Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   SMUGS5_RS03650 Genome accession   NC_018089
Coordinates   751495..753486 (+) Length   663 a.a.
NCBI ID   WP_002264166.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 746495..758486
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS03635 (SMUGS5_03555) - 747253..747993 (-) 741 WP_002264169.1 amino acid ABC transporter ATP-binding protein -
  SMUGS5_RS03640 (SMUGS5_03560) - 747993..750179 (-) 2187 WP_002305309.1 ABC transporter substrate-binding protein/permease -
  SMUGS5_RS03645 - 750370..751286 (+) 917 Protein_704 CPBP family intramembrane glutamic endopeptidase -
  SMUGS5_RS03650 (SMUGS5_03575) uvrB 751495..753486 (+) 1992 WP_002264166.1 excinuclease ABC subunit UvrB Machinery gene
  SMUGS5_RS10740 - 753623..753745 (-) 123 WP_255262718.1 hypothetical protein -
  SMUGS5_RS03655 (SMUGS5_03580) - 753815..754147 (+) 333 WP_002261962.1 hypothetical protein -
  SMUGS5_RS10785 (SMUGS5_03585) - 754147..754260 (+) 114 WP_002264165.1 hypothetical protein -
  SMUGS5_RS03665 (SMUGS5_03590) - 754451..755341 (+) 891 WP_002267623.1 helix-turn-helix transcriptional regulator -
  SMUGS5_RS03670 (SMUGS5_03595) - 755399..755863 (+) 465 WP_002261965.1 8-oxo-dGTP diphosphatase -
  SMUGS5_RS03675 (SMUGS5_03600) - 755971..756786 (+) 816 WP_002261966.1 transporter substrate-binding domain-containing protein -
  SMUGS5_RS03680 (SMUGS5_03605) - 757002..758138 (+) 1137 WP_014834923.1 aminotransferase -

Sequence

Protein


Download         Length: 663 a.a.        Molecular weight: 76024.91 Da        Isoelectric Point: 4.5849

>NTDB_id=43514 SMUGS5_RS03650 WP_002264166.1 751495..753486(+) (uvrB) [Streptococcus mutans GS-5]
MIDRKDNNQFHLVSKYEPSGDQPEAIEALVDNIEGGEKAQILKGATGTGKTYTMSQVIQKVNKPTLVIAHNKTLAGQLYG
EFKEFFPDNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
DSVVSLRPSQEISRDQLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREIESLTGRVL
GEVDHLAIFPATHFMTNDEHMEVAIAKIQKEMEEQVRLFEAEGKLIEAQRIRQRTEYDVEMLREMGYTSGVENYSRHMDG
RSEGEPPYTLLDFFPEDFLIMIDESHMTMGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYEMEQTDTVIEQIIRPTGLLDPEVEVRPTMGQMDDLLGEINSRADKGERIFITTLTKKMAEDLTDYLKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLIGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSQGHVIMYADT
VTQSMRRAIDETHRRRQIQMAYNEEHGIIPQTIKKDIRDLIAITKANDSEVAEEAVDYNAMTKSERQEAIKKLQKQMQEA
AELLDFELAAQIRDMVLELKAMD

