Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   FOI11_RS20625 Genome accession   NZ_CP063369
Coordinates   4315714..4316373 (-) Length   219 a.a.
NCBI ID   WP_032176610.1    Uniprot ID   -
Organism   Escherichia coli strain 1409     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 4310714..4321373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FOI11_RS20600 (FOI11_020600) parE 4310803..4312695 (+) 1893 WP_000195296.1 DNA topoisomerase IV subunit B -
  FOI11_RS20605 (FOI11_020605) ygiN 4312743..4313057 (-) 315 WP_000958598.1 putative quinol monooxygenase -
  FOI11_RS20610 (FOI11_020610) mdaB 4313088..4313669 (-) 582 WP_000065430.1 NADPH:quinone oxidoreductase MdaB -
  FOI11_RS20615 (FOI11_020615) ygiZ 4313988..4314322 (+) 335 Protein_4073 DUF2645 family protein -
  FOI11_RS20620 (FOI11_020620) qseC 4314368..4315717 (-) 1350 WP_000673402.1 quorum sensing histidine kinase QseC -
  FOI11_RS20625 (FOI11_020625) ciaR 4315714..4316373 (-) 660 WP_032176610.1 quorum sensing response regulator transcription factor QseB Regulator
  FOI11_RS20630 (FOI11_020630) ygiW 4316525..4316917 (+) 393 WP_000712658.1 OB fold stress tolerance protein YgiW -
  FOI11_RS20635 (FOI11_020635) ygiV 4316970..4317452 (+) 483 WP_000183505.1 GyrI-like domain-containing protein -
  FOI11_RS20640 (FOI11_020640) mqsR 4317657..4317953 (+) 297 WP_000415584.1 type II toxin-antitoxin system toxin MqsR -
  FOI11_RS20645 (FOI11_020645) mqsA 4317955..4318350 (+) 396 WP_000650107.1 type II toxin-antitoxin system antitoxin MqsA -
  FOI11_RS20650 (FOI11_020650) ygiS 4318483..4320090 (+) 1608 WP_001295629.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24699.68 Da        Isoelectric Point: 6.9850

>NTDB_id=438158 FOI11_RS20625 WP_032176610.1 4315714..4316373(-) (ciaR) [Escherichia coli strain 1409]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLPGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYILGEK

Nucleotide


Download         Length: 660 bp        

>NTDB_id=438158 FOI11_RS20625 WP_032176610.1 4315714..4316373(-) (ciaR) [Escherichia coli strain 1409]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACCAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGTT
ACATATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(145-216)

Response regulator receiver domain (Response_reg)

(3-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus pneumoniae Rx1

38.326

100

0.397
  ciaR Streptococcus pneumoniae D39

38.326

100

0.397
  ciaR Streptococcus pneumoniae R6

38.326

100

0.397
  ciaR Streptococcus pneumoniae TIGR4

38.326

100

0.397
  ciaR Streptococcus mutans UA159

36.323

100

0.37