Detailed information NTG0438437

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: HC661_RS16825
• Genome accession: NZ_CP051463
• Coordinates: 3438628..3439791 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain UCMB5140
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3433628..3444791

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HC661_RS16795 (HC661_32330)	-	3433895..3434313 (-)	419	Protein_3263	TIGR03826 family flagellar region protein	-
HC661_RS16800 (HC661_32340)	comFC	3434387..3435076 (-)	690	WP_196493397.1	phosphoribosyltransferase family protein	Machinery gene
HC661_RS16805 (HC661_32350)	-	3435082..3435366 (-)	285	WP_003151389.1	competence protein ComFB	-
HC661_RS16810	-	3435424..3436808 (-)	1385	Protein_3266	DEAD/DEAH box helicase	-
HC661_RS16815 (HC661_32370)	-	3436916..3437764 (-)	849	WP_015418336.1	DegV family protein	-
HC661_RS16820 (HC661_32380)	degU	3437862..3438551 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
HC661_RS16825 (HC661_32390)	degS	3438628..3439791 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
HC661_RS16830 (HC661_32400)	-	3440014..3440661 (+)	648	WP_003151384.1	YigZ family protein	-
HC661_RS16835 (HC661_32410)	-	3440666..3441880 (+)	1215	WP_015418337.1	LCP family protein	-
HC661_RS16840 (HC661_32420)	-	3441970..3443046 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
HC661_RS16845 (HC661_32430)	-	3443179..3444375 (-)	1197	WP_015418338.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=438437 HC661_RS16825 WP_007407484.1 3438628..3439791(-) (degS) [Bacillus velezensis strain UCMB5140]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=438437 HC661_RS16825 WP_007407484.1 3438628..3439791(-) (degS) [Bacillus velezensis strain UCMB5140]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGTAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951