Detailed information NTG0435295

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: IMP69_RS18365
• Genome accession: NZ_CP062876
• Coordinates: 3751137..3751796 (-)
• Length: 219 a.a.
• NCBI ID: WP_001221487.1
• Uniprot ID: -
• Organism: Escherichia coli O157:H16 strain Res13-Lact-PEA12-26
• Function: repress competence development; post-transcriptional repression of CSP production (predicted from homology) Competence regulation

Genomic Context

Location: 3746137..3756796

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IMP69_RS18340 (IMP69_18345)	ygiN	3747038..3747352 (-)	315	WP_000958600.1	putative quinol monooxygenase	-
IMP69_RS18345 (IMP69_18350)	mdaB	3747383..3747964 (-)	582	WP_000065430.1	NADPH:quinone oxidoreductase MdaB	-
IMP69_RS25890	-	3748214..3748693 (+)	480	WP_000065333.1	Hcp family type VI secretion system effector	-
IMP69_RS25895	-	3748696..3749406 (+)	711	WP_000834020.1	hypothetical protein	-
IMP69_RS18355 (IMP69_18360)	ygiZ	3749413..3749745 (+)	333	WP_000914691.1	DUF2645 family protein	-
IMP69_RS18360 (IMP69_18365)	qseC	3749791..3751140 (-)	1350	WP_000673404.1	quorum sensing histidine kinase QseC	-
IMP69_RS18365 (IMP69_18370)	ciaR	3751137..3751796 (-)	660	WP_001221487.1	quorum sensing response regulator transcription factor QseB	Regulator
IMP69_RS18370 (IMP69_18375)	ygiW	3751948..3752340 (+)	393	WP_000712658.1	OB fold stress tolerance protein YgiW	-
IMP69_RS18375 (IMP69_18380)	ygiV	3752393..3752875 (+)	483	WP_000183505.1	GyrI-like domain-containing protein	-
IMP69_RS18380 (IMP69_18385)	mqsR	3753080..3753376 (+)	297	WP_000415584.1	type II toxin-antitoxin system toxin MqsR	-
IMP69_RS18385 (IMP69_18390)	mqsA	3753378..3753773 (+)	396	WP_000650107.1	type II toxin-antitoxin system antitoxin MqsA	-
IMP69_RS18390 (IMP69_18395)	ygiS	3753906..3755513 (+)	1608	WP_001295629.1	ABC transporter substrate-binding protein	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24703.67 Da
• Isoelectric Point: 6.9850

>NTDB_id=435295 IMP69_RS18365 WP_001221487.1 3751137..3751796(-) (ciaR) [Escherichia coli O157:H16 strain Res13-Lact-PEA12-26]
MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAPYDAVILDLTLLGMDGRDILREWREKGQREPVLILTA
RDALAERVEGLRLGADDYLCKPFALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGEK

Nucleotide

• Length: 660 bp

>NTDB_id=435295 IMP69_RS18365 WP_001221487.1 3751137..3751796(-) (ciaR) [Escherichia coli O157:H16 strain Res13-Lact-PEA12-26]
ATGCGAATTTTACTGATAGAAGATGACATGCTGATTGGCGACGGCATCAAAACGGGCCTTAGTAAAATGGGTTTTAGCGT
CGACTGGTTTACACAAGGTCGTCAGGGAAAAGAGGCGCTTTATAGCGCACCTTATGATGCGGTGATCCTGGATTTAACCT
TACTAGGCATGGATGGTCGCGATATTTTGCGCGAATGGCGAGAAAAAGGTCAGCGTGAGCCGGTACTGATCCTGACCGCG
CGCGATGCGCTGGCGGAACGTGTAGAAGGGCTGCGTCTGGGAGCTGACGATTATCTGTGTAAACCTTTTGCGTTGATAGA
AGTCGCCGCCAGGCTGGAAGCTCTGATGCGCCGAACCAACGGCCAGGCCAGCAACGAGCTGCGCCACGGTAACGTCATGC
TCGACCCCGGCAAACGTATCGCCACGCTGGCTGGCGAACCCTTAACACTGAAACCAAAAGAATTTGCCCTGCTGGAATTA
CTGATGCGTAACGCTGGTCGGGTACTGCCGCGCAAACTGATTGAAGAGAAACTGTATACCTGGGACGAAGAGGTCACCAG
TAATGCCGTTGAAGTGCATGTGCATCATCTGCGACGCAAACTCGGTAGTGATTTTATTCGTACCGTGCATGGTATTGGCT
ACACATTAGGTGAGAAATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (3-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (145-216)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaR	Streptococcus pneumoniae Rx1	37.885	100	0.393
ciaR	Streptococcus pneumoniae D39	37.885	100	0.393
ciaR	Streptococcus pneumoniae R6	37.885	100	0.393
ciaR	Streptococcus pneumoniae TIGR4	37.885	100	0.393
ciaR	Streptococcus mutans UA159	35.426	100	0.361