Detailed information NTG0435362

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: HEQ84_RS03260
• Genome accession: NZ_CP050870
• Coordinates: 600719..601720 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain CS6
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 595719..606720

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HEQ84_RS03240 (HEQ84_03215)	smpB	596826..597290 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
HEQ84_RS03245 (HEQ84_03220)	-	597444..598850 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
HEQ84_RS03250 (HEQ84_03225)	-	598852..599217 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
HEQ84_RS03255 (HEQ84_03230)	-	599320..600405 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
HEQ84_RS03260 (HEQ84_03235)	ccpA	600719..601720 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
HEQ84_RS03265 (HEQ84_03240)	-	601779..601976 (+)	198	WP_014608125.1	hypothetical protein	-
HEQ84_RS03270	-	602082..602306 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
HEQ84_RS03275 (HEQ84_03245)	-	602307..602846 (+)	540	WP_011680936.1	hypothetical protein	-
HEQ84_RS03280 (HEQ84_03250)	-	602859..603974 (+)	1116	WP_011680937.1	glycerate kinase	-
HEQ84_RS03285 (HEQ84_03255)	-	604021..604476 (-)	456	WP_011680938.1	YueI family protein	-
HEQ84_RS03290 (HEQ84_03260)	eno	604685..605989 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
HEQ84_RS03295 (HEQ84_03265)	-	606141..606326 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=435362 HEQ84_RS03260 WP_004197422.1 600719..601720(+) (ccpA) [Streptococcus thermophilus strain CS6]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=435362 HEQ84_RS03260 WP_004197422.1 600719..601720(+) (ccpA) [Streptococcus thermophilus strain CS6]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547