Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrB   Type   Machinery gene
Locus tag   SCIM_RS04015 Genome accession   NC_018073
Coordinates   838318..840306 (+) Length   662 a.a.
NCBI ID   WP_003077907.1    Uniprot ID   -
Organism   Streptococcus intermedius JTH08     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 833318..845306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCIM_RS04005 (SCIM_0717) - 834785..835525 (-) 741 WP_003072905.1 amino acid ABC transporter ATP-binding protein -
  SCIM_RS04010 (SCIM_0718) - 835525..837702 (-) 2178 WP_003077901.1 ABC transporter substrate-binding protein/permease -
  SCIM_RS04015 (SCIM_0719) uvrB 838318..840306 (+) 1989 WP_003077907.1 excinuclease ABC subunit UvrB Machinery gene
  SCIM_RS04020 (SCIM_0720) - 840412..841188 (+) 777 WP_003077919.1 hypothetical protein -
  SCIM_RS04025 - 841220..841616 (+) 397 Protein_786 GNAT family N-acetyltransferase -
  SCIM_RS04030 (SCIM_0721) - 841652..842203 (+) 552 WP_003077910.1 DUF1697 domain-containing protein -
  SCIM_RS04035 (SCIM_0722) hemW 842306..843436 (+) 1131 WP_003077909.1 radical SAM family heme chaperone HemW -
  SCIM_RS04040 (SCIM_0723) - 843440..844180 (+) 741 WP_003077896.1 acyl-[acyl-carrier-protein] thioesterase -
  SCIM_RS04045 (SCIM_0724) - 844167..844793 (+) 627 WP_003077921.1 NUDIX hydrolase N-terminal domain-containing protein -

Sequence

Protein


Download         Length: 662 a.a.        Molecular weight: 75658.67 Da        Isoelectric Point: 4.5047

>NTDB_id=43310 SCIM_RS04015 WP_003077907.1 838318..840306(+) (uvrB) [Streptococcus intermedius JTH08]
MINRITDNEFKLVSKYEPSGDQPQAIEELVDNIEGGEKAQILMGATGTGKTYTMSQVIARVNKPTLVIAHNKTLAGQLYG
EFKEFFPNNAVEYFVSYYDYYQPEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYS
DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGKFRVRGDVVEIFPASRDEHAFRVEFFGDEIDRIREVEALTGQVL
GEVDHLAIFPATHFMTNDENMEIAIAKIQAELEQQLAIFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDG
RSEGEPPYTLLDFFPDDFLIMIDESHMTMGQIRGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVHQIVYVSAT
PGDYENEQTDTVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKNERTFITTLTKKMAEDLTDYFKEMGVKVKYM
HSDIKTLERTEIIRDLRLGVFDVLVGINLLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADT
MTQSMQRAIDETARRRAIQMAYNEEHGIVPQTIKKEIRDLISVTKAALPDKEETVEIESLNKQERKDMIKKLEGQMQEAA
GLLDFELAAQIRDMILEIKAMD

