Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   HBA50_RS07515 Genome accession   NZ_CP050133
Coordinates   1504004..1506277 (+) Length   757 a.a.
NCBI ID   WP_045498971.1    Uniprot ID   -
Organism   Streptococcus cristatus ATCC 51100     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1499004..1511277
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HBA50_RS07485 (HBA50_07485) - 1499261..1499686 (+) 426 WP_045498983.1 MarR family winged helix-turn-helix transcriptional regulator -
  HBA50_RS07490 (HBA50_07490) - 1499807..1501348 (-) 1542 WP_045498980.1 ABC-F family ATP-binding cassette domain-containing protein -
  HBA50_RS07500 (HBA50_07500) - 1501604..1502260 (-) 657 WP_045498977.1 CBS domain-containing protein -
  HBA50_RS07505 (HBA50_07505) - 1502538..1503392 (-) 855 WP_045498974.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  HBA50_RS07510 (HBA50_07510) - 1503532..1503762 (-) 231 WP_005592360.1 DUF1797 family protein -
  HBA50_RS07515 (HBA50_07515) clpE 1504004..1506277 (+) 2274 WP_045498971.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  HBA50_RS07520 (HBA50_07520) - 1506363..1506767 (+) 405 Protein_1471 transposase -
  HBA50_RS07525 (HBA50_07525) scnK 1507095..1508405 (-) 1311 WP_045498968.1 sensor histidine kinase KdpD Regulator
  HBA50_RS07530 (HBA50_07530) scnR 1508406..1509095 (-) 690 WP_045498965.1 response regulator transcription factor Regulator
  HBA50_RS07535 (HBA50_07535) - 1509267..1510175 (+) 909 WP_008809655.1 ABC transporter ATP-binding protein -
  HBA50_RS07540 (HBA50_07540) - 1510175..1510915 (+) 741 WP_045498958.1 ABC transporter permease -

Sequence

Protein


Download         Length: 757 a.a.        Molecular weight: 83872.14 Da        Isoelectric Point: 5.0628

>NTDB_id=430229 HBA50_RS07515 WP_045498971.1 1504004..1506277(+) (clpE) [Streptococcus cristatus ATCC 51100]
MLCQNCKINESTIHLYTNVNGNKQQIDLCQNCYQIMKTDPNNSLFRGLTQANNQGIDPIDDFFNSLGNFQQPQEPNPNIP
PTQSGGGYGGGGYGGNSNHGGGARQQAPQKPKGLLEEFGINVTEIARKGEIDPVIGRDEEITRVIEILNRRTKNNPVLIG
EPGVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLMDEIRSRQDVILFIDEIHEIVGAG
SAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTD
AAIEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYK
ELQKTSVLDNDIPIISEKTIEHIVEQKTNIPVGDLKEKEQSQLVNLASDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNR
PIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYEEAGQLTERVRRNPYSLILL
DEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMN
RFDGIIEFKPLSKDNLLQIVNLMLDDVNQRLATNDIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLE
NPSEKELKAIMTSNGKILIKSAKKAEAEKTKPDESQS

