11520)	hupB	2299566..2299838 (-)	273	WP_001043542.1	nucleoid-associated protein HU-beta	-
IUJ37_RS11630 (IUJ37_11525)	lon	2300047..2302401 (-)	2355	WP_001295325.1	endopeptidase La	-
IUJ37_RS11635 (IUJ37_11530)	clpX	2302589..2303863 (-)	1275	WP_000130305.1	ATP-dependent protease ATP-binding subunit ClpX	Regulator
IUJ37_RS11640 (IUJ37_11535)	clpP	2303989..2304612 (-)	624	WP_000122253.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
IUJ37_RS11645 (IUJ37_11540)	tig	2304858..2306156 (-)	1299	WP_001198386.1	trigger factor	-
IUJ37_RS11650 (IUJ37_11545)	bolA	2306500..2306817 (-)	318	WP_000973448.1	transcriptional regulator BolA	-
IUJ37_RS11655 (IUJ37_11550)	yajG	2307122..2307700 (+)	579	WP_000473497.1	lipoprotein	-

Sequence

Protein

• Length: 424 a.a.
• Molecular weight: 46356.01 Da
• Isoelectric Point: 4.9982

>NTDB_id=443471 IUJ37_RS11635 WP_000130305.1 2302589..2303863(-) (clpX) [Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376]
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVISHRVETGSGIGFGATVKAKSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALIQILKEPKNALTKQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIDGQSKPLLIYGKPEAQQASGE

Nucleotide

• Length: 1275 bp

>NTDB_id=443471 IUJ37_RS11635 WP_000130305.1 2302589..2303863(-) (clpX) [Escherichia coli O104:H4 strain PartB-EcoliO104H4-RM8376]
ATGACAGATAAACGCAAAGATGGCTCAGGCAAATTGCTGTATTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGTGTTGATTTATGTAACGACATCATTCGCGAAGAGATTAAAG
AAGTTGCACCGCATCGTGAACGCAGTGCGCTACCGACGCCGCATGAAATTCGCAACCACCTGGACGATTACGTTATCGGC
CAGGAACAGGCGAAAAAAGTGCTGGCGGTCGCGGTATACAACCATTACAAACGTCTGCGCAACGGCGATACCAGCAATGG
TGTCGAGTTGGGCAAAAGTAACATTCTGCTGATCGGTCCGACCGGTTCCGGTAAAACGCTGCTGGCTGAAACGCTGGCGC
GCCTGCTGGACGTCCCGTTCACCATGGCCGACGCAACCACGCTGACCGAAGCCGGTTATGTGGGCGAAGACGTTGAAAAC
ATCATTCAGAAACTGTTGCAGAAATGCGACTACGATGTCCAGAAAGCACAGCGTGGTATTGTCTACATCGATGAAATCGA
CAAGATTTCTCGTAAGTCGGACAACCCGTCTATTACCCGTGACGTTTCCGGTGAAGGCGTACAGCAGGCACTGTTGAAAC
TGATCGAAGGTACTGTTGCTGCCGTTCCACCGCAGGGCGGGCGTAAGCATCCGCAGCAGGAATTTTTGCAGGTTGATACC
TCCAAGATCCTGTTTATTTGTGGCGGTGCGTTTGCCGGTCTGGATAAAGTGATTTCCCACCGTGTAGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTAAAAGCGAAGTCCGACAAAGCAAGCGAAGGCGAGCTGCTGGCGCAGGTTGAACCGGAAG
ATCTGATCAAGTTTGGTCTTATCCCTGAGTTCATTGGTCGTCTGCCGGTTGTCGCAACGTTGAATGAACTGAGCGAAGAA
GCTCTGATTCAGATCCTCAAAGAGCCGAAAAACGCCCTGACCAAGCAGTATCAGGCGCTGTTTAATCTGGAAGGCGTGGA
TCTGGAATTCCGTGACGAGGCGCTGGATGCTATCGCTAAGAAAGCGATGGCGCGTAAAACCGGTGCCCGTGGCCTGCGTT
CCATCGTAGAAGCCGCACTGCTCGATACCATGTACGATCTGCCGTCCATGGAAGACGTCGAAAAAGTGGTTATCGACGAG
TCGGTAATTGATGGTCAAAGCAAACCGTTGCTGATTTATGGTAAGCCGGAAGCGCAACAGGCATCTGGTGAATAA

Domains

Predicted by InterProScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (13-50)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (317-395)

• AAA domain (Cdc48 subfamily) (AAA_2) (112-310)

3D structure

• AlphaFold DB: P0A6H2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	59.85	94.575	0.566
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	55.392	96.226	0.533