Nucleotide


Download         Length: 1989 bp        

>NTDB_id=43310 SCIM_RS04015 WP_003077907.1 838318..840306(+) (uvrB) [Streptococcus intermedius JTH08]
ATGATAAATAGAATTACGGACAATGAATTTAAGTTGGTTTCCAAGTATGAGCCGTCAGGAGATCAACCACAGGCGATTGA
GGAATTAGTTGACAATATTGAGGGTGGAGAGAAGGCCCAGATTCTCATGGGGGCGACTGGTACTGGTAAGACCTATACCA
TGAGTCAAGTTATTGCTCGAGTTAATAAACCGACTCTGGTTATCGCCCATAATAAAACGCTGGCTGGTCAGCTTTATGGT
GAGTTCAAGGAGTTCTTTCCAAATAATGCAGTAGAATATTTTGTTTCCTACTATGATTATTACCAGCCGGAAGCCTATGT
ACCCTCTAGTGATACCTATATTGAAAAGGACAGCTCGGTCAATGACGAGATTGACAAGCTCCGTCACTCAGCAACATCAG
CCCTCTTGGAGCGTAACGATGTGATTGTCGTGGCTTCGGTCTCGTGTATCTATGGTCTAGGTTCGCCTAAGGAATACTCT
GATAGCGTGGTTAGCCTACGTCCGGGTCTAGAAATTTCCCGAGATAAGCTACTCAATGATCTGGTAGATATCCAGTTTGA
GCGTAATGACATTGACTTTCAGCGGGGGAAATTCCGGGTTCGAGGCGATGTGGTGGAGATATTCCCAGCTTCTCGGGATG
AGCATGCCTTTCGGGTAGAGTTTTTTGGTGATGAGATTGACCGCATTCGAGAAGTAGAAGCGTTGACGGGACAAGTTTTG
GGTGAAGTGGACCATTTAGCAATTTTCCCTGCTACTCACTTTATGACAAATGACGAAAATATGGAGATTGCTATTGCCAA
AATTCAGGCCGAGCTGGAGCAGCAACTTGCTATCTTTGAGAAGGAAGGCAAGCTTCTGGAAGCTCAGCGCTTGAAGCAGC
GCACAGAGTATGATATCGAAATGCTGCGTGAAATGGGTTATACGAATGGTGTTGAGAACTATTCTCGCCACATGGACGGC
CGGAGCGAAGGAGAGCCACCTTATACCTTGTTGGATTTCTTCCCTGACGATTTTTTGATCATGATTGATGAGAGTCACAT
GACCATGGGACAGATTCGGGGCATGTACAATGGCGACCGCTCTCGTAAGGAGATGCTGGTTAATTATGGATTCCGCCTAC
CATCTGCCTTGGATAATCGTCCGCTTCGCCGGGAGGAGTTTGAGAGTCACGTTCATCAGATTGTCTATGTATCGGCTACA
CCGGGTGACTATGAAAATGAACAGACGGATACTGTTATTGAGCAGATTATCCGGCCGACAGGGCTTCTGGATCCAGAGGT
GGAAGTTCGACCAACTATGGGGCAGATTGATGATCTTTTAGGCGAAATTAATGCTCGTGTTGAAAAGAATGAACGGACCT
TTATCACGACTTTAACCAAAAAAATGGCAGAAGACTTAACTGACTATTTCAAGGAAATGGGTGTCAAGGTCAAGTACATG
CACTCAGACATCAAGACCTTGGAGCGGACTGAGATTATCCGTGATTTGCGCTTGGGTGTCTTTGACGTTCTGGTTGGGAT
TAACCTGCTGCGTGAGGGAATTGACGTGCCCGAGGTTAGTCTGGTGGCAATTCTCGATGCAGACAAGGAAGGTTTTCTCC
GCAATGAACGTGGTCTTATCCAAACCATTGGACGGGCAGCTCGCAACAGTGAAGGGCATGTGATTATGTATGCAGATACC
ATGACCCAGTCCATGCAGCGCGCTATTGATGAAACTGCCCGCCGTCGAGCAATCCAGATGGCTTACAATGAAGAGCACGG
CATTGTACCGCAGACCATCAAGAAAGAAATCCGCGACCTAATTAGCGTGACCAAGGCTGCCCTACCAGACAAGGAAGAAA
CAGTCGAAATCGAAAGCCTCAACAAGCAAGAGCGCAAGGATATGATCAAGAAACTGGAAGGCCAAATGCAAGAAGCTGCC
GGACTTCTGGACTTCGAACTGGCCGCTCAGATTCGTGATATGATATTGGAAATCAAGGCGATGGATTAA

Domains

Predicted by InterProScan.

Ultra-violet resistance protein B (UvrB)

(556-598)

UvrB/uvrC motif (UVR)

(626-660)

UvrB interaction domain (UvrB_inter)

(164-254)

Type III restriction enzyme, res subunit (ResIII)

(17-143)

Helicase conserved C-terminal domain (Helicase_C)

(443-549)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrB Streptococcus pneumoniae R6

93.807

100

0.938
  uvrB Streptococcus pneumoniae D39

93.807

100

0.938
  uvrB Streptococcus pneumoniae TIGR4

93.656

100

0.937

Multiple sequence alignment