Detailed information NTG0433767

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: HCN55_RS17115
• Genome accession: NZ_CP050532
• Coordinates: 3250383..3252692 (-)
• Length: 769 a.a.
• NCBI ID: WP_003242894.1
• Uniprot ID: Q99027
• Organism: Bacillus subtilis subsp. subtilis str. SMY
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 3245383..3257692

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HCN55_RS17075 (HCN55_17085)	mrpB	3245850..3246281 (+)	432	WP_003228819.1	Na(+)/H(+) antiporter subunit B	-
HCN55_RS17080 (HCN55_17090)	mrpC	3246281..3246622 (+)	342	WP_003220730.1	Na(+)/H(+) antiporter subunit C	-
HCN55_RS17085 (HCN55_17095)	mrpD	3246615..3248096 (+)	1482	WP_003244432.1	Na+/H+ antiporter subunit D	-
HCN55_RS17090 (HCN55_17100)	mrpE	3248102..3248578 (+)	477	WP_003244015.1	Na+/H+ antiporter subunit E	-
HCN55_RS17095 (HCN55_17105)	mrpF	3248578..3248862 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
HCN55_RS17100 (HCN55_17110)	mnhG	3248846..3249220 (+)	375	WP_003244302.1	monovalent cation/H(+) antiporter subunit G	-
HCN55_RS17105 (HCN55_17115)	yuxO	3249259..3249639 (-)	381	WP_003228810.1	hotdog fold thioesterase	-
HCN55_RS17110 (HCN55_17120)	comA	3249658..3250302 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
HCN55_RS17115 (HCN55_17125)	comP	3250383..3252692 (-)	2310	WP_003242894.1	two-component system sensor histidine kinase ComP	Regulator
HCN55_RS17120 (HCN55_17130)	comX	3252707..3252874 (-)	168	WP_003242801.1	competence pheromone ComX	Regulator
HCN55_RS17125 (HCN55_17135)	comQ	3252862..3253761 (-)	900	WP_003243039.1	ComX modifying isoprenyl transferase ComQ	Regulator
HCN55_RS17130 (HCN55_17140)	degQ	3253946..3254086 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
HCN55_RS17135 (HCN55_17145)	-	3254308..3254433 (+)	126	WP_003228793.1	hypothetical protein	-
HCN55_RS17140 (HCN55_17150)	-	3254547..3254915 (+)	369	WP_003243784.1	hypothetical protein	-
HCN55_RS17145 (HCN55_17155)	pdeH	3254891..3256120 (-)	1230	WP_003243525.1	cyclic di-GMP phosphodiesterase	-

Sequence

Protein

• Length: 769 a.a.
• Molecular weight: 89308.77 Da
• Isoelectric Point: 8.2618

>NTDB_id=433767 HCN55_RS17115 WP_003242894.1 3250383..3252692(-) (comP) [Bacillus subtilis subsp. subtilis str. SMY]
MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHL
KWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI
AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLN
LVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQ
FVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKF
NYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKII
EVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLM
FAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYD
LGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDG
VGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL

