Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   IMP99_RS02060 Genome accession   NZ_CP062855
Coordinates   447747..448379 (-) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli O20:H12 strain Res13-Lact-PEB17-18     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 442747..453379
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IMP99_RS02035 (IMP99_02035) yhfG 442879..443046 (+) 168 WP_000736862.1 YhfG family protein -
  IMP99_RS02040 (IMP99_02040) fic 443036..443638 (+) 603 WP_001280641.1 putative adenosine monophosphate-protein transferase Fic -
  IMP99_RS02045 (IMP99_02045) pabA 443670..444233 (+) 564 WP_000601850.1 aminodeoxychorismate synthase component 2 -
  IMP99_RS02050 (IMP99_02050) argD 444319..445539 (+) 1221 WP_000963792.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  IMP99_RS02055 (IMP99_02055) yhfK 445606..447696 (-) 2091 WP_001309001.1 YccS/YhfK family putative transporter -
  IMP99_RS02060 (IMP99_02060) crp 447747..448379 (-) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  IMP99_RS02065 (IMP99_02065) yhfA 448681..449085 (+) 405 WP_001148908.1 OsmC family protein -
  IMP99_RS02070 (IMP99_02070) prkB 449140..450009 (-) 870 WP_001274680.1 phosphoribulokinase -
  IMP99_RS02075 (IMP99_02075) yheU 450063..450281 (-) 219 WP_000907085.1 YheU family protein -
  IMP99_RS02080 (IMP99_02080) yheT 450275..451297 (-) 1023 WP_000057380.1 hydrolase -
  IMP99_RS02085 (IMP99_02085) yheS 451297..453210 (-) 1914 WP_000634789.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=434852 IMP99_RS02060 WP_000242755.1 447747..448379(-) (crp) [Escherichia coli O20:H12 strain Res13-Lact-PEB17-18]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=434852 IMP99_RS02060 WP_000242755.1 447747..448379(-) (crp) [Escherichia coli O20:H12 strain Res13-Lact-PEB17-18]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAACCTGGCAAAACAACCAGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467