Nucleotide


Download         Length: 1992 bp        

>NTDB_id=43514 SMUGS5_RS03650 WP_002264166.1 751495..753486(+) (uvrB) [Streptococcus mutans GS-5]
ATGATAGATAGGAAAGATAATAACCAGTTTCATCTGGTTTCAAAATATGAGCCGTCTGGTGATCAGCCTGAGGCCATTGA
GGCTTTGGTTGACAATATTGAAGGTGGTGAGAAAGCGCAAATTCTCAAAGGGGCGACTGGGACGGGGAAAACCTATACCA
TGAGCCAAGTTATTCAAAAAGTCAATAAACCAACTTTAGTCATCGCTCATAATAAAACTCTAGCTGGTCAGCTTTACGGT
GAATTTAAGGAATTTTTCCCAGATAATGCAGTTGAGTATTTTGTTTCTTACTATGATTATTATCAGCCTGAAGCCTATGT
GCCATCAAGTGATACCTATATTGAAAAGGATAGTTCAGTTAATGATGAGATTGATAAGCTCCGACATTCGGCAACATCTG
CCCTTTTGGAACGCAATGATGTCATTGTCGTAGCATCCGTCTCCTGTATTTATGGTTTAGGGTCACCCAAGGAATATGCA
GATAGCGTGGTTAGTCTGCGGCCCAGTCAGGAGATTTCTCGCGACCAACTGTTAAATGATTTGGTAGATATTCAGTTTGA
GCGCAACGATATTGATTTCCAGCGGGGACGTTTTCGTGTGCGCGGCGATGTGGTGGAAATTTTTCCAGCATCACGTGATG
AACATGCTTTTCGTGTGGAATTTTTCGGTGATGAGATTGATCGTATCAGAGAAATTGAGAGTTTAACAGGTCGTGTTCTT
GGTGAAGTAGATCACTTGGCTATTTTTCCAGCAACTCACTTTATGACTAACGATGAGCACATGGAAGTGGCTATTGCCAA
GATTCAAAAAGAAATGGAAGAGCAAGTCAGGCTTTTTGAAGCAGAAGGGAAATTGATTGAAGCACAGCGCATTCGCCAAA
GAACAGAGTATGATGTGGAAATGCTGCGGGAGATGGGCTATACTAGCGGCGTTGAAAACTATTCGCGTCATATGGATGGC
CGCAGTGAGGGAGAACCGCCTTATACACTTCTTGACTTTTTTCCAGAGGATTTCCTCATCATGATCGATGAAAGTCACAT
GACTATGGGGCAGATTAAAGGTATGTATAATGGTGACCGATCGCGCAAGGAGATGTTGGTCAACTATGGTTTTCGTCTGC
CAAGTGCGCTGGACAATCGACCGCTGCGTCGAGAAGAATTTGAAAGCCATGTCCATCAGATTGTCTATGTTTCAGCAACA
CCAGGTGACTATGAGATGGAGCAGACGGACACGGTTATTGAGCAAATTATCCGTCCGACTGGTCTCTTGGATCCAGAAGT
GGAAGTTCGGCCAACCATGGGACAAATGGATGATCTGCTGGGTGAAATCAATAGCAGAGCTGATAAAGGCGAGCGGATCT
TTATTACAACCTTAACCAAGAAAATGGCGGAAGATTTGACTGACTACCTCAAGGAAATGGGTGTCAAGGTCAAGTACATG
CACTCGGATATCAAGACTCTGGAACGTACTGAAATTATCCGCGACCTTCGTTTAGGTGTTTTTGATGTTCTTATCGGTAT
CAATTTGCTGCGCGAAGGTATTGATGTGCCAGAGGTTAGTCTGGTTGCCATTCTTGATGCAGACAAAGAAGGTTTTCTCC
GCAATGAACGTGGTCTTATCCAGACCATTGGACGGGCTGCGCGCAACAGTCAAGGACATGTTATTATGTATGCTGATACT
GTGACGCAGTCCATGCGTCGCGCTATTGATGAGACCCACCGCCGCCGCCAAATCCAAATGGCTTACAATGAAGAGCATGG
TATTATTCCACAAACCATCAAAAAAGATATCCGCGATCTTATCGCGATTACAAAAGCAAATGACTCTGAAGTGGCTGAGG
AGGCTGTGGATTATAATGCAATGACCAAATCTGAACGTCAAGAAGCCATCAAGAAACTGCAAAAACAAATGCAAGAAGCA
GCTGAACTGCTTGATTTTGAACTGGCTGCTCAAATCCGCGATATGGTTTTAGAATTGAAGGCGATGGATTAG

Domains

Predicted by InterProScan.

UvrB interaction domain (UvrB_inter)

(164-254)

UvrB/uvrC motif (UVR)

(628-661)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(445-549)

Ultra-violet resistance protein B (UvrB)

(556-598)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

89.291

100

0.893
  uvrB Streptococcus pneumoniae D39

89.291

100

0.893
  uvrB Streptococcus pneumoniae TIGR4

89.14

100

0.891

Multiple sequence alignment