Nucleotide

• Length: 2310 bp

>NTDB_id=433767 HCN55_RS17115 WP_003242894.1 3250383..3252692(-) (comP) [Bacillus subtilis subsp. subtilis str. SMY]
TTGAAGAACTTAATAAAAAAATTCACAATAGCTGTAATTGTTTTGAGTATCCTTTATATAAGCTATACAACTTATATCAG
TATGAATGGAATTATTATTGGGACTAAGATTCATAAAAATGATAAAAGTCAATTTATGATAGAAGAAATATCGGAATCTT
CATATGGACAATTTGTTGGTCTGAGACAGGGAGACATCATATTAAAAATTAATAAAGAAAAACCTTCAGACAAACATTTG
AAATGGGGATATTTGAGTCATATTAACAGTCTGGATATTTTGAGAAGTGGAAAAAAGATTCATCTCAAAGATTTTGATTT
AGTTACTCTAAATAGACCTTATAGTTTTTTTCTGTTCGTACTTCCTTTGTTTTTTTATTTTTTAAGCATAATATGTATTT
TTTATATACTTAAAGTAAATAAAAAAAGGAGATCATTTGCTGCCTATATTCTTATTCTATTGTTATTAGACATTTCGATA
GCATATATAAGTGCAGGCGGACCATTTAGAGGACATATAATCAATCGGTATATTAACTTGTTTACTTTTATATCTTCTCC
TATTCTTTATCTTCAATTTATACAAAGATACCTTGGAGAAATAGGTAAAACTTTTTTGAATAGAATTTCTTTTCTTTATA
TCATACCAATATTTAATCTTGGTATTGAGTTTTTTCAAGACTATTTACAAGTAGATATTGATTTTTTAGCAACTCTTAAT
TTGGTTTCTTTTGCAACTTTGACTCTATTTTCTTTTTCAGCGATATACTTACATCTTAATAAATATAAATATGCTGAGCA
TTCGTTTATTCTTAAATTACTAATTTTAACAAACACTCTTTCATTTGCGCCTTTTTTGATATTTTTTGTTCTTCCAATAA
TATTTACAGGTAATTATATTTTCCCGGCATTAGCTTCGGCGTCATTACTAGTACTAATTCCGTTCGGGTTAGTATACCAA
TTTGTAGCCAATAAGATGTTTGATATAGAGTTTATCTTAGGAAGAATGAGATACTATGCTCTACTTGCCATGATACCAAC
TCTTCTAATAGTTGGTGCATTAGTTCTGTTTGATGTAATGGACATCCAGATGAACCCTGTGCGTCAAACTGTATTTTTTT
TCGTTGTCATGTTCGCTGTCTTTTATTTTAAAGAGGTCATGGATTTTAAATTTCGGTTAAAACGTTTCTCCGAAAAATTC
AACTATCAGGACAGTATTTTTAAATATACTCAGCTAATGAGGGGTGTAACTTCTCTTCAACAAGTTTTTAAAGAACTGAA
AAATACTATACTGGATGTTTTGCTTGTAAGCAAAGCTTATACCTTTGAGGTTACTCCTGATCACAAAGTGATATTTTTAG
ATAAGCATGAAGTTGGACCGGACTGGAATTTTTATCAAGAGGAATTTGAAAACGTAACTTCAGAAATTGGGAAAATTATA
GAAGTCAATCAAGGCTTTCTTATGAAAGTTGGTGAACGAGGCGGTAGTTCTTATGTTCTGCTTTGTTTATCTAATATTAA
CACTCCCCGGCTAACACGTGATGAAATATCGTGGCTGAAAACACTGTCTTTTTATACAAGTGTGTCCATGGAAAATGTCC
TGCATATTGAGGAGCTCATGGAACATTTGAAGGACTTAAAACAAGAGGGAACCAACCCCATCTGGCTGAAAAAGCTAATG
TTTGCAATCGAAGAAAAACAGCGTTCAGGACTCGCCCGCGATCTCCACGATTCGGTTCTTCAGGATTTGATTTCCTTAAA
ACGCCAGTGTGAGCTGTTTTTGGGTGATTTCAAGAAGGATGATAATCCGTGCCGTGAAGAGGTGCAGGACAAGCTTGTAC
AGATGAATGAGCAGATGTCTGATGTGATTTCGATGACGAGGGAGACGTGTCATGAGCTGCGGCCGCAGCTTCTGTATGAT
CTTGGATTGGTGAAGGCGCTGTCGAAGCTGGTGGCGCAGCAGCAGGAGCGGGTTCCGTTTCATATCCGTTTAAATACCGG
GAGATTTACGGCTTCCCTTGATCTGGATTCGCAGCTGAATTTGTACCGGATCATTCAAGAGTTTCTGTCTAATGCGGTCA
AGCACTCTCAGGCGACGGATGTGCTGATTATGCTCATCAGTATTCAAAACAAAATCGTTCTTCATTATGAGGACGATGGC
GTTGGGTTTGATCAAGAAAAAAATACTGAGCATTCCATGAGCATGGGGCTTTCTGGCATTAAGGAGAGAGTCAGGGCTTT
AGATGGGCGCCTTCGGATTGAAACAAGTGAAGGAAAGGGCTTTAAGGCTGATATTGAAATCGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (568-638)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (679-765)

3D structure

• AlphaFold DB: Q99027

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	100	100	1