Detailed information NTG0044246

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: HMPREF1038_RS09675
• Genome accession: NC_018630
• Coordinates: 1803518..1804417 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904850.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae gamPNI0373
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1798518..1809417

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HMPREF1038_RS09650 (HMPREF1038_01968)	rsmA	1799168..1800040 (-)	873	WP_001216845.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
HMPREF1038_RS09655 (HMPREF1038_01969)	-	1800291..1800584 (-)	294	Protein_1827	hypothetical protein	-
HMPREF1038_RS09660 (HMPREF1038_01970)	-	1800577..1801218 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
HMPREF1038_RS09670 (HMPREF1038_01971)	-	1801220..1803249 (-)	2030	Protein_1829	bacteriocin-associated integral membrane family protein	-
HMPREF1038_RS09675 (HMPREF1038_01973)	comR	1803518..1804417 (-)	900	WP_000904850.1	helix-turn-helix transcriptional regulator	Regulator
HMPREF1038_RS09680 (HMPREF1038_01974)	rnmV	1804489..1805049 (-)	561	WP_000660013.1	ribonuclease M5	-
HMPREF1038_RS09685 (HMPREF1038_01975)	-	1805049..1805822 (-)	774	WP_000575634.1	TatD family hydrolase	-
HMPREF1038_RS09690 (HMPREF1038_01976)	-	1806127..1806845 (-)	719	Protein_1833	DUF1542 domain-containing protein	-
HMPREF1038_RS09695 (HMPREF1038_01978)	rpmH	1807049..1807183 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
HMPREF1038_RS09700 (HMPREF1038_01979)	-	1807328..1808542 (-)	1215	WP_001844920.1	pyridoxal phosphate-dependent aminotransferase	-
HMPREF1038_RS09705 (HMPREF1038_01980)	-	1808698..1808991 (-)	294	WP_000977364.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35409.16 Da
• Isoelectric Point: 4.7732

>NTDB_id=44246 HMPREF1038_RS09675 WP_000904850.1 1803518..1804417(-) (comR) [Streptococcus pneumoniae gamPNI0373]
MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPSLPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMSQIIEKEVYSTNDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQLIGDEFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=44246 HMPREF1038_RS09675 WP_000904850.1 1803518..1804417(-) (comR) [Streptococcus pneumoniae gamPNI0373]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGA
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGACTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTCCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGTCTCAGATCATAGAAAAAGAAGTTTATTCAACAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGAAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGCAGCTAATTGGAGATGAATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.457	97.324	0.365
comR	Streptococcus suis 05ZYH33	37.457	97.324	0.365
comR	Streptococcus pyogenes MGAS8232	36.577	99.666	0.365