Detailed information NTG0435393

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: HEQ84_RS08810
• Genome accession: NZ_CP050870
• Coordinates: 1702788..1703888 (-)
• Length: 366 a.a.
• NCBI ID: WP_120764773.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain CS6
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1697788..1708888

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HEQ84_RS08765	-	1698112..1698387 (-)	276	WP_011681681.1	hypothetical protein	-
HEQ84_RS08770 (HEQ84_08780)	-	1698399..1698597 (-)	199	Protein_1681	helix-turn-helix transcriptional regulator	-
HEQ84_RS08775 (HEQ84_08785)	-	1698846..1700039 (-)	1194	WP_014608740.1	acetate kinase	-
HEQ84_RS08780 (HEQ84_08790)	comYH	1700095..1701051 (-)	957	WP_011681684.1	class I SAM-dependent methyltransferase	Machinery gene
HEQ84_RS08785 (HEQ84_08795)	comGG	1701096..1701413 (-)	318	WP_011681685.1	competence type IV pilus minor pilin ComGG	-
HEQ84_RS08790 (HEQ84_08800)	comYF	1701391..1701828 (-)	438	WP_011681686.1	competence type IV pilus minor pilin ComGF	Machinery gene
HEQ84_RS08795 (HEQ84_08805)	comGE	1701812..1702105 (-)	294	WP_024704238.1	competence type IV pilus minor pilin ComGE	-
HEQ84_RS08800 (HEQ84_08810)	comYD	1702077..1702505 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
HEQ84_RS08805 (HEQ84_08815)	comYC	1702465..1702791 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
HEQ84_RS08810 (HEQ84_08820)	comYB	1702788..1703888 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
HEQ84_RS08815 (HEQ84_08825)	comGA/cglA/cilD	1703770..1704711 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
HEQ84_RS08820 (HEQ84_08830)	-	1704792..1705154 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

• Length: 366 a.a.
• Molecular weight: 41876.03 Da
• Isoelectric Point: 10.1377

>NTDB_id=435393 HEQ84_RS08810 WP_120764773.1 1702788..1703888(-) (comYB) [Streptococcus thermophilus strain CS6]
MPEKISKTIRRPTGISSWKVWLNKDVSLRGISKGKKLKISQQVKVIQLFKQLLKAGFTLTEIVAFLERSHLLKETSLSLM
KESLIRGDRLYQMLALVGFSDNIVTQISLADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKNNWAVQLVQIFPQLFFVSLCGLLVLGLILYLWVKRQSALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGVDLLDLVALMQEQKSKLFRELGADLEEALMLGQSFPERIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QNFFNRLNKATTFVQPLIFVIVAVVIVMIYVAMLLPMYQNMEGMMS

Nucleotide

• Length: 1101 bp

>NTDB_id=435393 HEQ84_RS08810 WP_120764773.1 1702788..1703888(-) (comYB) [Streptococcus thermophilus strain CS6]
TTGCCAGAGAAAATTTCCAAAACCATTCGTCGACCAACTGGAATCAGCAGTTGGAAGGTTTGGTTAAACAAGGATGTCTC
ACTGAGAGGGATATCCAAGGGGAAAAAATTAAAGATTAGTCAGCAAGTTAAGGTTATCCAGCTCTTCAAACAACTTTTAA
AGGCCGGTTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGCTGAAAGAAACATCCTTGTCTCTTATG
AAAGAGAGTTTAATACGCGGTGATAGGTTGTATCAGATGTTAGCGTTAGTGGGGTTTTCGGACAATATTGTTACTCAGAT
TTCTCTTGCTGACAAGCACGGTAATCTTCTAGGGAGTCTAACAAAGATTGAAACCTATATGCTTCGTATGACAAAGGTTC
GCAAGAAACTCATGGAGGTGGCGACTTATCCCATACTACTTCTGGGTTTTCTGATTCTGATTATGCTAGGACTTAAAAAT
TATCTTCTACCCCAACTCTTAGAGGGTGATGGTAAGAATAATTGGGCTGTACAGTTGGTTCAAATTTTTCCCCAGCTTTT
TTTTGTGAGTTTGTGTGGACTCCTTGTGTTGGGTTTAATTCTCTATCTATGGGTGAAACGACAGTCAGCCCTTGTTTTTT
ATAGGCGAATGGCCAAAATCCCTTTTATTGGTCAGACAGTAAGGCTTTACACGACCGCCTATTATGCTAGGGAATGGGGA
AATTTATTAGGTCAAGGCGTTGATTTGCTAGATTTGGTGGCTCTTATGCAAGAGCAAAAGTCTAAACTCTTCCGTGAGCT
GGGAGCCGATTTGGAAGAAGCCCTGATGCTGGGACAGAGTTTTCCTGAACGTATTGCCAGTCATCCGTTTTTTACTAAGG
AGCTCTCACTAATTATTGCTTATGGGGAGGCCAATGCGAGGTTGGGCTATGAGTTGGAAGTTTATGCCGAGGAGGTTTGG
CAAAACTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCAGTTGTGATTGT
AATGATCTATGTAGCCATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (236-356)

• Type II secretion system (T2SS), protein F (T2SSF) (51-164)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.678	93.443	0.511
comYB	Streptococcus mutans UA159	54.678	93.443	0.511
comYB	Streptococcus gordonii str. Challis substr. CH1	51.17	93.443	0.478
comGB/cglB	Streptococcus mitis NCTC 12261	50.453	90.437	0.456
comGB/cglB	Streptococcus mitis SK321	49.697	90.164	0.448
comGB/cglB	Streptococcus pneumoniae Rx1	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae D39	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae R6	49.695	89.617	0.445
comGB/cglB	Streptococcus pneumoniae TIGR4	49.695	89.617	0.445
comGB	Lactococcus lactis subsp. cremoris KW2	45.758	90.164	0.413