Nucleotide


Download         Length: 2274 bp        

>NTDB_id=430229 HBA50_RS07515 WP_045498971.1 1504004..1506277(+) (clpE) [Streptococcus cristatus ATCC 51100]
ATGCTTTGTCAAAATTGTAAAATCAATGAATCAACCATCCATCTCTATACAAATGTAAACGGAAACAAGCAGCAGATTGA
CCTTTGTCAAAACTGCTATCAAATTATGAAAACTGACCCTAACAATAGCCTTTTTCGAGGGCTGACTCAGGCTAACAATC
AAGGAATTGATCCTATTGACGATTTCTTTAACAGTCTTGGTAATTTTCAACAACCCCAAGAACCAAATCCAAATATCCCG
CCAACTCAATCTGGAGGAGGCTACGGTGGCGGTGGCTATGGTGGCAATTCCAATCATGGAGGCGGAGCACGCCAACAGGC
TCCGCAAAAGCCAAAAGGTCTCCTAGAAGAGTTTGGTATCAATGTGACTGAGATCGCCCGTAAAGGAGAAATTGACCCTG
TCATCGGTCGGGACGAAGAGATTACTCGTGTCATTGAAATCCTCAACCGCCGCACCAAAAACAATCCTGTCCTTATTGGA
GAGCCCGGTGTCGGAAAAACGGCTGTGGTCGAAGGCCTAGCCCAGAAGATTGTGGATGGGGATGTACCTCATAAACTCCA
AGGCAAGGAAGTTATCCGCCTGGACGTTGTCAGCCTAGTACAAGGGACTGGTATCCGAGGTCAATTTGAAGAGCGGATGC
AGAAGCTCATGGACGAGATTCGCTCTCGTCAAGATGTCATTCTCTTCATTGATGAAATCCATGAAATTGTCGGAGCGGGT
TCTGCTGGCGATGGTAATATGGACGCCGGAAATATCCTCAAACCAGCTCTGGCTCGCGGAGAACTCCAAATGGTTGGGGC
TACTACCCTCAATGAATACCGTATCATTGAGAAGGATGCAGCCCTCGAGCGCCGCATGCAGCCAGTCAAGGTCGACGAGC
CAACAGTAGAGGAAACCATTACCATCCTCAAAGGAATTCAGAAAAAATACGAAGACTACCATCACGTCAAGTACACAGAT
GCGGCTATTGAAGCTGCGGCACTTCTCTCCAACCGCTACATCCAAGACCGCTTCCTGCCAGACAAGGCTATTGACCTCTT
GGACGAGGCTGGCTCTAAGATGAATCTGACCCTCAACTTTGTTGATCCCAAGGTTATTGACCAGCGTCTGATTGAGGCCG
AAAACCTCAAGGCTCAGGCGACTCGTGACGAAGACTTTGAAAAAGCGGCTTACTTCCGCGATCAGATTGCCAAATACAAG
GAACTCCAAAAGACGAGCGTGCTGGATAACGATATCCCAATTATCAGTGAGAAAACCATTGAGCATATCGTGGAGCAAAA
GACCAATATCCCAGTTGGCGATCTCAAAGAAAAGGAACAGTCTCAACTGGTCAATCTCGCCAGCGACTTAAAAGCCCACG
TCATCGGCCAAGATGATGCTGTGGATAAGATTGCCAAGGCCATCCGCCGCAACCGGGTCGGACTAGGAAGTCCTAATCGC
CCAATCGGAAGCTTCCTCTTTGTCGGACCAACTGGTGTCGGTAAGACTGAGCTTTCTAAGCAACTGGCCATTGAGCTCTT
TGGCTCTGCTGACAGCATGATTCGCTTTGATATGAGTGAATACATGGAAAAACACAGCGTGGCCAAACTGGTCGGTGCCC
CTCCAGGCTACGTCGGCTATGAGGAAGCTGGCCAGTTGACTGAGCGAGTCCGCCGCAATCCATACTCGCTCATTCTGTTG
GATGAGGTGGAAAAGGCCCATCCTGATGTTATGCACATGTTCCTACAAGTTCTGGATGATGGCCGCTTGACCGATGGTCA
AGGTCGGACTGTCAGCTTCAAAGACACCATTATCATCATGACATCCAATGCCGGAACGGGCAAGGCTGAAGCCAGCGTTG
GCTTTGGAGCGGCGCGTGAAGGCCGCACCAATTCCGTCTTGGGTGAGCTGGGCAACTTCTTCAGTCCTGAGTTTATGAAC
CGCTTCGACGGCATTATCGAATTCAAGCCACTCAGCAAGGACAATCTGCTGCAGATCGTCAACCTCATGCTGGACGATGT
CAACCAGCGCTTGGCAACCAACGACATTCATCTGGATGTTACTGAGAAGGTCAAGGAAAAATTGGTTGACCTAGGCTACG
ATCCAAAAATGGGCGCTCGCCCACTGCGCCGTACCATTCAAGACCATATCGAAGATGCTATTACTGACTTCTATCTGGAA
AATCCAAGCGAAAAAGAGCTCAAAGCTATCATGACCAGCAATGGCAAGATTCTCATCAAGTCAGCCAAAAAGGCTGAAGC
AGAAAAAACCAAGCCCGATGAAAGCCAAAGCTAA

Domains

Predicted by InterproScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(157-276)

AAA lid domain (AAA_lid_9)

(295-392)

AAA domain (Cdc48 subfamily) (AAA_2)

(480-643)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(651-725)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

87.217

99.207

0.865
  clpE Streptococcus pneumoniae D39

87.217

99.207

0.865
  clpE Streptococcus pneumoniae R6

87.217

99.207

0.865
  clpE Streptococcus pneumoniae TIGR4

87.084

99.207

0.864
  clpE Streptococcus mutans UA159

85.447

98.943

0.845
  clpC Lactococcus lactis subsp. cremoris KW2

76.361

99.472

0.76
  clpC Bacillus subtilis subsp. subtilis str. 168

51.335

89.036

0.457
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.692

85.865

0.41
  clpC Streptococcus pneumoniae Rx1

47.917

82.431

0.395
  clpC Streptococcus pneumoniae D39

47.917

82.431

0.395
  clpC Streptococcus pneumoniae TIGR4

47.756

82.431

0.394
  clpC Streptococcus thermophilus LMD-9

47.52

82.563

0.392
  clpC Streptococcus thermophilus LMG 18311

47.2

82.563

0.39
  clpC Streptococcus mutans UA159

46.965

82.695

0.388