Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   HIB_RS05775 Genome accession   NC_016809
Coordinates   1121787..1122461 (+) Length   224 a.a.
NCBI ID   WP_005647998.1    Uniprot ID   Q4QLV0
Organism   Haemophilus influenzae 10810     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1116787..1127461
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HIB_RS05740 (HIB_10890) rpmG 1117704..1117874 (-) 171 WP_005613503.1 50S ribosomal protein L33 -
  HIB_RS05745 (HIB_10900) rpmB 1117886..1118122 (-) 237 WP_005542826.1 50S ribosomal protein L28 -
  HIB_RS05750 (HIB_10910) radC 1118336..1119001 (-) 666 WP_013527272.1 RadC family protein -
  HIB_RS05755 (HIB_10920) coaBC 1119164..1120366 (+) 1203 WP_015701964.1 bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC -
  HIB_RS05760 (HIB_10930) dut 1120414..1120869 (+) 456 WP_005631431.1 dUTP diphosphatase -
  HIB_RS05765 (HIB_10940) slmA 1120873..1121529 (+) 657 WP_005648000.1 nucleoid occlusion factor SlmA -
  HIB_RS05770 (HIB_10950) - 1121551..1121802 (+) 252 WP_005647999.1 YheU family protein -
  HIB_RS05775 (HIB_10960) crp 1121787..1122461 (+) 675 WP_005647998.1 cAMP-activated global transcriptional regulator CRP Regulator
  HIB_RS05780 (HIB_10970) rlmC 1122826..1124004 (-) 1179 WP_015701965.1 23S rRNA (uracil(747)-C(5))-methyltransferase RlmC -
  HIB_RS05785 (HIB_10980) nagZ 1124001..1125053 (-) 1053 WP_041175055.1 beta-N-acetylhexosaminidase -
  HIB_RS05790 (HIB_10990) - 1125057..1125407 (-) 351 WP_005647993.1 YcfL family protein -
  HIB_RS05795 (HIB_11000) hinT 1125407..1125757 (-) 351 WP_005627389.1 purine nucleoside phosphoramidase -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25151.85 Da        Isoelectric Point: 6.8375

>NTDB_id=43618 HIB_RS05775 WP_005647998.1 1121787..1122461(+) (crp) [Haemophilus influenzae 10810]
MSNELTEIDEVVTSSQEEATQRDPVLDWFLTHCHLHKYPAKSTLIHAGEDATTLYYVIKGSVMVSSKDDEGKEMILTYLG
AGQFFGEAGLFDEGSKRSAWVKTKTTCEIAEISYKKYRQLIQANPEILMFLTAQLARRLQNTSRQVTNLAFLDVAGRIAQ
TLMNLAKQPEAMTHPDGMQIKITRQEIGQMVGCSRETVGRIIKMLEDQNLIHAHGKTIVVYGAR

Nucleotide


Download         Length: 675 bp        

>NTDB_id=43618 HIB_RS05775 WP_005647998.1 1121787..1122461(+) (crp) [Haemophilus influenzae 10810]
ATGTCAAATGAATTAACCGAAATTGATGAAGTTGTAACCTCCTCTCAAGAAGAAGCAACTCAACGAGATCCCGTTTTAGA
TTGGTTTCTTACTCACTGCCATTTGCATAAATATCCTGCAAAATCAACTTTAATTCATGCTGGGGAAGATGCGACCACGC
TGTATTATGTAATTAAAGGTTCTGTAATGGTATCTTCAAAAGATGATGAAGGCAAAGAGATGATCCTCACTTACTTAGGT
GCAGGACAATTTTTTGGCGAAGCTGGATTATTTGATGAAGGTTCAAAACGATCAGCTTGGGTAAAAACAAAAACAACATG
TGAAATTGCTGAAATTTCCTATAAGAAATATCGCCAGTTGATTCAGGCAAACCCTGAAATCTTAATGTTTCTCACTGCAC
AATTGGCAAGACGTTTGCAAAATACATCACGTCAAGTCACGAATTTGGCATTTTTAGACGTTGCAGGTCGCATCGCTCAA
ACTTTAATGAACTTAGCTAAACAGCCTGAAGCAATGACGCATCCTGATGGTATGCAAATCAAAATTACACGCCAAGAAAT
AGGGCAAATGGTGGGTTGTTCACGAGAAACTGTGGGGCGCATTATTAAGATGTTGGAGGATCAGAATCTTATCCACGCTC
ATGGAAAAACAATCGTTGTATATGGCGCAAGATAA

Domains

Predicted by InterproScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(36-124)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(156-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QLV0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Haemophilus influenzae Rd KW20

100

100

1
  crp Vibrio cholerae strain A1552

75.49

91.071

0.687
  crp Acinetobacter baumannii D1279779

48.705

86.161

0.42

Multiple sequence alignment