Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   HEP75_RS05435 Genome accession   NZ_CP051261
Coordinates   1277729..1279117 (-) Length   462 a.a.
NCBI ID   WP_185822434.1    Uniprot ID   A0A7G7STX4
Organism   Xanthomonas sp. SI     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1269524..1285153 1277729..1279117 within 0


Gene organization within MGE regions


Location: 1269524..1285153
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HEP75_RS05405 (HEP75_01059) - 1269524..1270684 (+) 1161 WP_185825706.1 DegT/DnrJ/EryC1/StrS family aminotransferase -
  HEP75_RS05410 (HEP75_01060) - 1270671..1271882 (-) 1212 WP_221899305.1 hypothetical protein -
  HEP75_RS05415 - 1271890..1272588 (-) 699 WP_185825708.1 class I SAM-dependent methyltransferase -
  HEP75_RS05420 (HEP75_01063) - 1273498..1274646 (-) 1149 WP_185825709.1 glycosyltransferase -
  HEP75_RS05425 (HEP75_01064) - 1274888..1275745 (-) 858 WP_185825710.1 glycosyltransferase family 2 protein -
  HEP75_RS05430 (HEP75_01065) pilB 1275896..1277635 (+) 1740 WP_185825711.1 type IV-A pilus assembly ATPase PilB Machinery gene
  HEP75_RS05435 (HEP75_01066) pilR 1277729..1279117 (-) 1389 WP_185822434.1 sigma-54 dependent transcriptional regulator Regulator
  HEP75_RS05440 (HEP75_01067) - 1279191..1280804 (-) 1614 WP_185825712.1 HAMP domain-containing sensor histidine kinase -
  HEP75_RS05445 (HEP75_01068) sucC 1281104..1282267 (+) 1164 WP_179566646.1 ADP-forming succinate--CoA ligase subunit beta -
  HEP75_RS05450 (HEP75_01069) sucD 1282291..1283163 (+) 873 WP_179566644.1 succinate--CoA ligase subunit alpha -
  HEP75_RS05455 (HEP75_01070) - 1283246..1285153 (+) 1908 WP_185825713.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 462 a.a.        Molecular weight: 49851.29 Da        Isoelectric Point: 6.5828

>NTDB_id=437132 HEP75_RS05435 WP_185822434.1 1277729..1279117(-) (pilR) [Xanthomonas sp. SI]
MNETRSALVVDDERDIRELLVLTLGRMGLRISTAANLAEARELLASNPYDLCITDMRLPDGNGIELVSEIARHYPRTPVA
MITAFGSMDLAVEALKAGAFDFVSKPVDIHVLRGLVRHALELNNSERAAPPAPPPEQASRLLGASAAMDVLRATIAKVAR
SQAPVYILGESGVGKELVARTIHEQGARAAGPFVPVNCGAIPAELMESEFFGHKKGSFTGAHADQAGLFQAAHGGTLFLD
EVAELPLPMQVKLLRAIQEKSVRPVGASIEVPTDVRILSATHKDLADLVADGRFRHDLYYRINVIELRVPPLRDRGGDLP
QLAAAILARLAKSHGRVTPLLSPSALDALNRYAFPGNVRELENILERALAMAEDDQISAADLHLPQPGNSARAAAEAAPA
LPPGVVDIDPTSSALPSYIEQLERAAIQKALEENRWNKTRTAAQLGITFRALRYKLKKLGME

Nucleotide


Download         Length: 1389 bp        

>NTDB_id=437132 HEP75_RS05435 WP_185822434.1 1277729..1279117(-) (pilR) [Xanthomonas sp. SI]
ATGAACGAAACCCGAAGCGCCCTGGTCGTCGACGACGAACGCGACATCCGCGAGCTGCTGGTGCTGACCCTGGGCAGGAT
GGGGCTGCGCATCAGCACCGCCGCCAACCTCGCCGAAGCCCGCGAACTGCTGGCCAGCAATCCCTACGACCTGTGCATCA
CCGACATGCGCCTGCCCGACGGCAACGGCATCGAGCTAGTCAGCGAGATCGCCCGCCACTACCCGCGCACGCCGGTGGCG
ATGATCACCGCCTTCGGCAGCATGGACCTGGCGGTGGAAGCGCTGAAGGCCGGCGCCTTCGACTTCGTCAGCAAGCCGGT
GGACATCCACGTGCTGCGCGGCCTGGTCAGGCACGCGCTGGAACTCAACAACAGCGAACGCGCCGCGCCGCCGGCGCCGC
CGCCGGAACAGGCCAGCCGCCTGCTCGGCGCCTCGGCGGCGATGGACGTGCTGCGCGCCACCATCGCCAAGGTCGCGCGC
AGCCAGGCGCCGGTCTACATCCTCGGCGAGTCCGGGGTCGGCAAGGAACTGGTCGCACGTACCATCCACGAACAGGGCGC
GCGCGCGGCCGGGCCGTTCGTGCCGGTCAACTGCGGCGCGATCCCGGCCGAACTGATGGAAAGCGAGTTCTTCGGCCACA
AGAAAGGCAGCTTCACCGGCGCCCATGCCGACCAGGCCGGTCTGTTCCAGGCCGCGCACGGCGGCACCCTGTTCCTGGAC
GAAGTCGCCGAGCTGCCGCTGCCGATGCAGGTCAAGCTGCTGCGCGCGATCCAGGAGAAGTCGGTGCGCCCGGTCGGTGC
CTCGATCGAAGTGCCGACCGACGTGCGCATCCTCTCGGCCACGCACAAGGACCTGGCCGACCTGGTCGCCGACGGCCGCT
TCCGCCACGACCTGTACTACCGCATCAACGTGATCGAACTGCGCGTGCCGCCGCTGCGCGACCGCGGCGGCGACCTGCCG
CAACTGGCCGCGGCGATCCTGGCGCGGCTGGCCAAGAGCCACGGCCGGGTCACCCCGCTGCTGTCGCCGTCGGCGCTGGA
CGCGCTGAACCGCTACGCCTTCCCCGGCAACGTGCGCGAACTGGAGAACATCCTCGAGCGCGCCCTGGCGATGGCCGAAG
ACGACCAGATCAGCGCCGCCGATCTGCACCTGCCGCAGCCCGGCAACAGCGCCCGCGCCGCCGCCGAAGCCGCCCCCGCG
CTGCCGCCCGGCGTGGTCGACATCGACCCGACCTCCTCCGCCCTGCCCTCCTACATCGAGCAACTCGAGCGCGCCGCGAT
CCAGAAGGCGCTGGAAGAGAACCGCTGGAACAAGACCCGCACCGCGGCGCAGCTCGGCATCACGTTTCGTGCGCTGCGCT
ACAAGCTCAAGAAGTTGGGGATGGAGTAG

Domains

Predicted by InterproScan.

Sigma-54 interaction domain (Sigma54_activat)

(142-307)

Bacterial regulatory protein, Fis family (HTH_8)

(419-459)

Response regulator receiver domain (Response_reg)

(8-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G7STX4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

62.092

99.351

0.617
  pilR Acinetobacter baumannii strain A118

46.681

100

0.472