Detailed information NTG0443469

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: HKM25_RS10025
• Genome accession: NZ_CP053210
• Coordinates: 1959707..1960717 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain 6A-10
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1954707..1965717

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HKM25_RS10000 (HKM25_2049)	-	1955873..1956166 (-)	294	WP_000977368.1	hypothetical protein	-
HKM25_RS10005 (HKM25_2050)	-	1956328..1956780 (+)	453	WP_000079148.1	universal stress protein	-
HKM25_RS10010 (HKM25_2051)	-	1956815..1958203 (-)	1389	WP_000453143.1	Cof-type HAD-IIB family hydrolase	-
HKM25_RS10015 (HKM25_2052)	-	1958269..1959231 (+)	963	WP_001124777.1	asparaginase	-
HKM25_RS10020 (HKM25_2053)	-	1959260..1959643 (-)	384	WP_001092044.1	hypothetical protein	-
HKM25_RS10025 (HKM25_2054)	ccpA	1959707..1960717 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
HKM25_RS10030 (HKM25_2055)	-	1961141..1961740 (-)	600	WP_000866698.1	response regulator transcription factor	-
HKM25_RS10035 (HKM25_2056)	-	1961741..1962838 (-)	1098	WP_000893537.1	sensor histidine kinase	-
HKM25_RS10040 (HKM25_2057)	-	1962838..1963575 (-)	738	WP_001809843.1	ABC transporter permease	-
HKM25_RS10045 (HKM25_2058)	-	1963577..1964461 (-)	885	WP_000219347.1	ABC transporter ATP-binding protein	-
HKM25_RS10050 (HKM25_2059)	-	1964448..1964642 (-)	195	WP_000820187.1	hypothetical protein	-
HKM25_RS10055	-	1964639..1964845 (-)	207	Protein_1987	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=443469 HKM25_RS10025 WP_000990607.1 1959707..1960717(-) (ccpA) [Streptococcus pneumoniae strain 6A-10]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=443469 HKM25_RS10025 WP_000990607.1 1959707..1960717(-) (ccpA) [Streptococcus pneumoniae strain 6A-10]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCAAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568