Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   HB753_RS00420 Genome accession   NZ_CP050270
Coordinates   87000..87692 (+) Length   230 a.a.
NCBI ID   WP_002262121.1    Uniprot ID   -
Organism   Streptococcus mutans strain S4     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 82000..92692
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HB753_RS00400 (HB753_00400) - 82111..84723 (-) 2613 WP_019804907.1 ABC transporter permease -
  HB753_RS00405 (HB753_00405) - 84725..85432 (-) 708 WP_002262124.1 ABC transporter ATP-binding protein -
  HB753_RS00410 (HB753_00410) - 85540..86115 (+) 576 WP_002262123.1 TetR/AcrR family transcriptional regulator -
  HB753_RS00415 (HB753_00415) - 86108..86644 (+) 537 WP_002262122.1 DUF177 domain-containing protein -
  HB753_RS00420 (HB753_00420) covR 87000..87692 (+) 693 WP_002262121.1 response regulator GcrR Regulator
  HB753_RS00425 (HB753_00425) nrdR 88062..88553 (+) 492 WP_002262120.1 transcriptional regulator NrdR -
  HB753_RS00430 (HB753_00430) - 88540..89709 (+) 1170 WP_002273097.1 DnaD domain protein -
  HB753_RS00435 (HB753_00435) dnaI 89710..90609 (+) 900 WP_002273096.1 primosomal protein DnaI -
  HB753_RS00440 (HB753_00440) der 90622..91932 (+) 1311 WP_019804906.1 ribosome biogenesis GTPase Der -
  HB753_RS00445 (HB753_00445) - 92007..92633 (+) 627 WP_002273094.1 hypothetical protein -

Sequence

Protein


Download         Length: 230 a.a.        Molecular weight: 26739.72 Da        Isoelectric Point: 4.9899

>NTDB_id=431028 HB753_RS00420 WP_002262121.1 87000..87692(+) (covR) [Streptococcus mutans strain S4]
MAKDILIIEDEKKLAKFVSLELQHEGYEVEVTYDGRSGLERALEKDFDLILLDLMLPEMDGYEVIRRLQLEKTTYVIIIT
ARDSIMDIVTGLDRGADGYIVKPFAIEELLARVRAIFRRQDIEKAKHSSKNDTTYRDLKLDVHNRAAIRNGETIPLTKRE
FDLLNALVENINQVMTREELLARVWKYDQEAETNVVDVYIRYLRGKIDVPGKESYIQTVRGMGYIIRENN

Nucleotide


Download         Length: 693 bp        

>NTDB_id=431028 HB753_RS00420 WP_002262121.1 87000..87692(+) (covR) [Streptococcus mutans strain S4]
ATGGCTAAGGACATTTTAATTATTGAAGATGAAAAAAAACTTGCAAAGTTTGTTTCTTTAGAATTACAACATGAAGGATA
TGAGGTTGAAGTGACATATGATGGGCGTTCTGGCCTGGAAAGAGCACTTGAAAAAGATTTCGATCTCATCCTTCTTGATT
TAATGTTACCAGAGATGGACGGGTATGAAGTGATTCGTCGTTTACAATTGGAAAAGACAACTTATGTTATTATTATCACT
GCTCGTGACTCCATTATGGATATTGTGACTGGTCTTGATCGTGGAGCAGATGGTTATATCGTTAAACCATTTGCTATTGA
AGAATTACTAGCTCGTGTTCGTGCCATATTTCGTCGTCAAGATATTGAGAAAGCTAAACATTCTTCTAAAAATGATACTA
CCTATCGTGATTTGAAATTAGATGTTCATAACCGAGCTGCCATTAGAAATGGTGAGACAATTCCTTTAACTAAACGTGAA
TTTGATTTATTAAATGCTCTTGTAGAAAATATCAATCAAGTCATGACTAGAGAAGAGCTTTTGGCCCGTGTTTGGAAGTA
TGATCAAGAAGCTGAAACTAATGTTGTCGATGTTTATATTCGCTATCTTCGTGGGAAGATTGATGTTCCCGGTAAAGAAA
GCTATATTCAGACTGTCCGCGGCATGGGGTATATCATTCGCGAAAATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(151-225)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

78.07

99.13

0.774
  covR Lactococcus lactis subsp. lactis strain DGCC12653

63.436

98.696

0.626
  vicR Streptococcus mutans UA159

42.857

100

0.43
  micA Streptococcus pneumoniae Cp1015

41.631

100

0.422