Detailed information NTG0443111

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: IUJ41_RS10195
• Genome accession: NZ_CP064365
• Coordinates: 2016421..2017410 (+)
• Length: 329 a.a.
• NCBI ID: WP_000219066.1
• Uniprot ID: P67655
• Organism: Staphylococcus aureus strain PartF-Saureus-RM8376
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 2011421..2022410

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IUJ41_RS10170 (IUJ41_10140)	-	2012485..2012976 (+)	492	WP_000383814.1	DUF948 domain-containing protein	-
IUJ41_RS10175 (IUJ41_10145)	-	2013050..2014090 (+)	1041	WP_000193921.1	hypothetical protein	-
IUJ41_RS10180 (IUJ41_10150)	-	2014225..2014329 (+)	105	WP_001791758.1	hypothetical protein	-
IUJ41_RS10185 (IUJ41_10155)	-	2014790..2015881 (+)	1092	WP_000066378.1	bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase	-
IUJ41_RS10190 (IUJ41_10160)	-	2016235..2016348 (+)	114	WP_001788994.1	hypothetical protein	-
IUJ41_RS10195 (IUJ41_10165)	ccpA	2016421..2017410 (+)	990	WP_000219066.1	catabolite control protein A	Regulator
IUJ41_RS10200 (IUJ41_10170)	-	2017508..2018677 (-)	1170	WP_001184005.1	acetoin utilization protein AcuC	-
IUJ41_RS10205 (IUJ41_10175)	-	2018702..2019334 (-)	633	WP_001015996.1	hypothetical protein	-
IUJ41_RS10210 (IUJ41_10180)	acsA	2019503..2021209 (+)	1707	WP_000862083.1	acetate--CoA ligase	-

Sequence

Protein

• Length: 329 a.a.
• Molecular weight: 36060.24 Da
• Isoelectric Point: 5.5054

>NTDB_id=443111 IUJ41_RS10195 WP_000219066.1 2016421..2017410(+) (ccpA) [Staphylococcus aureus strain PartF-Saureus-RM8376]
MTVTIYDVAREARVSMATVSRVVNGNQNVKAETKNKVNEVIKRLNYRPNAVARGLASKKTTTVGVIIPDISNIYYSQLAR
GLEDIATMYKYHSIISNSDNDPEKEKEIFNNLLSKQVDGIIFLGGTITEEMKELINQSSVPVVVSGTNGKDAHIASVNID
FTEAAKEITGELIEKGAKSFALVGGEHSKKAQEDVLEGLTEVLNKNGLQLGDTLNCSGAESYKEGVKAFAKMKGNLPDAI
LCISDEEAIGIMHSAMDAGIKVPEELQIISFNNTRLVEMVRPQLSSVIQPLYDIGAVGMRLLTKYMNDEKIEEPNVVLPH
RIEYRGTTK

Nucleotide

• Length: 990 bp

>NTDB_id=443111 IUJ41_RS10195 WP_000219066.1 2016421..2017410(+) (ccpA) [Staphylococcus aureus strain PartF-Saureus-RM8376]
ATGACAGTTACTATATATGATGTAGCAAGAGAAGCGCGTGTCTCTATGGCCACAGTGTCGCGTGTTGTTAATGGGAACCA
AAATGTTAAAGCAGAAACTAAAAATAAAGTTAACGAAGTCATTAAGCGTTTGAATTATCGTCCAAATGCTGTTGCTAGAG
GTTTAGCTAGTAAAAAGACAACAACAGTAGGTGTGATCATTCCAGATATATCTAATATCTATTATTCACAACTTGCTCGT
GGACTTGAAGATATTGCAACAATGTATAAATATCACTCAATTATTTCAAATTCAGATAACGATCCTGAAAAGGAAAAAGA
AATTTTTAATAACTTATTAAGTAAACAGGTTGATGGTATTATTTTCCTTGGTGGTACAATTACTGAAGAAATGAAAGAAT
TGATAAATCAATCATCTGTACCTGTAGTAGTATCAGGAACAAATGGTAAGGATGCACATATAGCATCAGTTAATATTGAT
TTTACTGAAGCTGCGAAAGAAATTACGGGAGAATTAATTGAAAAAGGCGCTAAATCATTTGCTTTAGTAGGTGGAGAACA
TTCTAAAAAAGCTCAAGAAGATGTTTTAGAAGGTTTAACTGAAGTGTTAAATAAAAATGGCCTTCAATTAGGTGATACAT
TGAATTGTTCTGGTGCTGAAAGTTATAAAGAAGGCGTAAAAGCTTTTGCCAAAATGAAAGGCAATTTGCCAGATGCCATT
TTATGTATCAGCGACGAAGAAGCAATTGGTATTATGCATAGTGCAATGGATGCTGGTATTAAAGTTCCAGAGGAATTACA
AATTATTAGTTTCAATAATACACGATTAGTTGAGATGGTTAGACCACAACTTTCTAGTGTTATTCAACCATTATATGATA
TCGGTGCAGTAGGGATGCGCTTATTAACAAAATATATGAACGATGAAAAGATAGAAGAACCAAATGTAGTTTTACCTCAC
AGAATTGAATACCGAGGAACTACAAAATAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (4-49)

• Periplasmic binding protein-like domain (Peripla_BP_3) (171-328)

3D structure

• AlphaFold DB: P67655

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	47.879	100	0.48
ccpA	Streptococcus gordonii str. Challis substr. CH1	47.112	100	0.471
ccpA	Streptococcus pneumoniae D39	46.201	100	0.462